Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway

Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging

(2016) Olga V. Leontieva et al.   Aging-US

MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA

(2012) Qingbo Lang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways

(2012) Shunsuke Noguchi et al.   CANCER LETTERS

MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN

(2012) Li-Yi Zhang et al.   CARCINOGENESIS

The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling

(2012) Rong-Hao Wang et al.   EMBO Molecular Medicine

MiRNA-21 Reverses High Glucose and High Insulin Induced Insulin Resistance in 3T3-L1 Adipocytes through Targeting Phosphatase and Tensin Homologue

(2012) H.-y. Ling et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma

(2012) Pengyu Cao et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Swimming Training in Rats Increases Cardiac MicroRNA-126 Expression and Angiogenesis

(2012) NATAN D. DA SILVA et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells

(2012) Mohit Sachdeva et al.   NUCLEIC ACIDS RESEARCH

Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle

(2011) M. H. Vendelbo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phosphoinositide-3 Kinase Signaling in Cardiac Hypertrophy and Heart Failure

(2011) Toshinori Aoyagi et al.   CURRENT PHARMACEUTICAL DESIGN

MicroRNA in Prostate, Bladder, and Kidney Cancer: A Systematic Review

(2011) James W.F. Catto et al.   EUROPEAN UROLOGY

Aerobic Exercise Training–Induced Left Ventricular Hypertrophy Involves Regulatory MicroRNAs, Decreased Angiotensin-Converting Enzyme-Angiotensin II, and Synergistic Regulation of Angiotensin-Converting Enzyme 2-Angiotensin (1-7)

(2011) Tiago Fernandes et al.   HYPERTENSION

Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells

(2011) Ran Qiang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Attenuation of MicroRNA-22 derepressed PTEN to effectively protect rat cardiomyocytes from hypertrophy

(2011) Xu-Dong Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Focal adhesion kinase — The basis of local hypertrophic signaling domains

(2011) K.G. Franchini   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats

(2011) U. P. R. Soci et al.   PHYSIOLOGICAL GENOMICS

mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy

(2010) Xiaoxiao Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

(2010) Pontus Boström et al.   CELL

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

(2010) Denghong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity

(2010) Sharon Etzion et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Two new miR-16 targets: caprin-1 and HMGA1, proteins implicated in cell proliferation

(2009) Tagrid Kaddar et al.   BIOLOGY OF THE CELL

Patterns of microRNA expression characterize stages of human B-cell differentiation

(2009) Jenny Zhang et al.   BLOOD

Mammalian Target of Rapamycin Is a Critical Regulator of Cardiac Hypertrophy in Spontaneously Hypertensive Rats

(2009) Will Soesanto et al.   HYPERTENSION

Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study

(2009) Edilamar M. Oliveira et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

ThemiR-17∼92cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

(2009) Tamar Uziel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

The roles of microRNA in cancer and apoptosis

(2008) Niamh Lynam-Lennon et al.   BIOLOGICAL REVIEWS

Toward MicroRNA–Based Therapeutics for Heart Disease

(2008) Eva van Rooij et al.   CIRCULATION RESEARCH

Shp2 Negatively Regulates Growth in Cardiomyocytes by Controlling Focal Adhesion Kinase/Src and mTOR Pathways

(2008) Talita M. Marin et al.   CIRCULATION RESEARCH

Cardiac Restricted Overexpression of Kinase-dead Mammalian Target of Rapamycin (mTOR) Mutant Impairs the mTOR-mediated Signaling and Cardiac Function

(2008) Wei-Hua Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-Like Growth Factor I Receptor Signaling Is Required for Exercise-Induced Cardiac Hypertrophy

(2008) Jaetaek Kim et al.   MOLECULAR ENDOCRINOLOGY