Quality control of protein complex assembly by the ubiquitin–proteasome system

Molecular basis for arginine C-terminal degron recognition by Cul2FEM1 E3 ligase

(2021) Xinyan Chen et al.   Nature Chemical Biology

Interactions between nascent proteins translated by adjacent ribosomes drive homomer assembly

(2021) Matilde Bertolini et al.   SCIENCE

Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology

(2021) Rohini R Nair et al.   eLife

Structural basis of human transcription–DNA repair coupling

(2021) Goran Kokic et al.   NATURE

Identification of a quality-control factor that monitors failures during proteasome assembly

(2021) Eszter Zavodszky et al.   SCIENCE

Pervasive functional translation of noncanonical human open reading frames

(2020) Jin Chen et al.   SCIENCE

Structural basis for dimerization quality control

(2020) Elijah L. Mena et al.   NATURE

Translation factor mRNA granules direct protein synthetic capacity to regions of polarized growth

(2019) Mariavittoria Pizzinga et al.   JOURNAL OF CELL BIOLOGY

Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in Saccharomyces cerevisiae

(2019) Christine J. Smoyer et al.   GENETICS

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

(2019) Richard T. Timms et al.   SCIENCE

TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

(2019) Remi Sonneville et al.   eLife

Quality Control of Protein Complex Assembly by a Transmembrane Recognition Factor

(2019) Nivedita Natarajan et al.   MOLECULAR CELL

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons

(2018) Itay Koren et al.   CELL

Compound heterozygous variants of the COG6 gene in a Chinese patient with deficiency of subunit 6 of the conserved oligomeric Golgi complex (COG6-CDG)

(2018) Guoqiang Li et al.   European Journal of Medical Genetics

C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases

(2018) Hsiu-Chuan Lin et al.   MOLECULAR CELL

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation

(2018) Rebekka Wild et al.   SCIENCE

Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling

(2018) Ayala Shiber et al.   NATURE

The atomic structure of a eukaryotic oligosaccharyltransferase complex

(2018) Lin Bai et al.   NATURE

Dimerization quality control ensures neuronal development and survival

(2018) Elijah L. Mena et al.   SCIENCE

Recognition of the Diglycine C-End Degron by CRL2KLHDC2 Ubiquitin Ligase

(2018) Domniţa-Valeria Rusnac et al.   MOLECULAR CELL

Ribosome assembly coming into focus

(2018) Sebastian Klinge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitative Analysis of Human Red Blood Cell Proteome

(2017) Agata H. Bryk et al.   JOURNAL OF PROTEOME RESEARCH

Architecture of the human interactome defines protein communities and disease networks

(2017) Edward L. Huttlin et al.   NATURE

CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis

(2017) Remi Sonneville et al.   NATURE CELL BIOLOGY

UBE2O remodels the proteome during terminal erythroid differentiation

(2017) Anthony T. Nguyen et al.   SCIENCE

UBE2O is a quality control factor for orphans of multiprotein complexes

(2017) Kota Yanagitani et al.   SCIENCE

Degrons in cancer

(2017) Bálint Mészáros et al.   Science Signaling

Operon mRNAs are organized into ORF-centric structures that predict translation efficiency

(2017) David H Burkhardt et al.   eLife

Degrons in cancer

(2017) Bálint Mészáros et al.   Science Signaling

From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals

(2017) Martina Moras et al.   Frontiers in Physiology

The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target

(2017) Philipp M. Cromm et al.   ACS Central Science

Kinetic Analysis of Protein Stability Reveals Age-Dependent Degradation

(2016) Erik McShane et al.   CELL

The life cycle of the 26S proteasome: from birth, through regulation and function and onto its death

(2016) Ido Livneh et al.   CELL RESEARCH

Mechanisms of Selective Autophagy

(2016) Gabriele Zaffagnini et al.   JOURNAL OF MOLECULAR BIOLOGY

Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system

(2016) Min-Kyung Sung et al.   MOLECULAR BIOLOGY OF THE CELL

Proteome complexity and the forces that drive proteome imbalance

(2016) J. Wade Harper et al.   NATURE

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE

A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins

(2016) Min-Kyung Sung et al.   eLife

Global, quantitative and dynamic mapping of protein subcellular localization

(2016) Daniel N Itzhak et al.   eLife

The HECT domain ubiquitin ligase HUWE1 targets unassembled soluble proteins for degradation

(2016) Yue Xu et al.   Cell Discovery

Structure of the human 80S ribosome

(2015) Heena Khatter et al.   NATURE

Operon structure and cotranslational subunit association direct protein assembly in bacteria

(2015) Y.-W. Shieh et al.   SCIENCE

CRL2 aids elimination of truncated selenoproteins produced by failed UGA/Sec decoding

(2015) H.-C. Lin et al.   SCIENCE

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

BTB-ZF transcription factors, a growing family of regulators of early and late B-cell development

(2014) Stéphane Chevrier et al.   IMMUNOLOGY AND CELL BIOLOGY

Protein quality control at the inner nuclear membrane

(2014) Anton Khmelinskii et al.   NATURE

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

Quality control of inner nuclear membrane proteins by the Asi complex

(2014) O. Foresti et al.   SCIENCE

Proteostasis impairment in protein-misfolding and -aggregation diseases

(2014) Mark S. Hipp et al.   TRENDS IN CELL BIOLOGY

Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

(2013) Nathan W. Pierce et al.   CELL

Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

(2013) Joseph A. Marsh et al.   CELL

Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6

(2013) Xiaofei Zhang et al.   EMBO JOURNAL

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Cleaning Up: ER-Associated Degradation to the Rescue

(2012) Jeffrey L. Brodsky   CELL

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27

(2010) Ziguo Zhang et al.   EMBO JOURNAL

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Multiple Proteasome-Interacting Proteins Assist the Assembly of the Yeast 19S Regulatory Particle

(2009) Yasushi Saeki et al.   CELL

Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base

(2009) Minoru Funakoshi et al.   CELL

Assembly Pathway of the Mammalian Proteasome Base Subcomplex Is Mediated by Multiple Specific Chaperones

(2009) Takeumi Kaneko et al.   CELL

Chaperone-mediated pathway of proteasome regulatory particle assembly

(2009) Jeroen Roelofs et al.   NATURE

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

(2009) T. Arnesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebrocostomandibular-like syndrome and a mutation in the conserved oligomeric Golgi complex, subunit 1

(2008) R. Zeevaert et al.   HUMAN MOLECULAR GENETICS

Extensive Analysis of the Cytoplasmic Proteome of Human Erythrocytes Using the Peptide Ligand Library Technology and Advanced Mass Spectrometry

(2008) Florence Roux-Dalvai et al.   MOLECULAR & CELLULAR PROTEOMICS