MicroRNAs in control of cardiac hypertrophy

Aerobic Exercise Training–Induced Left Ventricular Hypertrophy Involves Regulatory MicroRNAs, Decreased Angiotensin-Converting Enzyme-Angiotensin II, and Synergistic Regulation of Angiotensin-Converting Enzyme 2-Angiotensin (1-7)

(2011) Tiago Fernandes et al.   HYPERTENSION

Comparison of different miR-21 inhibitor chemistries in a cardiac disease model

(2011) Thomas Thum et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training

(2011) Aaron L. Baggish et al.   JOURNAL OF PHYSIOLOGY-LONDON

MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats

(2011) U. P. R. Soci et al.   PHYSIOLOGICAL GENOMICS

Elevated miR-499 Levels Blunt the Cardiac Stress Response

(2011) Joseph T. C. Shieh et al.   PLoS One

Structural implications into dsRNA binding and RNA silencing suppression by NS3 protein of Rice Hoja Blanca Tenuivirus

(2011) X. Yang et al.   RNA

NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression

(2010) Qi Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dynamic Changes in Lung MicroRNA Profiles During the Development of Pulmonary Hypertension due to Chronic Hypoxia and Monocrotaline

(2010) Paola Caruso et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

miR-21: a miRaculous Socratic paradox

(2010) P. A. da Costa Martins et al.   CARDIOVASCULAR RESEARCH

MicroRNAs and atrial fibrillation: new fundamentals

(2010) Z. Wang et al.   CARDIOVASCULAR RESEARCH

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

(2010) Jacek Krol et al.   CELL

An antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p

(2010) Shweta Rane et al.   CELLULAR SIGNALLING

Thioredoxin 1 Negatively Regulates Angiotensin II–Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7

(2010) Yanfei Yang et al.   CIRCULATION RESEARCH

Frequent Downregulation of miR-34 Family in Human Ovarian Cancers

(2010) D. C. Corney et al.   CLINICAL CANCER RESEARCH

Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes

(2010) Arash Haghikia et al.   EUROPEAN HEART JOURNAL

Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer

(2010) Konstantin J. Dedes et al.   EUROPEAN JOURNAL OF CANCER

miR-1/miR-206 regulate Hsp60 expression contributing to glucose-mediated apoptosis in cardiomyocytes

(2010) Zhi-Xin Shan et al.   FEBS LETTERS

Emerging paradigms of regulated microRNA processing

(2010) M. A. Newman et al.   GENES & DEVELOPMENT

Reciprocal Repression Between MicroRNA-133 and Calcineurin Regulates Cardiac Hypertrophy

(2010) De-Li Dong et al.   HYPERTENSION

miR-9 and NFATc3 Regulate Myocardin in Cardiac Hypertrophy

(2010) Kun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy

(2010) Q. Li et al.   JOURNAL OF CELL SCIENCE

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

Uncoupling of Expression of an Intronic MicroRNA and Its Myosin Host Gene by Exon Skipping

(2010) M. L. Bell et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

(2010) Paula A. da Costa Martins et al.   NATURE CELL BIOLOGY

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

(2010) Jian-Xun Wang et al.   NATURE MEDICINE

Phosphorylation of human Argonaute proteins affects small RNA binding

(2010) Sabine Rüdel et al.   NUCLEIC ACIDS RESEARCH

A novel tissue-specific alternatively spliced form of the A-to-I RNA editing enzyme ADAR2

(2010) Lily Agranat et al.   RNA Biology

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

(2009) Sashwati Roy et al.   CARDIOVASCULAR RESEARCH

Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling

(2009) Zain Paroo et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Reciprocal Regulation of Myocardial microRNAs and Messenger RNA in Human Cardiomyopathy and Reversal of the microRNA Signature by Biomechanical Support

(2009) Scot J. Matkovich et al.   CIRCULATION

Reciprocal Regulation of MicroRNA-1 and Insulin-Like Growth Factor-1 Signal Transduction Cascade in Cardiac and Skeletal Muscle in Physiological and Pathological Conditions

(2009) Leonardo Elia et al.   CIRCULATION

Loss of Cardiac microRNA-Mediated Regulation Leads to Dilated Cardiomyopathy and Heart Failure

(2009) Prakash K. Rao et al.   CIRCULATION RESEARCH

MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts

(2009) Scot J. Matkovich et al.   CIRCULATION RESEARCH

A Family of microRNAs Encoded by Myosin Genes Governs Myosin Expression and Muscle Performance

(2009) Eva van Rooij et al.   DEVELOPMENTAL CELL

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages

(2009) Tina Ruggiero et al.   FASEB JOURNAL

Unique MicroRNA Profile in End-stage Heart Failure Indicates Alterations in Specific Cardiovascular Signaling Networks

(2009) Sathyamangla V. Naga Prasad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

(2009) Thomas Boettger et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice

(2009) Thomas E. Callis et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

(2009) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-1 Negatively Regulates Expression of the Hypertrophy-Associated Calmodulin and Mef2a Genes

(2009) S. Ikeda et al.   MOLECULAR AND CELLULAR BIOLOGY

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

(2009) Saibal Chatterjee et al.   NATURE

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy

(2009) Z. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septation

(2009) A. Saxena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain Renin-Angiotensin System: Fetal Epigenetic Programming by Maternal Protein Restriction During Pregnancy

(2009) Ravi Goyal et al.   Reproductive Sciences

The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators

(2008) Frances V. Fuller-Pace et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

MicroRNA-206: The skeletal muscle-specific myomiR

(2008) J MCCARTHY   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Conditional Dicer Gene Deletion in the Postnatal Myocardium Provokes Spontaneous Cardiac Remodeling

(2008) Paula A. da Costa Martins et al.   CIRCULATION

A Cyclin D2–Rb Pathway Regulates Cardiac Myocyte Size and RNA Polymerase III After Biomechanical Stress in Adult Myocardium

(2008) Ekaterini Angelis et al.   CIRCULATION RESEARCH

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

(2008) Rudy F. Duisters et al.   CIRCULATION RESEARCH

Messenger RNA regulation: to translate or to degrade

(2008) Ann-Bin Shyu et al.   EMBO JOURNAL

Argonaute-2 Expression Is Regulated by Epidermal Growth Factor Receptor and Mitogen-Activated Protein Kinase Signaling and Correlates with a Transformed Phenotype in Breast Cancer Cells

(2008) Brian D. Adams et al.   ENDOCRINOLOGY

microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart

(2008) N. Liu et al.   GENES & DEVELOPMENT

Heart failure: Targeting transcriptional and post-transcriptional control mechanisms of hypertrophy for treatment

(2008) Michael V.G. Latronico et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Molecular regulation of cardiac hypertrophy

(2008) Sean P. Barry et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

NFATc2 Is a Necessary Mediator of Calcineurin-dependent Cardiac Hypertrophy and Heart Failure

(2008) Meriem Bourajjaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cooperative Synergy between NFAT and MyoD Regulates Myogenin Expression and Myogenesis

(2008) Anne-Sophie Armand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miRNA expression in the failing human heart: Functional correlates

(2008) Carmen Sucharov et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-21 Targets Sprouty2 and Promotes Cellular Outgrowths

(2008) Danish Sayed et al.   MOLECULAR BIOLOGY OF THE CELL

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

(2008) William M. Merritt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Frequency and fate of microRNA editing in human brain

(2008) Y. Kawahara et al.   NUCLEIC ACIDS RESEARCH

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

(2008) J.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY