Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease

Aortic Valve Stenosis

(2020) Philip Roger Goody et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nobiletin exhibits potent inhibition on tumor necrosis factor alpha‐induced calcification of human aortic valve interstitial cells via targeting ABCG2 and AKR1B1

(2019) Kang Xu et al.   PHYTOTHERAPY RESEARCH

Cardiac Rehabilitation for Transcatheter Aortic Valve Replacement

(2019) Franco Tarro Genta   CLINICS IN GERIATRIC MEDICINE

Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction

(2019) Ziwen Li et al.   EUROPEAN HEART JOURNAL

Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve

(2019) Yuming Huang et al.   Stem Cells International

Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

(2018) Florian Schlotter et al.   CIRCULATION

Reassessing endothelial-to-mesenchymal transition in cardiovascular diseases

(2018) Yan Li et al.   Nature Reviews Cardiology

Neural crest-derived cells migrate from nerve to participate in Achilles tendon remodeling

(2018) Kang Xu et al.   WOUND REPAIR AND REGENERATION

Calcific Aortic Valve Disease: a Developmental Biology Perspective

(2018) Punashi Dutta et al.   Current Cardiology Reports

Anthraquinone Emodin Inhibits Tumor Necrosis Factor Alpha-Induced Calcification of Human Aortic Valve Interstitial Cells via the NF-κB Pathway

(2018) Kang Xu et al.   Frontiers in Pharmacology

Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification

(2017) Arkady Rutkovskiy et al.   Journal of the American Heart Association

Cardiac valve cells and their microenvironment—insights from in vitro studies

(2014) Huan Wang et al.   Nature Reviews Cardiology

Heterogeneous Susceptibility of Valve Endothelial Cells to Mesenchymal Transformation in Response to TNFα

(2013) Emily J. Farrar et al.   ANNALS OF BIOMEDICAL ENGINEERING

CD34-negative mesenchymal stem-like cells may act as the cellular origin of human aortic valve calcification

(2013) Anan Nomura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of Cell Subpopulations Expressing Progenitor Cell Markers in Porcine Cardiac Valves

(2013) Huan Wang et al.   PLoS One

Cellular Mechanisms of Aortic Valve Calcification

(2012) Jane A. Leopold   Circulation-Cardiovascular Interventions

Calcific Aortic Valve Disease: Cellular Origins of Valve Calcification

(2011) Nalini M. Rajamannan   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitral Valve Endothelial Cells With Osteogenic Differentiation Potential

(2010) Jill Wylie-Sears et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tumor Necrosis Factor-  Accelerates the Calcification of Human Aortic Valve Interstitial Cells Obtained from Patients with Calcific Aortic Valve Stenosis via the BMP2-Dlx5 Pathway

(2010) Z. Yu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Identification and Characterization of Aortic Valve Mesenchymal Progenitor Cells with Robust Osteogenic Calcification Potential

(2009) Jan-Hung Chen et al.   AMERICAN JOURNAL OF PATHOLOGY