Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Aβ oligomers

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Human Adult Neurogenesis: Evidence and Remaining Questions

(2018) Gerd Kempermann et al.   Cell Stem Cell

Alzheimer’s Disease, Oligomers, and Inflammation

(2018) Gianluigi Forloni et al.   JOURNAL OF ALZHEIMERS DISEASE

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

(2017) Carolyn Hollands et al.   Molecular Neurodegeneration

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Alzheimer's disease as oligomeropathy

(2017) Kenjiro Ono   NEUROCHEMISTRY INTERNATIONAL

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease

(2017) Annalisa Nobili et al.   Nature Communications

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis

(2017) S. Lugert et al.   Scientific Reports

Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer’s Disease

(2016) M. S. Unger et al.   MOLECULAR NEUROBIOLOGY

Preserved neurogenesis in non-demented individuals with AD neuropathology

(2016) David Briley et al.   Scientific Reports

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes

(2015) Nataliya Golovyashkina et al.   Molecular Neurodegeneration

HDAC6 and RhoA are novel players in Abeta-driven disruption of neuronal polarity

(2015) Hanako Tsushima et al.   Nature Communications

Adult Neurogenesis in Humans- Common and Unique Traits in Mammals

(2015) Aurélie Ernst et al.   PLOS BIOLOGY

Neurogenesis in the Striatum of the Adult Human Brain

(2014) Aurélie Ernst et al.   CELL

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

(2014) Dennis Janning et al.   MOLECULAR BIOLOGY OF THE CELL

Neutralization of Nerve Growth Factor Impairs Proliferation and Differentiation of Adult Neural Progenitors in the Subventricular Zone

(2014) Raffaella Scardigli et al.   STEM CELLS

Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum

(2014) Giovanni Meli et al.   Nature Communications

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice

(2013) María Díaz-Moreno et al.   NEUROBIOLOGY OF AGING

Analysis of differential plaque depositions in the brains of Tg2576 and Tg-APPswe/PS1dE9 transgenic mouse models of Alzheimer disease

(2012) Tae-Kyung Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology

(2012) Elaine K. Perry et al.   NEUROBIOLOGY OF DISEASE

Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain

(2011) Congmin Wang et al.   CELL RESEARCH

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

Neurogenesis and Alzheimers Disease: Biology and Pathophysiology in Mice and Men

(2010) M. Marlatt et al.   Current Alzheimer Research

Signaling in adult neurogenesis

(2010) Yangling Mu et al.   CURRENT OPINION IN NEUROBIOLOGY

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

(2010) Michael Demars et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE

Soluble oligomeric forms of beta-amyloid (Aβ) peptide stimulate Aβ production via astrogliosis in the rat brain

(2009) J.L. Perez et al.   EXPERIMENTAL NEUROLOGY

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

Direct in Vivo Intracellular Selection of Conformation-sensitive Antibody Domains Targeting Alzheimer's Amyloid-β Oligomers

(2009) Giovanni Meli et al.   JOURNAL OF MOLECULAR BIOLOGY

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Astroglia in dementia and Alzheimer's disease

(2008) J J Rodríguez et al.   CELL DEATH AND DIFFERENTIATION

Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

(2008) Areechun Sotthibundhu et al.   NEUROBIOLOGY OF AGING