Intranasal Oxytocin Attenuates Cognitive Impairment, β-Amyloid Burden and Tau Deposition in Female Rats with Alzheimer’s Disease: Interplay of ERK1/2/GSK3β/Caspase-3

Acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease – a patent review (2016–present)

(2021) Martina Bortolami et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Oxytocin signalling in dendritic cells regulates immune tolerance in the intestine and alleviates DSS-induced colitis

(2021) Dandan Dou et al.   CLINICAL SCIENCE

Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations

(2021) David C. Yeomans et al.   Translational Psychiatry

Oxytocin reverses Aβ-induced impairment of hippocampal synaptic plasticity in mice

(2020) Junpei Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multifunctional Ligands with Glycogen Synthase Kinase 3 Inhibitory Activity as a New Direction in Drug Research for Alzheimer’s Disease

(2020) Agnieszka Jankowska et al.   CURRENT MEDICINAL CHEMISTRY

Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride‐induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling

(2020) Hala Attia et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer's disease

(2020) Dongsheng Ji et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer’s Disease

(2020) Goonho Park et al.   Cell Reports

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

(2020) Daniel S. Quintana et al.   MOLECULAR PSYCHIATRY

Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro

(2019) Bin Ge et al.   ARCHIVES OF ORAL BIOLOGY

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

Chenodeoxycholic Acid Ameliorates AlCl3-Induced Alzheimer’s Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats

(2019) Firas H. Bazzari et al.   MOLECULES

Meta-Analysis of Randomized Controlled Trials on the Efficacy and Safety of Donepezil, Galantamine, Rivastigmine, and Memantine for the Treatment of Alzheimer’s Disease

(2019) Dan-Dan Li et al.   Frontiers in Neuroscience

Galantamine plasma concentration and cognitive response in Alzheimer’s disease

(2019) Yi-Ting Lin et al.   PeerJ

Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Aβ oligomers

(2019) Chiara Scopa et al.   CELL DEATH AND DIFFERENTIATION

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

(2018) Harald Hampel et al.   BRAIN

Neuroprotective Effects of Oxytocin Hormone after an Experimental Stroke Model and the Possible Role of Calpain-1

(2018) Sepideh Etehadi Moghadam et al.   Journal of Stroke & Cerebrovascular Diseases

Stimulation of ACE2/ANG(1–7)/Mas Axis by Diminazene Ameliorates Alzheimer’s Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway

(2018) Ahmed S. Kamel et al.   MOLECULAR NEUROBIOLOGY

The Oxytocin Receptor: From Intracellular Signaling to Behavior

(2018) Benjamin Jurek et al.   PHYSIOLOGICAL REVIEWS

Neuroprotective Effects of Oxytocin Hormone after an Experimental Stroke Model and the Possible Role of Calpain-1

(2018) Sepideh Etehadi Moghadam et al.   Journal of Stroke & Cerebrovascular Diseases

Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease

(2018) Erin E. Congdon   Frontiers in Neuroscience

Tau Phosphorylation in Female Neurodegeneration: Role of Estrogens, Progesterone, and Prolactin

(2018) Daniel Muñoz-Mayorga et al.   Frontiers in Endocrinology

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Emma Nichols et al.   LANCET NEUROLOGY

The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target (Review)

(2017) Jing Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Intranasal Oxytocin following Uncontrollable Stress Blocks Impairments in Hippocampal Plasticity and Recognition Memory in Stressed Rats

(2017) Seong-Hae Park et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Inhibitory effects of oxytocin and oxytocin receptor antagonist atosiban on the activities of carbonic anhydrase and acetylcholinesterase enzymes in the liver and kidney tissues of rats

(2017) Umit M. Kocyigit et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Amyloid β oligomers (AβOs) in Alzheimer’s disease

(2017) Barbara Mroczko et al.   JOURNAL OF NEURAL TRANSMISSION

Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma

(2017) Jer-Shyung Huang et al.   Oncotarget

Is Oxytocin Relevant for the Affective Disorders?

(2016) A Ciobica   Acta Endocrinologica-Bucharest

Oxytocin Treatment, Circuitry, and Autism: A Critical Review of the Literature Placing Oxytocin Into the Autism Context

(2016) Adam J. Guastella et al.   BIOLOGICAL PSYCHIATRY

Alzheimer's disease: The amyloid hypothesis on trial

(2016) Judith R. Harrison et al.   BRITISH JOURNAL OF PSYCHIATRY

Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice

(2016) Lin Yuan et al.   Journal of Neuroinflammation

Concept of Suicide: Neurophysiological/Genetic Theories and Possible Oxytocin Relevance

(2016) M. Padurariu et al.   NEUROPHYSIOLOGY

Fenugreek Seed Powder Nullified Aluminium Chloride Induced Memory Loss, Biochemical Changes, Aβ Burden and Apoptosis via Regulating Akt/GSK3β Signaling Pathway

(2016) Asokan Prema et al.   PLoS One

Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats

(2015) Madhavan Nampoothiri et al.   BEHAVIOURAL NEUROLOGY

Oxytocin in the regulation of social behaviours in medial amygdala-lesioned mice via the inhibition of the extracellular signal-regulated kinase signalling pathway

(2015) Yu Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Tannoid principles ofEmblica officinalisrenovate cognitive deficits and attenuate amyloid pathologies against aluminum chloride induced rat model of Alzheimer's disease

(2015) Arokiasamy Justin Thenmozhi et al.   NUTRITIONAL NEUROSCIENCE

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

A single dose of oxytocin nasal spray improves higher-order social cognition in schizophrenia

(2015) Adam J. Guastella et al.   SCHIZOPHRENIA RESEARCH

Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease

(2014) Yasuko Kitagishi et al.   Alzheimers Research & Therapy

Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes

(2012) Philip T.T. Ly et al.   JOURNAL OF CLINICAL INVESTIGATION

Amelioration of rotenone-induced dopaminergic cell death in the striatum by oxytocin treatment

(2012) Oytun Erbaş et al.   PEPTIDES

ERK and cell death: ERK1/2 in neuronal death

(2009) Srinivasa Subramaniam et al.   FEBS Journal

Cerebrospinal fluid total tau as a marker of Alzheimer's disease intensity

(2009) Kajsa Sämgård et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

(2008) Dick Terwel et al.   AMERICAN JOURNAL OF PATHOLOGY