Deoxynivalenol induces carp neutrophil apoptosis and necroptosis via CYP450s/ROS/PI3K/AKT pathway

New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells

(2021) Xiaojing Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

PI3K mediates tumor necrosis factor induced-necroptosis through initiating RIP1-RIP3-MLKL signaling pathway activation

(2020) Shiping Hu et al.   CYTOKINE

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Genotoxicity and Oxidative Stress in Experimental Hybrid Catfish Exposed to Heavy Metals in a Municipal Landfill Reservoir

(2020) Lamyai Neeratanaphan et al.   International Journal of Environmental Research and Public Health

Micro-algal astaxanthin could improve the antioxidant capability, immunity and ammonia resistance of juvenile Chinese mitten crab, Eriocheir sinensis

(2020) Xiaodong Jiang et al.   FISH & SHELLFISH IMMUNOLOGY

Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis

(2020) Qingqing Liu et al.   FISH & SHELLFISH IMMUNOLOGY

Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.)

(2020) Wei Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Resveratrol relieves chlorothalonil-induced apoptosis and necroptosis through miR-15a/Bcl2-A20 axis in fish kidney cells

(2020) Xiaojing Li et al.   FISH & SHELLFISH IMMUNOLOGY

Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen

(2020) Zhang Yiming et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process

(2020) Chi Qianru et al.   JOURNAL OF HAZARDOUS MATERIALS

Up-Regulation of Trem2 Inhibits Hippocampal Neuronal Apoptosis and Alleviates Oxidative Stress in Epilepsy via the PI3K/Akt Pathway in Mice

(2019) Ai-Hua Liu et al.   Neuroscience Bulletin

Ammonia regulates chicken tracheal cell necroptosis via the LncRNA-107053293/MiR-148a-3p/FAF1 axis

(2019) Wei Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets

(2019) Xi-Chun Wang et al.   Toxins

Deoxynivalenol-Induced Cytotoxicity and Apoptosis in IPEC-J2 Cells Through the Activation of Autophagy by Inhibiting PI3K-AKT-mTOR Signaling Pathway

(2019) Xiaolian Gu et al.   ACS Omega

Yeast cultures alleviate gossypol induced inflammatory response in liver tissue of Ussuri catfish (Pseudobagrus ussuriensis)

(2019) Xianyong Bu et al.   AQUACULTURE

Immune response to abamectin-induced oxidative stress in Chinese mitten crab, Eriocheir sinensis

(2019) Yuhang Hong et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Avermectin inhibits neutrophil extracellular traps release by activating PTEN demethylation to negatively regulate the PI3K-ERK pathway and reducing respiratory burst in carp

(2019) Shufang Zheng et al.   JOURNAL OF HAZARDOUS MATERIALS

Effects of BSF on Podocyte Apoptosis via Regulating the ROS-Mediated PI3K/AKT Pathway in DN

(2019) Fang-qiang Cui et al.   Journal of Diabetes Research

Selenoprotein S silencing triggers mouse hepatoma cells apoptosis and necrosis involving in intracellular calcium imbalance and ROS-mPTP-ATP

(2018) Xiaojing Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Oxidative stress-induced skeletal muscle injury involves in NF-κB/p53-activated immunosuppression and apoptosis response in copper (II) or/and arsenite-exposed chicken

(2018) Hongjing Zhao et al.   CHEMOSPHERE

Icariin ameliorates cisplatin-induced cytotoxicity in human embryonic kidney 293 cells by suppressing ROS-mediated PI3K/Akt pathway

(2018) Yan-dan Zhou et al.   BIOMEDICINE & PHARMACOTHERAPY

Hydrogen sulfide exposure induces jejunum injury via CYP450s/ROS pathway in broilers

(2018) Shufang Zheng et al.   CHEMOSPHERE

Atrazine exposure triggers common carp neutrophil apoptosis via the CYP450s/ROS pathway

(2018) Shengchen Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Chronic Exposure to the Fusarium Mycotoxin Deoxynivalenol: Impact on Performance, Immune Organ, and Intestinal Integrity of Slow-Growing Chickens

(2017) Stephanie Chen et al.   Toxins

Current sights for mechanisms of deoxynivalenol-induced hepatotoxicity and prospective views for future scientific research: A mini review

(2016) Zhao Peng et al.   JOURNAL OF APPLIED TOXICOLOGY

Individual and combined effects of deoxynivalenol and zearalenone on mouse kidney

(2015) Zhen Liang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Occurrence of Fusarium mycotoxins and their dietary intake through beer consumption by the European population

(2015) Yelko Rodríguez-Carrasco et al.   FOOD CHEMISTRY

Acute and subchronic effects on immune responses of carp (Cyprinus carpio L.) after exposure to deoxynivalenol (DON) in feed

(2015) Constanze Pietsch et al.   Mycotoxin Research

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

(2014) You-Tong Wu et al.   Autophagy

Deoxynivalenol induces apoptosis in mouse thymic epithelial cells through mitochondria-mediated pathway

(2014) Daotong Li et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Toxic effects of T-2 toxin and deoxynivalenol on the mitochondrial electron transport system of cardiomyocytes in rats

(2013) Suchitra Ngampongsa et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Deoxynivalenol impairs the immune functions of neutrophils

(2013) Thierry Gauthier et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Clostridium perfringens Beta-Toxin Induces Necrostatin-Inhibitable, Calpain-Dependent Necrosis in Primary Porcine Endothelial Cells

(2013) Delphine Autheman et al.   PLoS One

p53, Oxidative Stress, and Aging

(2010) Dongping Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets

(2010) Osamu Mikami et al.   Journal of Veterinary Science

Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae

(2010) James J. Pestka   Toxins

Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems

(2008) Miroslav Dostalek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY