UBE2O is a quality control factor for orphans of multiprotein complexes

Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination

(2017) Szymon Juszkiewicz et al.   MOLECULAR CELL

Mechanistic basis for a molecular triage reaction

(2017) Sichen Shao et al.   SCIENCE

UBE2O remodels the proteome during terminal erythroid differentiation

(2017) Anthony T. Nguyen et al.   SCIENCE

Kinetic Analysis of Protein Stability Reveals Age-Dependent Degradation

(2016) Erik McShane et al.   CELL

Chromosome-Specific and Global Effects of Aneuploidy in Saccharomyces cerevisiae

(2016) S. E. Dodgson et al.   GENETICS

Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation

(2016) Eisuke Itakura et al.   MOLECULAR CELL

Proteome complexity and the forces that drive proteome imbalance

(2016) J. Wade Harper et al.   NATURE

Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination

(2016) Ori Braten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins

(2016) Min-Kyung Sung et al.   eLife

The HECT domain ubiquitin ligase HUWE1 targets unassembled soluble proteins for degradation

(2016) Yue Xu et al.   Cell Discovery

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells

(2015) Yusuke Miyazaki et al.   eLife

DISOPRED3: precise disordered region predictions with annotated protein-binding activity

(2014) David T. Jones et al.   BIOINFORMATICS

Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy

(2014) Raymond J Deshaies   BMC BIOLOGY

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

Differential Scales of Protein Quality Control

(2014) Suzanne Wolff et al.   CELL

Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6

(2014) Monica C. Rodrigo-Brenni et al.   MOLECULAR CELL

Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O

(2014) Nazar Mashtalir et al.   MOLECULAR CELL

Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6

(2013) Xiaofei Zhang et al.   EMBO JOURNAL

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

(2012) Nevena V. Dimova et al.   NATURE CELL BIOLOGY

A Calmodulin-Dependent Translocation Pathway for Small Secretory Proteins

(2011) Sichen Shao et al.   CELL

Disorder Targets Misorder in Nuclear Quality Control Degradation: A Disordered Ubiquitin Ligase Directly Recognizes Its Misfolded Substrates

(2011) Joel C. Rosenbaum et al.   MOLECULAR CELL

Protein targeting and degradation are coupled for elimination of mislocalized proteins

(2011) Tara Hessa et al.   NATURE

A ribosome-associating factor chaperones tail-anchored membrane proteins

(2010) Malaiyalam Mariappan et al.   NATURE

Analysis of human   globin gene mutations that impair binding to the   hemoglobin stabilizing protein

(2009) X. Yu et al.   BLOOD

Modification by Single Ubiquitin Moieties Rather Than Polyubiquitination Is Sufficient for Proteasomal Processing of the p105 NF-κB Precursor

(2009) Yelena Kravtsova-Ivantsiv et al.   MOLECULAR CELL