Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease

Swallowing Dysfunction and Autonomic Nervous System Dysfunction in Alzheimer's Disease: A Scoping Review of the Evidence

(2013) Rebecca H. Affoo et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Puerarin stimulates proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells via ER-dependent MEK/ERK and PI3K/Akt activation

(2013) Yue Wang et al.   PHYTOMEDICINE

Molecular Mechanisms of Environmental Enrichment: Impairments in Akt/GSK3β, Neurotrophin-3 and CREB Signaling

(2013) Yuan-Shih Hu et al.   PLoS One

Oral Leucine Supplementation Is Sensed by the Brain but neither Reduces Food Intake nor Induces an Anorectic Pattern of Gene Expression in the Hypothalamus

(2013) Thais T. Zampieri et al.   PLoS One

Cost and Cost-Effectiveness of the Mediterranean Diet: Results of a Systematic Review

(2013) Rosella Saulle et al.   Nutrients

Genistein Potentiates the Anti-cancer Effects of Gemcitabine in Human Osteosarcoma via the Downregulation of Akt and Nuclear Factor-κB Pathway

(2012) Chengzhen Liang et al.   Anti-Cancer Agents in Medicinal Chemistry

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Glycogen Synthase Kinase-3 (GSK-3) Inhibitors for the Treatment of Alzheimers Disease

(2012) Miguel Medina et al.   CURRENT PHARMACEUTICAL DESIGN

Does Lithium Prevent Alzheimerʼs Disease?

(2012) Orestes V. Forlenza et al.   DRUGS & AGING

Glycogen synthase kinase-3β regulates anti-inflammatory property of fluoxetine

(2012) Hui-Chen Su et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways

(2012) Dan Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology

(2012) Timothy Revett et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway

(2012) Benxu Cheng et al.   NEUROCHEMISTRY INTERNATIONAL

Review: Membrane-associated misfolded protein propagation in natural transmissible spongiform encephalopathies (TSEs), synthetic prion diseases and Alzheimer's disease

(2012) M. Jeffrey   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer’s disease pathology and is independent of tau, Aβ and TDP-43 pathology

(2011) Ayoub Dakson et al.   ACTA NEUROPATHOLOGICA

Insights into Mitochondrial Dysfunction: Aging, Amyloid-β, and Tau–A Deleterious Trio

(2011) Karen Schmitt et al.   ANTIOXIDANTS & REDOX SIGNALING

α-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes

(2011) Kévin Ragot et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Tau as a Therapeutic Target for Alzheimers Disease

(2011) A. Boutajangout et al.   Current Alzheimer Research

The Possible Involvement of Glycogen Synthase Kinase-3 (GSK-3) in Diabetes, Cancer and Central Nervous System Diseases

(2011) Amar S. et al.   CURRENT PHARMACEUTICAL DESIGN

Prolyl Isomerase Pin1 Promotes Amyloid Precursor Protein (APP) Turnover by Inhibiting Glycogen Synthase Kinase-3β (GSK3β) Activity

(2011) Suk Ling Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway

(2011) Di Wang et al.   JOURNAL OF BIOSCIENCES

Dysregulated phosphorylation of Ca2+/calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s disease

(2011) Lindsay C. Reese et al.   JOURNAL OF NEUROCHEMISTRY

Bending Tau into Shape: The Emerging Role of Peptidyl-Prolyl Isomerases in Tauopathies

(2011) John Koren et al.   MOLECULAR NEUROBIOLOGY

Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling

(2011) J C Garza et al.   MOLECULAR PSYCHIATRY

An Active Fraction of Achyranthes bidentata Polypeptides Prevents Apoptosis Induced by Serum Deprivation in SH-SY5Y Cells Through Activation of PI3K/Akt/Gsk3β Pathways

(2011) Yuntian Shen et al.   NEUROCHEMICAL RESEARCH

Adipocytokines and CD34+ Progenitor Cells in Alzheimer's Disease

(2011) Boris Bigalke et al.   PLoS One

Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo

(2010) Catherine M. Cowan et al.   ACTA NEUROPATHOLOGICA

A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma

(2010) Sandeep Sharma et al.   EXPERIMENTAL NEUROLOGY

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons

(2009) Rui Wang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Leptin reduces Alzheimer’s disease-related tau phosphorylation in neuronal cells

(2008) Steven J. Greco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Simvastatin-Mediated Upregulation of VEGF and BDNF, Activation of the PI3K/Akt Pathway, and Increase of Neurogenesis Are Associated with Therapeutic Improvement after Traumatic Brain Injury

(2008) Hongtao Wu et al.   JOURNAL OF NEUROTRAUMA

The potential for treatment with dietary long-chain polyunsaturated n-3 fatty acids during chemotherapy

(2008) Patricia D. Biondo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Inhibition of Wnt and PI3K Signaling Modulates GSK-3β Activity and Induces Morphological Changes in Cortical Neurons: Role of Tau Phosphorylation

(2008) Octavio Mercado-Gómez et al.   NEUROCHEMICAL RESEARCH

Lithium down-regulates tau in cultured cortical neurons: A possible mechanism of neuroprotection

(2008) A. Rametti et al.   NEUROSCIENCE LETTERS