Targeting the residual cardiovascular risk by specific anti-inflammatory interventions as a therapeutic strategy in atherosclerosis
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Title
Targeting the residual cardiovascular risk by specific anti-inflammatory interventions as a therapeutic strategy in atherosclerosis
Authors
Keywords
Inflammation, Cardiovascular disease, NLRP3 Inflammasome, Atherosclerosis, Residual cardiovascular risk, CANTOS
Journal
PHARMACOLOGICAL RESEARCH
Volume 178, Issue -, Pages 106157
Publisher
Elsevier BV
Online
2022-03-05
DOI
10.1016/j.phrs.2022.106157
References
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Note: Only part of the references are listed.- Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
- (2021) Salim S. Virani et al. CIRCULATION
- Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities
- (2021) Xinxin Zhang et al. Journal of Translational Medicine
- Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
- (2021) Paul M Ridker et al. CIRCULATION RESEARCH
- Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials
- (2021) Aernoud T L Fiolet et al. EUROPEAN HEART JOURNAL
- Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
- (2021) Kaspar Broch et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Inhibiting Interleukin-6 to Reduce Cardiovascular Event Rates
- (2021) Paul M Ridker JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial
- (2021) Paul M Ridker et al. LANCET
- Efficacy and safety of colchicine for the prevention of major cardiovascular and cerebrovascular events in patients with coronary artery disease: a systematic review and meta-analysis on 12 869 patients
- (2021) Alessandro Andreis et al. European Journal of Preventive Cardiology
- Interleukin‐1 Blockade Inhibits the Acute Inflammatory Response in Patients With ST‐Segment–Elevation Myocardial Infarction
- (2020) Antonio Abbate et al. Journal of the American Heart Association
- From CANTOS to CIRT to COLCOT to Clinic
- (2020) Paul M Ridker CIRCULATION
- Anti-inflammatory Action of Statins in Cardiovascular Disease: the Role of Inflammasome and Toll-Like Receptor Pathways
- (2020) Khadijeh Koushki et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- NLRP3 Inflammasome and Its Central Role in the Cardiovascular Diseases
- (2020) Yeqing Tong et al. Oxidative Medicine and Cellular Longevity
- Colchicine for Secondary Prevention of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- (2020) Michelle Samuel et al. CANADIAN JOURNAL OF CARDIOLOGY
- Colchicine in Patients with Acute Coronary Syndrome: The Australian COPS Randomized Clinical Trial
- (2020) David C. Tong et al. CIRCULATION
- Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)
- (2020) Nadia Bouabdallaoui et al. EUROPEAN HEART JOURNAL
- MCC950, a selective NLPR3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation
- (2020) Maorong Jiang et al. Journal of Neuroinflammation
- Colchicine in Patients with Chronic Coronary Disease
- (2020) Stefan M. Nidorf et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis
- (2020) Allan L. Klein et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inflammasomes, Neutrophil Extracellular Traps, and Cholesterol
- (2019) Alan R. Tall et al. JOURNAL OF LIPID RESEARCH
- Anticytokine Agents
- (2019) Paul M Ridker CIRCULATION RESEARCH
- Toll-like receptor 2 is overexpressed in Familial Mediterranean fever patients and is inhibited by colchicine treatment
- (2019) Hava Ben-David et al. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
- Immunotherapy for cardiovascular disease
- (2019) Esther Lutgens et al. EUROPEAN HEART JOURNAL
- MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
- (2019) Rebecca C. Coll et al. Nature Chemical Biology
- Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology
- (2019) Daniel F J Ketelhuth et al. CARDIOVASCULAR RESEARCH
- Acute Colchicine Poisoning Causes Endotoxemia via the Destruction of Intestinal Barrier Function: The Curative Effect of Endotoxin Prevention in a Murine Model
- (2019) Kie Horioka et al. DIGESTIVE DISEASES AND SCIENCES
- Miltefosine increases macrophage cholesterol release and inhibits NLRP3-inflammasome assembly and IL-1β release
- (2019) Amanda J. Iacano et al. Scientific Reports
- Novel Insights Into the NLRP3 Inflammasome in Atherosclerosis
- (2019) Ying Jin et al. Journal of the American Heart Association
- Regulatory Mechanisms of the NLRP3 Inflammasome, a Novel Immune-Inflammatory Marker in Cardiovascular Diseases
- (2019) Na An et al. Frontiers in Immunology
- Anti-inflammatory therapy for cardiovascular disease
- (2019) Constantine E. Kosmas et al. Annals of Translational Medicine
- Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction
- (2019) Jean-Claude Tardif et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intensive Statin Therapy Compromises the Adiponectin-AdipoR Pathway in the Human Monocyte-Macrophage Lineage
- (2019) Karina Gasbarrino et al. STROKE
- Inhibition of the NLRP3 inflammasome attenuates foam cell formation of THP-1 macrophages by suppressing ox-LDL uptake and promoting cholesterol efflux
