A new discovery of polystyrene microplastics toxicity: The injury difference on bladder epithelium of mice is correlated with the size of exposed particles

Hallmarks of environmental insults

(2021) Annette Peters et al.   CELL

Cadmium-induced Oxidative Stress and Immunosuppression Mediated Mitochondrial Apoptosis via JNK-FoxO3a-PUMA pathway in Common Carp (Cyprinus carpio L.) Gills

(2021) Jianqing Chen et al.   AQUATIC TOXICOLOGY

Combined cytotoxicity of polystyrene nanoplastics and phthalate esters on human lung epithelial A549 cells and its mechanism

(2021) Qingying Shi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

(2021) Junyu Hou et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice

(2021) Yung-Li Wang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene

(2021) Yu Wang et al.   ENVIRONMENTAL POLLUTION

ROS-Induced Hepatotoxicity under Cypermethrin: Involvement of the Crosstalk between Nrf2/Keap1 and NF-κB/iκB-α Pathways Regulated by Proteasome

(2021) Hongjing Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Roles of selenoprotein S in reactive oxygen species-dependent neutrophil extracellular trap formation induced by selenium-deficient arteritis

(2021) Qianru Chi et al.   Redox Biology

Adverse effect of polystyrene microplastics (PS-MPs) on tube formation and viability of human umbilical vein endothelial cells

(2021) Hee-Seop Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Hydrogen sulfide exposure induces pyroptosis in the trachea of broilers via the regulatory effect of circRNA-17828/miR-6631-5p/DUSP6 crosstalk on ROS production

(2021) Nuan Song et al.   JOURNAL OF HAZARDOUS MATERIALS

Public views on plastic pollution: Knowledge, perceived impacts, and pro-environmental behaviours

(2021) Joana Soares et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics-induced ROS overproduction disrupts the skeletal muscle regeneration by converting myoblasts into adipocytes

(2021) Wang Shengchen et al.   JOURNAL OF HAZARDOUS MATERIALS

Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis

(2021) Boxuan Liang et al.   Particle and Fibre Toxicology

Prolonged exposure to traffic-related particulate matter and gaseous pollutants implicate distinct molecular mechanisms of lung injury in rats

(2021) Yu-Teng Jheng et al.   Particle and Fibre Toxicology

Deoxynivalenol induces carp neutrophil apoptosis and necroptosis via CYP450s/ROS/PI3K/AKT pathway

(2021) Chang Ding et al.   AQUACULTURE

H2S exposure induces cell death in the broiler thymus via the ROS-initiated JNK/MST1/FOXO1 pathway

(2021) Qianru Chi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance

(2021) Shi Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The contributions of miR-25-3p, oxidative stress, and heat shock protein in a complex mechanism of autophagy caused by pollutant cadmium in common carp (Cyprinus carpio L.) hepatopancreas

(2021) Zhuo Li et al.   ENVIRONMENTAL POLLUTION

Adsorption and thermal degradation of microplastics from aqueous solutions by Mg/Zn modified magnetic biochars

(2021) Jun Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction

(2020) Kohei Kobatake et al.   CLINICAL CANCER RESEARCH

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Environmental contaminant ammonia triggers epithelial-to-mesenchymal transition-mediated jejunal fibrosis with the disassembly of epithelial cell-cell contacts in chicken

(2020) Hongyuan Jing et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Exposure to polystyrene microplastics induced gene modulated biological responses in zebrafish (Danio rerio)

(2020) Sathisaran Umamaheswari et al.   CHEMOSPHERE

Oxidative stress and mitochondrial dysfunction involved in ammonia-induced nephrocyte necroptosis in chickens

(2020) Qi Han et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats

(2020) Zekang Li et al.   ENVIRONMENTAL POLLUTION

Reproductive toxicity of polystyrene microplastics: In vivo experimental study on testicular toxicity in mice

(2020) Baolian Hou et al.   JOURNAL OF HAZARDOUS MATERIALS

The involvement of miR-6615-5p/Smad7 axis and immune imbalance in ammonia-caused inflammatory injury via NF-κB pathway in broiler kidneys

(2020) Qi Han et al.   POULTRY SCIENCE

Proinflammatory properties and lipid disturbance of polystyrene microplastics in the livers of mice with acute colitis

(2020) Haibin Zheng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Dibutyl phthalate-induced oxidative stress, inflammation and apoptosis in grass carp hepatocytes and the therapeutic use of taxifolin

(2020) Yuan Cui et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis

(2020) Norberto Gonzalez-Juarbe et al.   Cell Reports

The effect of ammonia exposure on energy metabolism and mitochondrial dynamic proteins in chicken thymus: Through oxidative stress, apoptosis, and autophagy

(2020) Syed Waqas Ali Shah et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mixed plasticizers aggravated apoptosis by NOD2-RIP2-NF-κB pathway in grass carp hepatocytes

