Transcription activation is enhanced by multivalent interactions independent of phase separation

Functional organization of RNA polymerase II in nuclear subcompartments

(2022) Karsten Rippe et al.   CURRENT OPINION IN CELL BIOLOGY

Sequence-dependent surface condensation of a pioneer transcription factor on DNA

(2022) Jose A. Morin et al.   Nature Physics

Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice

(2021) Nils Schneider et al.   Science Advances

Co-condensation between transcription factor and coactivator p300 modulates transcriptional bursting kinetics

(2021) Liang Ma et al.   MOLECULAR CELL

Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model

(2021) David A Garcia et al.   NUCLEIC ACIDS RESEARCH

The needle and the haystack: single molecule tracking to probe the transcription factor search in eukaryotes

(2021) Matteo Mazzocca et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Single-molecule tracking of transcription protein dynamics in living cells: seeing is believing, but what are we seeing?

(2021) Timothée Lionnet et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Transcription Factor Dynamics

(2021) Feiyue Lu et al.   Cold Spring Harbor Perspectives in Biology

Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene

(2021) Achim P Popp et al.   NUCLEIC ACIDS RESEARCH

Liquid–Liquid Phase Separation in Chromatin

(2021) Karsten Rippe   Cold Spring Harbor Perspectives in Biology

Nuclear condensates of p300 formed though the structured catalytic core can act as a storage pool of p300 with reduced HAT activity

(2021) Yi Zhang et al.   Nature Communications

Compendium of human transcription factor effector domains

(2021) Luis F. Soto et al.   MOLECULAR CELL

Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions

(2020) Jeong-Mo Choi et al.   Annual Review of Biophysics

Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation

(2020) Fabian Erdel et al.   MOLECULAR CELL

Nucleosomal proofreading of activator–promoter interactions

(2020) Robert Shelansky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Regulation in and out of Equilibrium

(2020) Felix Wong et al.   Annual Review of Biophysics

Roles of the BRD4 short isoform in phase separation and active gene transcription

(2020) Xinye Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Long-term association of a transcription factor with its chromatin binding site can stabilize gene expression and cell fate commitment

(2020) J. B. Gurdon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomolecular Condensates and Gene Activation in Development and Disease

(2020) Benjamin R. Sabari   DEVELOPMENTAL CELL

Nucleated transcriptional condensates amplify gene expression

(2020) Ming-Tzo Wei et al.   NATURE CELL BIOLOGY

Transcriptional suppression of ribosomal DNA with phase separation

(2020) Satoru Ide et al.   Science Advances

Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation

(2019) Andrea Callegari et al.   PLoS Genetics

Enhancer Features that Drive Formation of Transcriptional Condensates

(2019) Krishna Shrinivas et al.   MOLECULAR CELL

Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences

(2019) David T. McSwiggen et al.   GENES & DEVELOPMENT

Chemical Control of a CRISPR-Cas9 Acetyltransferase

(2018) Jonathan H. Shrimp et al.   ACS Chemical Biology

Formation of Chromatin Subcompartments by Phase Separation

(2018) Fabian Erdel et al.   BIOPHYSICAL JOURNAL

Imaging dynamic and selective low-complexity domain interactions that control gene transcription

(2018) Shasha Chong et al.   SCIENCE

Coactivator condensation at super-enhancers links phase separation and gene control

(2018) Benjamin R. Sabari et al.   SCIENCE

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

(2018) Won-Ki Cho et al.   SCIENCE

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

(2018) Ann Boija et al.   CELL

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

(2018) Dan Bracha et al.   CELL

Tethering RNA to chromatin for fluorescence microscopy based analysis of nuclear organization

(2017) Teresa Pankert et al.   METHODS

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity

(2017) Alessia Loffreda et al.   Nature Communications

Fast live-cell conventional fluorophore nanoscopy with ImageJ through super-resolution radial fluctuations

(2016) Nils Gustafsson et al.   Nature Communications

Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

(2015) Jesse G. Zalatan et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

(2015) Isaac B Hilton et al.   NATURE BIOTECHNOLOGY

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

(2015) Lauren R Polstein et al.   Nature Chemical Biology

Highly efficient Cas9-mediated transcriptional programming

(2015) Alejandro Chavez et al.   NATURE METHODS

ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging

(2014) Martin Ovesný et al.   BIOINFORMATICS

Specificity, propagation, and memory of pericentric heterochromatin

(2014) K. Muller-Ott et al.   Molecular Systems Biology

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences

(2013) Katharina Günther et al.   NUCLEIC ACIDS RESEARCH

Erratum to “Reactive transport in aquatic ecosystems: Rapid model prototyping in the open source software R” [Environ. Modell. Softw. 32 (2012) 49–60]

(2012) Karline Soetaert et al.   ENVIRONMENTAL MODELLING & SOFTWARE

EBImage--an R package for image processing with applications to cellular phenotypes

(2010) G. Pau et al.   BIOINFORMATICS

Functional Interplay between Acetylation and Methylation of the RelA Subunit of NF- B

(2010) X. D. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Single Cell Analysis of Transcriptional Activation Dynamics

(2010) Ilona U. Rafalska-Metcalf et al.   PLoS One

Dynamics of Telomeres and Promyelocytic Leukemia Nuclear Bodies in a Telomerase-negative Human Cell Line

(2009) Thibaud Jegou et al.   MOLECULAR BIOLOGY OF THE CELL

Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes

(2008) Mike Heilemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION