miR-188-3p targets skeletal endothelium coupling of angiogenesis and osteogenesis during ageing

Senescent immune cells release grancalcin to promote skeletal aging

(2021) Chang-Jun Li et al.   Cell Metabolism

A common signature of cellular senescence; does it exist?

(2021) Ewa Sikora et al.   AGEING RESEARCH REVIEWS

An Update on the Progress of Isolation, Culture, Storage, and Clinical Application of Human Bone Marrow Mesenchymal Stem/Stromal Cells

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Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

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ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells

(2020) Pedro Fuentes et al.   Nature Communications

Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

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Ni‐induced TGF‐β signaling promotes VEGF‐a secretion via integrin β3 upregulation

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Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation

(2019) Sara G. Romeo et al.   NATURE CELL BIOLOGY

Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence

(2019) Sandeep Saxena et al.   Nature Communications

Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice

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Mechanisms and functions of cellular senescence

(2018) Nicolás Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting skeletal endothelium to ameliorate bone loss

(2018) Ren Xu et al.   NATURE MEDICINE

Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis

(2018) Rie Imamaki et al.   ONCOGENE

Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence

(2018) Jing Wang et al.   Cell Death & Disease

Reactive oxygen species, aging and articular cartilage homeostasis

(2018) Jesalyn A. Bolduc et al.   FREE RADICAL BIOLOGY AND MEDICINE

miR-188 promotes senescence of lineage-negative bone marrow cells by targeting MAP3K3 expression

(2017) Yue Zheng et al.   FEBS LETTERS

Cell–matrix signals specify bone endothelial cells during developmental osteogenesis

(2017) Urs H. Langen et al.   NATURE CELL BIOLOGY

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition

(2017) Sezin Aday et al.   Nature Communications

MiR-497∼195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity

(2017) Mi Yang et al.   Nature Communications

Blood flow controls bone vascular function and osteogenesis

(2016) Saravana K. Ramasamy et al.   Nature Communications

Aging, inflammation, stem cells, and bone healing

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Bone development

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Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

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MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

(2015) Chang-Jun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimer's Disease

(2014) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

(2014) Hui Xie et al.   NATURE MEDICINE

Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src

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Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

(2013) Peng Jiang et al.   NATURE

Sema3A regulates bone-mass accrual through sensory innervations

(2013) Toru Fukuda et al.   NATURE

Development of the Endochondral Skeleton

(2013) F. Long et al.   Cold Spring Harbor Perspectives in Biology

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

(2011) David M Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Improved Culture-Based Isolation of Differentiating Endothelial Progenitor Cells from Mouse Bone Marrow Mononuclear Cells

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Integrin Structure, Activation, and Interactions

(2011) I. D. Campbell et al.   Cold Spring Harbor Perspectives in Biology

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels

(2010) Julie A. Semon et al.   CELL AND TISSUE RESEARCH

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY