Effect of the IL-1 Receptor Antagonist Kineret® on Disease Phenotype in mdx Mice

Changes in calsequestrin, TNF-α, TGF-β and MyoD levels during the progression of skeletal muscle dystrophy inmdxmice: a comparative analysis of the quadriceps, diaphragm and intrinsic laryngeal muscles

(2015) Juliana Barros Maranhão et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

IL-1 receptor-antagonist (IL-1Ra) knockout mice show anxiety-like behavior by aging

(2015) Chisato Wakabayashi et al.   NEUROSCIENCE LETTERS

Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function

(2014) N.V. Ermolova et al.   NEUROMUSCULAR DISORDERS

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

(2013) Christopher R. Heier et al.   EMBO Molecular Medicine

Selective modulation through the glucocorticoid receptor ameliorates muscle pathology inmdxmice

(2013) Tony Huynh et al.   JOURNAL OF PATHOLOGY

Effect of the Arrabidaea chica extract on collagen fiber organization during healing of partially transected tendon

(2013) A.A. Aro et al.   LIFE SCIENCES

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP)

(2013) A Seda Yılmaz-Eliş et al.   Molecular Therapy-Nucleic Acids

N-Acetylcysteine treatment reduces TNF-α levels and myonecrosis in diaphragm muscle of mdx mice

(2012) Rafael de Senzi Moraes Pinto et al.   CLINICAL NUTRITION

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Behavioral, Structural and Molecular Changes following Long-term Hippocampal IL-1β Overexpression in Transgenic Mice

(2011) Amy M. Hein et al.   Journal of Neuroimmune Pharmacology

Inflammasome Up-Regulation and Activation in Dysferlin-Deficient Skeletal Muscle

(2010) Rashmi Rawat et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice

(2010) Y Tang et al.   GENE THERAPY

Eicosapentaenoic acid decreases TNF-α and protects dystrophic muscles of mdx mice from degeneration

(2010) Rafael Ventura Machado et al.   JOURNAL OF NEUROIMMUNOLOGY

Blockade of TNF in vivo using cV1q antibody reduces contractile dysfunction of skeletal muscle in response to eccentric exercise in dystrophic mdx and normal mice

(2010) A.T. Piers et al.   NEUROMUSCULAR DISORDERS

Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

(2009) C. M. Larsen et al.   DIABETES CARE

Imatinib attenuates skeletal muscle dystrophy in mdx mice

(2009) Ping Huang et al.   FASEB JOURNAL

Anakinra for Rheumatoid Arthritis: A Systematic Review

(2009) M. MERTENS et al.   JOURNAL OF RHEUMATOLOGY

Use of pifithrin to inhibit p53-mediated signalling of TNF in dystrophic muscles of mdx mice

(2009) Felicity J. Waters et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Preclinical drug trials in themdxmouse: Assessment of reliable and sensitive outcome measures

(2009) Christopher F. Spurney et al.   MUSCLE & NERVE

Interleukin-1 receptor null mutant mice show decreased anxiety-like behavior and enhanced fear memory

(2009) Ja Wook Koo et al.   NEUROSCIENCE LETTERS

Islet Endothelial Activation and Oxidative Stress Gene Expression Is Reduced by IL-1Ra Treatment in the Type 2 Diabetic GK Rat

(2009) Grégory Lacraz et al.   PLoS One

Update on the management of Duchenne muscular dystrophy

(2008) A Y Manzur et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, Inhibits Apoptosis in Experimental Acute Myocardial Infarction

(2008) Antonio Abbate et al.   CIRCULATION

Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

(2008) Miranda D. Grounds et al.   NEUROBIOLOGY OF DISEASE

Reduced muscle necrosis and long-term benefits in dystrophic mdx mice after cV1q (blockade of TNF) treatment

(2008) Hannah G. Radley et al.   NEUROMUSCULAR DISORDERS

Corticosteroid treatment retards development of ventricular dysfunction in Duchenne muscular dystrophy

(2008) Larry W. Markham et al.   NEUROMUSCULAR DISORDERS