Si-Ni-San ameliorates chronic colitis by modulating type I interferons-mediated inflammation

Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn’s disease

(2020) Ann Elisabet Østvik et al.   Journal of Crohns & Colitis

Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity

(2020) Yang Zong et al.   Frontiers in Pharmacology

Paeoniflorin ameliorates ulcerative colitis by modulating the dendritic cell-mediated TH17/Treg balance

(2020) Kai Zheng et al.   INFLAMMOPHARMACOLOGY

Paeoniflorin modulates gut microbial production of indole-3-lactate and epithelial autophagy to alleviate colitis in mice

(2020) Qilin Fan et al.   PHYTOMEDICINE

Mechanisms of Disease: Inflammatory Bowel Diseases

(2019) Guilherme Piovezani Ramos et al.   MAYO CLINIC PROCEEDINGS

Inflammation and Inflammatory Cytokine Contribute to the Initiation and Development of Ulcerative Colitis and Its Associated Cancer

(2019) Dianbo Yao et al.   INFLAMMATORY BOWEL DISEASES

Involvement of Interferon Regulatory Factor 7 in Nicotine’s Suppression of Antiviral Immune Responses

(2019) Haijun Han et al.   Journal of Neuroimmune Pharmacology

Ulcerative Colitis

(2019) Joseph D. Feuerstein et al.   MAYO CLINIC PROCEEDINGS

Natural products in licorice for the therapy of liver diseases: Progress and future opportunities

(2019) Xiaojiaoyang Li et al.   PHARMACOLOGICAL RESEARCH

Targeting Immune Cell Wiring in Ulcerative Colitis

(2019) Markus F. Neurath et al.   IMMUNITY

The potential and controversy of targeting STAT family members in cancer

(2019) Yannick Verhoeven et al.   SEMINARS IN CANCER BIOLOGY

Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony

(2019) Lingling Zhang et al.   PHARMACOLOGY & THERAPEUTICS

Anti-inflammatory and immune response regulation of Si-Ni-San in 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction

(2018) Hui-Jie Fan et al.   JOURNAL OF ETHNOPHARMACOLOGY

The association of Inflammatory Bowel diseases with autoimmune disorders: a population-based report from the epi-IIRN

(2018) Shahar Bar Yehuda et al.   Journal of Crohns & Colitis

Ulcerative colitis: towards remission

(2018) Michael Eisenstein   NATURE

Protective effects of paeoniflorin on TNBS-induced ulcerative colitis through inhibiting NF-kappaB pathway and apoptosis in mice

(2017) Peiqing Gu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ulcerative colitis

(2017) Ryan Ungaro et al.   LANCET

RIG-I: a multifunctional protein beyond a pattern recognition receptor

(2017) Xiao-xiao Xu et al.   Protein & Cell

Potential Anti-inflammatory Effects of Hesperidin from the Genus Citrus

(2017) Silvia Tejada et al.   CURRENT MEDICINAL CHEMISTRY

Anti TNF-α therapy for ulcerative colitis: current status and prospects for the future

(2016) Daniela Pugliese et al.   Expert Review of Clinical Immunology

The role of type I interferons in intestinal infection, homeostasis, and inflammation

(2014) Hyeseon Cho et al.   IMMUNOLOGICAL REVIEWS

IFNαR Signaling in Effector but Not Regulatory T Cells Is Required for Immune Dysregulation during Type I IFN–Dependent Inflammatory Disease

(2014) Shivani Srivastava et al.   JOURNAL OF IMMUNOLOGY

Ulcerative Colitis

(2014) Joseph D. Feuerstein et al.   MAYO CLINIC PROCEEDINGS

Immunopathology of inflammatory bowel disease

(2014) Kori L Wallace   WORLD JOURNAL OF GASTROENTEROLOGY

Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway

(2013) Jingjing Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Innate and adaptive immunity in inflammatory bowel disease

(2013) Alessandra Geremia et al.   AUTOIMMUNITY REVIEWS

Ulcerative colitis

(2013) A. C. Ford et al.   BMJ-British Medical Journal

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

(2013) Katrin Högner et al.   PLoS Pathogens

Prognostic significance of phosphorylated STAT-1 expression in premenopausal and postmenopausal patients with invasive breast cancer

(2012) Christina Magkou et al.   HISTOPATHOLOGY

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Expression Signature of IFN/STAT1 Signaling Genes Predicts Poor Survival Outcome in Glioblastoma Multiforme in a Subtype-Specific Manner

(2012) Christine W. Duarte et al.   PLoS One

Toll-like receptor-7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis

(2011) Satheesh K. Sainathan et al.   INFLAMMATORY BOWEL DISEASES

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAT2 Contributes to Promotion of Colorectal and Skin Carcinogenesis

(2010) A. M. Gamero et al.   Cancer Prevention Research

Si-Ni-San, a traditional Chinese prescription, and its active ingredient glycyrrhizin ameliorate experimental colitis through regulating cytokine balance

(2009) Yang Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice

(2009) Yang Sun et al.   LIFE SCIENCES

Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer

(2009) N Khodarev et al.   ONCOGENE

Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis

(2007) Satheesh K. Sainathan et al.   INFLAMMATORY BOWEL DISEASES