CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis

Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase

(2016) Daniel R. Semlow et al.   CELL

The Eukaryotic Replisome Goes Under the Microscope

(2016) Mike O’Donnell et al.   CURRENT BIOLOGY

MCM: one ring to rule them all

(2016) Tom D Deegan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Chromosome Duplication in Saccharomyces cerevisiae

(2016) S. P. Bell et al.   GENETICS

p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair

(2016) George Fullbright et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression

(2016) André Franz et al.   Nature Communications

Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin

(2016) André Franz et al.   Frontiers in Genetics

Tethering of SCFDia2 to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase

(2015) Timurs Maculins et al.   CURRENT BIOLOGY

The mechanism of DNA replication termination in vertebrates

(2015) James M. Dewar et al.   NATURE

Clipping or Extracting: Two Ways to Membrane Protein Degradation

(2015) Dönem Avci et al.   TRENDS IN CELL BIOLOGY

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos

(2015) Remi Sonneville et al.   Cell Reports

Terminating the replisome

(2014) Stephen P. Bell   SCIENCE

Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication

(2014) Marija Maric et al.   SCIENCE

Polyubiquitylation drives replisome disassembly at the termination of DNA replication

(2014) Sara Priego Moreno et al.   SCIENCE

Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

(2014) Federico Pelisch et al.   Nature Communications

Dpb2 Integrates the Leading-Strand DNA Polymerase into the Eukaryotic Replisome

(2013) Sugopa Sengupta et al.   CURRENT BIOLOGY

Complex of Fas-associated Factor 1 (FAF1) with Valosin-containing Protein (VCP)-Npl4-Ufd1 and Polyubiquitinated Proteins Promotes Endoplasmic Reticulum-associated Degradation (ERAD)

(2013) Jae-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of p97/VCP (Cdc48) in genome stability

(2013) Bruno Vaz et al.   Frontiers in Genetics

The Dac-tag, an affinity tag based on penicillin-binding protein 5

(2012) David Wei Lee et al.   ANALYTICAL BIOCHEMISTRY

UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation

(2012) Susanne Bandau et al.   BMC BIOLOGY

The dynamics of replication licensing in liveCaenorhabditis elegansembryos

(2012) Remi Sonneville et al.   JOURNAL OF CELL BIOLOGY

Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

(2012) Peter J. Gillespie et al.   METHODS

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

(2012) Hemmo Meyer et al.   NATURE CELL BIOLOGY

Regulation of p97 in the ubiquitin–proteasome system by the UBX protein-family

(2011) Patrik Kloppsteck et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

FAS-Associated Factor 1 (FAF1): Diverse functions and implications for oncogenesis

(2011) Craig W. Menges et al.   CELL CYCLE

MCM2-7 Form Double Hexamers at Licensed Origins inXenopusEgg Extract

(2011) Agnieszka Gambus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

(2011) André Franz et al.   MOLECULAR CELL

The cullin protein family

(2011) Antonio Sarikas et al.   GENOME BIOLOGY

The CRL2LRR-1 ubiquitin ligase regulates cell cycle progression during C. elegans development

(2010) J. Merlet et al.   DEVELOPMENT

CRL2LRR-1 Targets a CDK Inhibitor for Cell Cycle Control in C. elegans and Actin-Based Motility Regulation in Human Cells

(2010) Natalia G. Starostina et al.   DEVELOPMENTAL CELL

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

(2010) Ivar Ilves et al.   MOLECULAR CELL

The Amino-Terminal TPR Domain of Dia2 Tethers SCFDia2 to the Replisome Progression Complex

(2009) Hiroko Morohashi et al.   CURRENT BIOLOGY

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome

(2009) Agnieszka Gambus et al.   EMBO JOURNAL

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation

(2008) David M. Duda et al.   CELL

Temporal Profiling of the Chromatin Proteome Reveals System-wide Responses to Replication Inhibition

(2008) Guennadi A. Khoudoli et al.   CURRENT BIOLOGY

A topoisomerase II-dependent mechanism for resetting replicons at the S-M-phase transition

(2008) O. Cuvier et al.   GENES & DEVELOPMENT

Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation

(2008) Anjanabha Saha et al.   MOLECULAR CELL