(2020) Yuan Cui et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics induced male reproductive toxicity in mice

(2020) Haibo Jin et al.   JOURNAL OF HAZARDOUS MATERIALS

H2S exposure-induced oxidative stress promotes LPS-mediated hepatocyte autophagy through the PI3K/AKT/TOR pathway

(2020) Jin-ming Guo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process

(2020) Chi Qianru et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats

(2020) Ru An et al.   TOXICOLOGY

ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes

(2020) Xuan Lai et al.   JOURNAL OF HAZARDOUS MATERIALS

Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells

(2019) Bing Wu et al.   CHEMOSPHERE

Pas de Deux: Control of Anti-tumor Immunity by Cancer-Associated Inflammation

(2019) Shabnam Shalapour et al.   IMMUNITY

Oxidative Stress Indices as Markers of Lead and Cadmium Exposure Toxicity in Auto Technicians in Ibadan, Nigeria

(2019) Ishiaq Olayinka Omotosho   Oxidative Medicine and Cellular Longevity

Temperature-responsive silk-elastinlike protein polymer enhancement of intravesical drug delivery of a therapeutic glycosaminoglycan for treatment of interstitial cystitis/painful bladder syndrome

(2019) M. Martin Jensen et al.   BIOMATERIALS

TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch‐independent, tissue‐specific actions and pathological implications

(2019) Max W. G. Roberts et al.   FASEB JOURNAL

Ammonia regulates chicken tracheal cell necroptosis via the LncRNA-107053293/MiR-148a-3p/FAF1 axis

(2019) Wei Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Ageing, age-related diseases and oxidative stress: What to do next?

(2019) Jiao Luo et al.   AGEING RESEARCH REVIEWS

Ammonia inhalation impaired immune function and mitochondrial integrity in the broilers bursa of fabricius: Implication of oxidative stress and apoptosis

(2019) Syed Waqas Ali Shah et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway

(2019) Xiaoman Xie et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Maternal exposure to different sizes of polystyrene microplastics during gestation causes metabolic disorders in their offspring

(2019) Ting Luo et al.   ENVIRONMENTAL POLLUTION

Avermectin inhibits neutrophil extracellular traps release by activating PTEN demethylation to negatively regulate the PI3K-ERK pathway and reducing respiratory burst in carp

(2019) Shufang Zheng et al.   JOURNAL OF HAZARDOUS MATERIALS

Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

(2019) Boqing Li et al.   CHEMOSPHERE

Freshwater microplastics pollution: Detecting and visualizing emerging trends based on Citespace II

(2019) Liming Yao et al.   CHEMOSPHERE

Klotho Reduces Necroptosis by Targeting Oxidative Stress Involved in Renal Ischemic-Reperfusion Injury

(2018) Yingying Qian et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

High-dose acute exposure of paraquat induces injuries of swim bladder, gastrointestinal tract and liver via neutrophil-mediated ROS in zebrafish and their relevance for human health risk assessment

(2018) Hongcui Liu et al.   CHEMOSPHERE

MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages

(2018) Zhouyang Li et al.   JOURNAL OF IMMUNOLOGY

In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells

(2018) Diya B. Joseph et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

(2018) Yuanxiang Jin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Toxicity-based toxicokinetic/toxicodynamic assessment for bioaccumulation of polystyrene microplastics in mice

(2018) Ying-Fei Yang et al.   JOURNAL OF HAZARDOUS MATERIALS

Plastic and Human Health: A Micro Issue?

(2017) Stephanie L. Wright et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells

(2017) Xiang-Bin Song et al.   Cell Death & Disease

Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead

(2015) Gang Liu et al.   ARCHIVES OF TOXICOLOGY

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

(2015) O. Canli et al.   BLOOD

Occupational exposure to pesticides and bladder cancer risk

(2015) Stella Koutros et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Plastic waste inputs from land into the ocean

(2015) J. R. Jambeck et al.   SCIENCE

Immunohistochemical Expression of Cyclin D1, Cytokeratin 20, and Uroplakin III in Proliferative Urinary Bladder Lesions Induced by o-Nitroanisole in Fischer 344/N Rats

(2015) C. J. Willson et al.   VETERINARY PATHOLOGY

TAK1 control of cell death

(2014) S R Mihaly et al.   CELL DEATH AND DIFFERENTIATION

Involvement of E3 Ubiquitin ligases in Cigarette Smoke associated muscle catabolism

(2014) Oren Rom et al.   FREE RADICAL BIOLOGY AND MEDICINE

Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice

(2012) R. Butler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Profile of Diuron-Induced Toxicity on the Urinary Bladder of Male Wistar Rats to Inform Mode of Action

(2011) Shadia M. Ihlaseh et al.   TOXICOLOGICAL SCIENCES

Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage

(2009) Yu Pan et al.   Small