Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis

CD39/CD73/A2a Adenosine Metabolic Pathway: Targets for Moxibustion in Treating DSS-Induced Ulcerative Colitis

(2021) Yuanbing Zhu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation

(2021) Qi Lv et al.   Acta Pharmaceutica Sinica B

Atractylodes oil alleviates diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and intestinal barrier via SCF/c-kit and MLCK/MLC2 pathways

(2021) Ying Xie et al.   JOURNAL OF ETHNOPHARMACOLOGY

Si-Ni-San ameliorates chronic colitis by modulating type I interferons-mediated inflammation

(2021) Yajie Cai et al.   PHYTOMEDICINE

Atractylenolide III Ameliorates TNBS‐Induced Intestinal Inflammation in Mice by Reducing Oxidative Stress and Regulating Intestinal Flora

(2021) Yan Ren et al.   CHEMISTRY & BIODIVERSITY

Effects induced by polyethylene microplastics oral exposure on colon mucin release, inflammation, gut microflora composition and metabolism in mice

(2021) Hanqing Sun et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Dietary fructose improves intestinal cell survival and nutrient absorption

(2021) Samuel R. Taylor et al.   NATURE

Intestinal Microbiota Mediates High-Fructose and High-Fat Diets to Induce Chronic Intestinal Inflammation

(2021) Rong Tan et al.   Frontiers in Cellular and Infection Microbiology

Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway

(2021) Linghang Qu et al.   Frontiers in Pharmacology

Oral Administration of Resveratrol-Selenium-Peptide Nanocomposites Alleviates Alzheimer’s Disease-like Pathogenesis by Inhibiting Aβ Aggregation and Regulating Gut Microbiota

(2021) Changjiang Li et al.   ACS Applied Materials & Interfaces

Sphk1 promotes salivary adenoid cystic carcinoma progression via PI3K/Akt signaling

(2021) Chen-xing Hou et al.   PATHOLOGY RESEARCH AND PRACTICE

Akkermansia muciniphila Alleviates Dextran Sulfate Sodium (DSS)-Induced Acute Colitis by NLRP3 Activation

(2021) Siwen Qu et al.   Microbiology Spectrum

Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2

(2020) Meng-meng Ning et al.   ACTA PHARMACOLOGICA SINICA

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8+ T cells in mice

(2020) Lijuan Wang et al.   GUT

Evodiamine has therapeutic efficacy in ulcerative colitis by increasing Lactobacillus acidophilus levels and acetate production

(2020) Meng-Xia Wang et al.   PHARMACOLOGICAL RESEARCH

Effects of Atractylodes Oil on Inflammatory Response and Serum Metabolites in Adjuvant Arthritis Rats

(2020) Qu Linghang et al.   BIOMEDICINE & PHARMACOTHERAPY

Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease

(2020) Kang Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway

(2020) Jian-yi Dong et al.   ACTA PHARMACOLOGICA SINICA

Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice

(2020) Hui Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites

(2020) Wanghui Jing et al.   PHARMACOLOGICAL RESEARCH

Mogrol, an aglycone of mogrosides, attenuates ulcerative colitis by promoting AMPK activation

(2020) Han liang et al.   PHYTOMEDICINE

Paeoniflorin modulates gut microbial production of indole-3-lactate and epithelial autophagy to alleviate colitis in mice

(2020) Qilin Fan et al.   PHYTOMEDICINE

Chlamydia muridarum Alleviates Colitis via the IL-22/Occludin Signal Pathway

(2020) Xin Wang et al.   Biomed Research International

Berberine in the treatment of ulcerative colitis: A possible pathway through Tuft cells

(2020) Xinyu Xiong et al.   BIOMEDICINE & PHARMACOTHERAPY

Macrophages-targeting mannosylated nanoparticles based on inulin for the treatment of inflammatory bowel disease (IBD)

(2020) Qijuan Sun et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis

(2019) Samuel P. Costello et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Telmisartan and/or chlorogenic acid attenuates fructose-induced non-alcoholic fatty liver disease in rats: Implications of cross-talk between angiotensin, the sphingosine kinase/sphingoine-1-phosphate pathway, and TLR4 receptors

(2019) Iman Alqarni et al.   BIOCHEMICAL PHARMACOLOGY

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Sphk1 promotes ulcerative colitis via activating JAK2/STAT3 signaling pathway

(2019) Jiawen Liu et al.   Human Cell

Deep-Fried Atractylodis Rhizoma Protects against Spleen Deficiency-Induced Diarrhea through Regulating Intestinal Inflammatory Response and Gut Microbiota

(2019) Kun Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target

(2019) Olga A. Sukocheva et al.   PHARMACOLOGY & THERAPEUTICS

Intestinal Absorption of Fructose

(2018) Ronaldo P. Ferraris et al.   Annual Review of Nutrition

Expansion of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor Function in Normal and Cancer Cells: From Membrane Restructuring to Mediation of Estrogen Signaling and Stem Cell Programming

(2018) Olga Sukocheva   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary cells

(2018) Nina Bydlinski et al.   JOURNAL OF BIOTECHNOLOGY

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

Specific Bacteria and Metabolites Associated with Response to Fecal Microbiota Transplantation in Patients with Ulcerative Colitis

(2018) Sudarshan Paramsothy et al.   GASTROENTEROLOGY

Gut microbiome structure and metabolic activity in inflammatory bowel disease

(2018) Eric A. Franzosa et al.   Nature Microbiology

The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS

(2017) Heidi M Staudacher et al.   GUT

Fructose downregulates miR-330 to induce renal inflammatory response and insulin signaling impairment: Attenuation by morin

(2017) Ting-Ting Gu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protective Effect of Protocatechuic Acid on TNBS-Induced Colitis in Mice Is Associated with Modulation of the SphK/S1P Signaling Pathway

(2017) Irene Crespo et al.   Nutrients

Dietary fructose causes defective insulin signalling and ceramide accumulation in the liver that can be reversed by gut microbiota modulation

(2017) Raffaella Crescenzo et al.   Food & Nutrition Research

Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer

(2016) Srividya Venkitachalam et al.   Scientific Reports

Targeting sphingosine kinase 1 (SphK1) and apoptosis by colon-specific delivery formula of resveratrol in treatment of experimental ulcerative colitis in rats

(2013) Amany A. Abdin   EUROPEAN JOURNAL OF PHARMACOLOGY

A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis

(2008) Ashley J. Snider et al.   FASEB JOURNAL