Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy

Twist induces epithelial-mesenchymal transition and cell motility in breast cancer via ITGB1-FAK/ILK signaling axis and its associated downstream network

(2016) Jiajia Yang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease

(2016) Vikram Shettigar et al.   Nature Communications

Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs

(2015) Tiago Fernandes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The insulin-like growth factor I system: Physiological and pathophysiological implication in cardiovascular diseases associated with metabolic syndrome

(2015) Jun Ren et al.   BIOCHEMICAL PHARMACOLOGY

MicroRNA-223 Displays a Protective Role Against Cardiomyocyte Hypertrophy by Targeting Cardiac Troponin I-Interacting Kinase

(2015) Yao-Sheng Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis

(2015) Mun-Wai Cheong et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNA-223 Regulates the Differentiation and Function of Intestinal Dendritic Cells and Macrophages by Targeting C/EBPβ

(2015) Haibo Zhou et al.   Cell Reports

MiRNAs with Apoptosis Regulating Potential Are Differentially Expressed in Chronic Exercise-Induced Physiologically Hypertrophied Hearts

(2015) Subbiah Ramasamy et al.   PLoS One

Hypoxia-inducible factor-1α is required for transforming growth factor-β1-induced type I collagen, periostin and α-smooth muscle actin expression in human periodontal ligament cells

(2014) Teppei Watanabe et al.   ARCHIVES OF ORAL BIOLOGY

miR-223: An inflammatory oncomiR enters the cardiovascular field

(2014) Fatiha Taïbi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Loss of duplexmiR-223 (5p and 3p) aggravates myocardial depression and mortality in polymicrobial sepsis

(2014) Xiaohong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy

(2014) Courtney Moc et al.   CARDIOVASCULAR RESEARCH

Physiological cardiac hypertrophy: Critical role of AKT in the prevention of NHE-1 hyperactivity

(2014) Alejandra M. Yeves et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

An Analysis of the Global Expression of MicroRNAs in an Experimental Model of Physiological Left Ventricular Hypertrophy

(2014) Nidiane C. Martinelli et al.   PLoS One

Inducible re-expression of HEXIM1 causes physiological cardiac hypertrophy in the adult mouse

(2013) Monica M. Montano et al.   CARDIOVASCULAR RESEARCH

MicroRNA-223 Antagonizes Angiogenesis by Targeting β1 Integrin and Preventing Growth Factor Signaling in Endothelial Cells

(2013) Lei Shi et al.   CIRCULATION RESEARCH

Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway

(2013) Zhichao Ma et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

AKIP1, a Cardiac Hypertrophy Induced Protein that Stimulates Cardiomyocyte Growth via the Akt Pathway

(2013) Hongjuan Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-223: infection, inflammation and cancer

(2013) M. Haneklaus et al.   JOURNAL OF INTERNAL MEDICINE

Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes

(2013) Cullen M Taniguchi et al.   NATURE MEDICINE

TNNI3K, a Cardiac-Specific Kinase, Promotes Physiological Cardiac Hypertrophy in Transgenic Mice

(2013) Xiaojian Wang et al.   PLoS One

MicroRNAs in control of cardiac hypertrophy

(2012) Paula A. Da Costa Martins et al.   CARDIOVASCULAR RESEARCH

Role of microRNAs in cardiac remodelling: New insights and future perspectives

(2012) Esteban Orenes-Piñero et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Prolyl Hydroxylase PHD3 Identifies Proinflammatory Macrophages and Its Expression Is Regulated by Activin A

(2012) M. M. Escribese et al.   JOURNAL OF IMMUNOLOGY

Relaxin induces matrix-metalloproteinases-9 and -13 via RXFP1: Induction of MMP-9 involves the PI3K, ERK, Akt and PKC-ζ pathways

(2012) Nisar Ahmad et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Molecular basis of physiological heart growth: fundamental concepts and new players

(2012) Marjorie Maillet et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

GSK-3  regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1 

(2011) D. Flugel et al.   BLOOD

Role of microRNAs in the reperfused myocardium towards post-infarct remodelling

(2011) H. Zhu et al.   CARDIOVASCULAR RESEARCH

Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms

(2011) Georgina M Ellison et al.   HEART

Hypoxia-inducible Factor-1α Protein Negatively Regulates Load-induced Bone Formation

(2011) Ryan C. Riddle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling

(2011) Wenfeng Chu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia

(2011) Jessica M. Cassavaugh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R

(2011) Cheng You Jia et al.   PLoS One

C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

(2010) Pontus Boström et al.   CELL

MicroRNA-494 Targeting Both Proapoptotic and Antiapoptotic Proteins Protects Against Ischemia/Reperfusion-Induced Cardiac Injury

(2010) Xiaohong Wang et al.   CIRCULATION

Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies

(2010) Bianca C. Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

Activation of negative regulators of the hypoxia-inducible factor (HIF) pathway in human end-stage heart failure

(2008) Oliver Zolk et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS