Transcription activation is enhanced by multivalent interactions independent of phase separation
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Title
Transcription activation is enhanced by multivalent interactions independent of phase separation
Authors
Keywords
gene regulation, phase separation, LLPS, transcription factor, transcription kinetics, residence time, dCas9, optogenetics, BRD4, acetylation, kinetic proofreading, multivalent interactions
Journal
MOLECULAR CELL
Volume 82, Issue 10, Pages 1878-1893.e10
Publisher
Elsevier BV
Online
2022-05-09
DOI
10.1016/j.molcel.2022.04.017
References
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