- (2018) Liang Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Association between a functional interleukin 6 receptor genetic variant and risk of depression and psychosis in a population-based birth cohort
- (2018) Golam M. Khandaker et al. BRAIN BEHAVIOR AND IMMUNITY
- Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis and Atherogenesis
- (2018) Marit Westerterp et al. CIRCULATION
- OUP accepted manuscript
- (2018) EUROPEAN HEART JOURNAL
- Interleukin-1 blockade in cardiovascular diseases: a clinical update
- (2018) Leo F Buckley et al. EUROPEAN HEART JOURNAL
- Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial
- (2018) Paul M Ridker et al. LANCET
- Anti-inflammatory therapy with canakinumab for atherosclerotic disease: lessons from the CANTOS trial
- (2018) Peter L. Thompson et al. Journal of Thoracic Disease
- PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
- (2018) Jueqi Chen et al. NATURE
- Low-Dose Methotrexate for the Prevention of Atherosclerotic Events
- (2018) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-1 Beta as a Target for Atherosclerosis Therapy
- (2017) Peter Libby JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial
- (2017) Paul M Ridker et al. LANCET
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction
- (2017) Luís E. Pavillard et al. Oncotarget
- Hemolytic potential of miltefosine is dependent on cell concentration: Implications for in vitro cell cytotoxicity assays and pharmacokinetic data
- (2016) Lais Alonso et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Atorvastatin suppresses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB signaling in PMA-stimulated THP-1 monocytes
- (2016) Fanqi Kong et al. BIOMEDICINE & PHARMACOTHERAPY
- Atorvastatin treatment and LDL cholesterol target attainment in patients at very high cardiovascular risk
- (2016) Ulrich Laufs et al. Clinical Research in Cardiology
- ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces
- (2016) Javier Oroz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Miltefosine Suppresses Hepatic Steatosis by Activating AMPK Signal Pathway
- (2016) Ru Fang et al. PLoS One
- Mechanism and Regulation of NLRP3 Inflammasome Activation
- (2016) Yuan He et al. TRENDS IN BIOCHEMICAL SCIENCES
- Effect of the IL-1 Receptor Antagonist Kineret® on Disease Phenotype in mdx Mice
- (2016) Margaret E. Benny Klimek et al. PLoS One
- Inflammasome-Independent Regulation of IL-1-Family Cytokines
- (2015) Mihai G. Netea et al. Annual Review of Immunology
- Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet
- (2015) A. Abderrazak et al. CIRCULATION
- The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β
- (2015) Jean-Michel Rondeau et al. mAbs
- The receptor NLRP3 is a transcriptional regulator of TH2 differentiation
- (2015) Mélanie Bruchard et al. NATURE IMMUNOLOGY
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- Inflammation and Atherosclerosis
- (2014) Joshua Hartman et al. Cardiology in Review
- The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study
- (2014) A. C. Morton et al. EUROPEAN HEART JOURNAL
- Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study
- (2013) Iain B McInnes et al. ANNALS OF THE RHEUMATIC DISEASES
- Sterol Regulatory Element Binding Protein 2 Activation of NLRP3 Inflammasome in Endothelium Mediates Hemodynamic-Induced Atherosclerosis Susceptibility
- (2013) Han Xiao et al. CIRCULATION
- Nalp3 inflammasome is activated and required for vascular smooth muscle cell calcification
- (2013) Chaoyang Wen et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis
- (2013) Stefan Freigang et al. NATURE IMMUNOLOGY
- Cellular localization of NLRP3 inflammasome
- (2013) Yan Wang et al. Protein & Cell
- Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen
- (2012) Paul M Ridker et al. CIRCULATION
- Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
- (2012) T. P. C. Dorlo et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Low-Dose Colchicine for Secondary Prevention of Cardiovascular Disease
- (2012) Stefan M. Nidorf et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Systematic Review and Meta-Analysis of Methotrexate Use and Risk of Cardiovascular Disease
- (2011) Renata Micha et al. AMERICAN JOURNAL OF CARDIOLOGY
- Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice
- (2011) Vinay Bhaskar et al. ATHEROSCLEROSIS
- Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α
- (2011) Yehuda Kamari et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
- (2011) P Menu et al. Cell Death & Disease
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
- (2010) Kristiina Rajamäki et al. PLoS One
- Optimal dosage and route of administration of methotrexate in rheumatoid arthritis: a systematic review of the literature
- (2008) K Visser et al. ANNALS OF THE RHEUMATIC DISEASES
- Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
- (2008) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
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