Cadmium-induced Oxidative Stress and Immunosuppression Mediated Mitochondrial Apoptosis via JNK-FoxO3a-PUMA pathway in Common Carp (Cyprinus carpio L.) Gills

Cadmium induces apoptosis of pig lymph nodes by regulating the PI3K/AKT/HIF-1α pathway

(2021) Lu Yiming et al.   TOXICOLOGY

Binding loop of sunflower trypsin inhibitor 1 serves as a design motif for proteolysis-resistant antimicrobial peptides

(2021) Chensi Wang et al.   Acta Biomaterialia

Forkhead Box O3a requires BAF57, a subunit of chromatin remodeler SWI/SNF complex for induction of p53 up‐regulated modulator of apoptosis (Puma) in a model of Parkinson’s disease

(2020) Priyankar Sanphui et al.   JOURNAL OF NEUROCHEMISTRY

Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils

(2020) Sun Jiaxin et al.   FISH & SHELLFISH IMMUNOLOGY

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Whole transcriptome-based miRNA-mRNA network analysis revealed the mechanism of inflammation-immunosuppressive damage caused by cadmium in common carp spleens

(2020) Jianqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Ammonia-triggered apoptosis via immune function and metabolic process in the thymuses of chickens by proteomics analysis

(2020) Dechun Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis

(2020) Qingqing Liu et al.   FISH & SHELLFISH IMMUNOLOGY

NF-κB pathway took part in the development of apoptosis mediated by miR-15a and oxidative stress via mitochondrial pathway in ammonia-treated chicken splenic lymphocytes

(2020) Dechun Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis

(2020) Y.X. Yang et al.   TOXICOLOGY IN VITRO

Oxidative stress and mitochondrial dysfunction involved in ammonia-induced nephrocyte necroptosis in chickens

(2020) Qi Han et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cooperative application of transcriptomics and ceRNA hypothesis: LncRNA-107052630/miR-205a/G0S2 crosstalk is involved in ammonia-induced intestinal apoptotic injury in chicken

(2020) Shengchen Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

The involvement of miR-6615-5p/Smad7 axis and immune imbalance in ammonia-caused inflammatory injury via NF-κB pathway in broiler kidneys

(2020) Qi Han et al.   POULTRY SCIENCE

The effect of ammonia exposure on energy metabolism and mitochondrial dynamic proteins in chicken thymus: Through oxidative stress, apoptosis, and autophagy

(2020) Syed Waqas Ali Shah et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

H2S exposure-induced oxidative stress promotes LPS-mediated hepatocyte autophagy through the PI3K/AKT/TOR pathway

(2020) Jin-ming Guo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen

(2020) Zhang Yiming et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effects of cadmium exposure on antioxidant enzymes and histological changes in the mud shrimp Austinogebia edulis (Crustacea: Decapoda)

(2019) Shagnika Das et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The co-expression of circRNA and mRNA in the thymuses of chickens exposed to ammonia

(2019) Dechun Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp

(2019) Qiaojian Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury

(2019) Kui-Chao Qu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

iTRAQ-based proteomic analysis on the mitochondrial responses in gill tissues of juvenile olive flounder Paralichthys olivaceus exposed to cadmium

(2019) Zhen Lu et al.   ENVIRONMENTAL POLLUTION

Bioconcentration and depuration of cadmium in the selected tissues of rare minnow (Gobiocypris rarus) and the effect of dietary mulberry leaf supplementation on depuration

(2019) Xiaoqin Xiong et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

In vitro impact of bisphenol A on maturation and function of monocyte-derived dendritic cells in patients with primary Sjögren’s syndrome

(2019) Jing Wang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

miR-187-5p/apaf-1 axis was involved in oxidative stress-mediated apoptosis caused by ammonia via mitochondrial pathway in chicken livers

(2019) Yanmin Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Distribution and ecological risk assessment of cadmium in water and sediment in Longjiang River, China: Implication on water quality management after pollution accident

(2018) Xue-Min Zhao et al.   CHEMOSPHERE

The antagonistic effect of selenium on cadmium-induced apoptosis via PPAR-γ/PI3K/Akt pathway in chicken pancreas

(2018) Xi Jin et al.   JOURNAL OF HAZARDOUS MATERIALS

Atrazine hinders PMA-induced neutrophil extracellular traps in carp via the promotion of apoptosis and inhibition of ROS burst, autophagy and glycolysis

(2018) Shengchen Wang et al.   ENVIRONMENTAL POLLUTION

Impaired immune function and structural integrity in the gills of common carp (Cyprinus carpio L.) caused by chlorpyrifos exposure: Through oxidative stress and apoptosis

(2018) Wanying Jiao et al.   FISH & SHELLFISH IMMUNOLOGY

Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway

(2018) Li-Yuan Wang et al.   BIOCHEMICAL PHARMACOLOGY

The accumulation, histopathology, and intestinal microorganism effects of waterborne cadmium on Carassius auratus gibelio

(2018) Jun Liu et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

The transcription factor Foxp1 preserves integrity of an active Foxp3 locus in extrathymic Treg cells

(2018) Sayantani Ghosh et al.   Nature Communications

Immunosuppression, oxidative stress, and glycometabolism disorder caused by cadmium in common carp (Cyprinus carpio L.): Application of transcriptome analysis in risk assessment of environmental contaminant cadmium

(2018) Jianqing Chen et al.   JOURNAL OF HAZARDOUS MATERIALS

Genome-wide identification of interleukin-17 (IL17) in common carp (Cyprinus carpio) and its expression following Aeromonas hydrophila infection

(2018) Chuanju Dong et al.   GENE

Global burden of late-stage chronic kidney disease resulting from dietary exposure to cadmium, 2015

(2018) Yu Zang et al.   ENVIRONMENTAL RESEARCH

Effects of Selenium and Cadmium on Ion Profiles in the Brains of Chickens

(2016) Runxiang Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Effects of Dietary Selenium Against Lead Toxicity Are Related to the Ion Profile in Chicken Muscle

(2016) Xi Jin et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Downregulation of IL-10 secretion by Treg cells in osteoarthritis is associated with a reduction in Tim-3 expression

(2016) Shufeng Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice via Jak3/Stat3 signaling pathway

(2016) Ting-Ting Di et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Toxicity of oral cadmium intake: Impact on gut immunity

(2015) Marina Ninkov et al.   TOXICOLOGY LETTERS

Hypomethylation of the Treg-Specific Demethylated Region in FOXP3 Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia

(2015) Y. Shimazu et al.   Cancer Immunology Research

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth

(2014) V De Simone et al.   ONCOGENE

The cytokine networks of adaptive immunity in fish

(2013) Tiehui Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression

(2012) Fanny Chalmin et al.   IMMUNITY

JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure

(2012) A H Chaanine et al.   Cell Death & Disease

FOXO3a: a novel player in thyroid carcinogenesis?

(2008) Stefan Karger et al.   ENDOCRINE-RELATED CANCER