Review
Biochemistry & Molecular Biology
Massimiliano Peana, Alessio Pelucelli, Christos T. Chasapis, Spyros P. Perlepes, Vlasoula Bekiari, Serenella Medici, Maria Antonietta Zoroddu
Summary: Cadmium (Cd) is a toxic metal that can cause chronic exposure and increase the risk of various cancers. It is mainly released into the environment through human activities such as industrial processes, pollution, waste incineration, and electronic waste recycling. Cd-induced carcinogenesis mechanisms include oxidative stress, inhibition of antioxidant enzymes, lipid peroxidation, and interference with DNA repair systems. Proper treatments for Cd poisoning and preventive measures to counteract chronic exposure are summarized in this paper.
Article
Psychiatry
Ikeola A. Adeoye
Summary: Alcohol consumption and tobacco exposure among pregnant women in Nigeria are common and neglected issues. Control measures should be implemented during antenatal care.
Review
Medicine, General & Internal
Daniel Glicklich, William H. Frishman
Summary: Exposure to cadmium and lead is widespread and can be related to environmental contamination, occupational sources, food consumption, etc. Lower socioeconomic status increases the risk of heavy metal exposure and related diseases. Current evidence suggests a link between cadmium and lead exposure and various diseases, while Ca EDTA chelation therapy has shown potential in treating patients with certain medical conditions.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
(2021)
Article
Health Care Sciences & Services
Hui-Ling Chen, Jason Chen-Chieh Fang, Chia-Jung Chang, Ti-Feng Wu, I-Kuan Wang, Jen-Fen Fu, Ya-Ching Huang, Ju-Shao Yen, Cheng-Hao Weng, Tzung-Hai Yen
Summary: The study did not find an association between environmental cadmium exposure and dental indices in orthodontic patients.
Review
Immunology
Zhineng Wang, Ying Sun, Wenbo Yao, Qian Ba, Hui Wang
Summary: Cadmium, a biologically non-essential heavy metal, widely present in the environment and foods, is mainly known for its immunotoxicity, which includes modulation of immune cell activity, induction of immune responses, and alteration of antibody production.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Environmental Sciences
Jia-Lang Zheng, Li-Bin Peng, Li-Ping Xia, Jiji Li, Qing-Ling Zhu
Summary: In this study, juvenile female zebrafish were exposed to different concentrations of cadmium (Cd) and their physiological and biochemical endpoints were evaluated. The results showed that growth rate, spawning percentage, estrogen and vitellogenin levels decreased at lower Cd concentrations, but remained stable at higher concentrations. Additionally, the mRNA expression of 27 genes was sensitive to both continuous and intermittent Cd exposure, with vtg3 showing the highest sensitivity as a molecular biomarker.
Article
Environmental Sciences
Xiaoming Zhou, Yijun Feng, Zonglin Gong
Summary: This study found associations between blood levels of heavy metal elements cadmium, lead, mercury, urinary total arsenic, dimethylarsinic acid and elevation of ALT in adults. The associations between blood lead and mercury with ALT elevation were only observed in women.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Engineering, Environmental
Yanhua Wang, You Weng, Lu Lv, Dou Wang, Guiling Yang, Yuanxiang Jin, Qiang Wang
Summary: This study investigated the combined impacts of cadmium and carbofuran on zebrafish and their offspring, and found that this mixture had acute synergistic effects on both adult fish and embryos. Through maternal transmission, the combined exposure caused significant changes in thyroid hormone and VTG levels in the offspring, as well as alterations in the transcriptional levels of genes related to hormones, oxidative stress, and apoptosis.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Adekunle A. Bakare, Adewale O. Fadare, Olusegun I. Ogunsuyi, Omonike C. Bakare
Summary: This study investigated the cytogenotoxicity of Awba Dam water on African catfish, showing that pollutants in the reservoir exceeded standard limits, leading to nuclear abnormalities and systemic disruptions in fish. These findings can be utilized to develop management strategies for the health and biological resources of the reservoir.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
Saif Ullah, Wael Ennab, Quanwei Wei, Changfa Wang, Abdul Quddus, Sheeraz Mustafa, Tavakolikazerooni Hadi, Dagan Mao, Fangxiong Shi
Summary: This study examines the negative effects of lead (Pb) and cadmium (Cd) exposure on the testicular function of bull camels. It reveals the bioaccumulation of these toxic metals, leading to subcellular alterations, reduced testes, and altered hormone synthesis. The findings highlight the significance of understanding and addressing the effects of Pb and Cd exposure on camel reproductive health.
Article
Environmental Sciences
Jun Zhang, Wenxing Yang, Zhuo Li, Feijun Huang, Kui Zhang
Summary: This study investigated the behavioral changes caused by multigenerational exposure to cadmium in C. elegans, and observed its impact on animal behaviors. The results showed that multigenerational cadmium exposure can increase the head thrashing frequency of C. elegans during swimming, and impair its chemotactic behaviors to isoamyl alcohol, diacetyl, and 2-nonanone.
Article
Biochemistry & Molecular Biology
Amine Mosbah, Raouf Dhaouadi, Nouha Ben Abdeljelil, Hamadi Guerbej, Mohamed Banni
Summary: Environmental pollutants, especially metal trace elements, pose an unmitigated threat to the overall life support system. This study evaluated early cadmium toxicity in Mediterranean sea bass and the potential of garlic in preventing cadmium toxicity. The results showed that cadmium induced vascular alterations leading to widespread bleeding and cellular changes, with garlic supplementation having a limited effect on the alterations caused by cadmium.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Environmental Sciences
Lars Barregard, Gerd Sallsten, Thomas Lundh, Johan Molne
Summary: This study found that even low levels of Cd exposure may cause mild tubular atrophy in the kidneys. There is also an association between kidney Hg and renal arteriosclerosis. The results are significant for understanding the effects of these toxic metals on the kidneys.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Katerina Margetaki, Marina Vafeiadi, Mariza Kampouri, Theano Roumeliotaki, Polyxeni Karakosta, Vasiliki Daraki, Manolis Kogevinas, Howard Hu, Maria Kippler, Leda Chatzi
Summary: Maintaining thyroid homeostasis during pregnancy is crucial for fetal development. Studies have shown that exposure to toxic metals, particularly high concentrations of cadmium, antimony, and lead, can significantly affect thyroid hormone levels. Simultaneous exposure to multiple toxic metals may also have a synergistic interaction, exacerbating the effects on thyroid function.
ENVIRONMENTAL POLLUTION
(2021)
Article
Biochemistry & Molecular Biology
Marzenna Nasiadek, Joanna Stragierowicz, Anna Kilanowicz
Summary: Cadmium is an environmental pollutant that poses a health risk. This study investigated the toxic effects of cadmium on the uterus and the protective role of metallothionein. The results showed that cadmium accumulates in the uterus and disrupts the balance of essential elements.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Clinical Neurology
Ishiaq Olayinka Omotosho, Adekunbi Olufunke Akinade, Ikeoluwa Abiola Lagunju, Momoh A. Yakubu
Summary: The study found that children with ASD had lower levels of zinc and magnesium, along with increased lead levels, resulting in inadequate antioxidant capacity and potential abnormality in neuronal transduction leading to the characteristics of ASD such as abnormal cognitive and speech functions.
JOURNAL OF NEURODEVELOPMENTAL DISORDERS
(2021)
Meeting Abstract
Clinical Neurology
N. Ekechukwu, I. Omotosho, T. Hamzat
INTERNATIONAL JOURNAL OF STROKE
(2018)
Article
Pharmacology & Pharmacy
A. A. Onyeaghala, I. O. Omotosho, A. R. Shivashankara
BRITISH JOURNAL OF PHARMACEUTICAL RESEARCH
(2015)