Novel β-Hairpin Antimicrobial Peptides Containing the β-Turn Sequence of -RRRF- Having High Cell Selectivity and Low Incidence of Drug Resistance
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Title
Novel β-Hairpin Antimicrobial Peptides Containing the β-Turn Sequence of -RRRF- Having High Cell Selectivity and Low Incidence of Drug Resistance
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 65, Issue 7, Pages 5625-5641
Publisher
American Chemical Society (ACS)
Online
2022-03-21
DOI
10.1021/acs.jmedchem.1c02140
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Note: Only part of the references are listed.- Encouraging the Development of New Antibiotics: Are Financial Incentives the Right Way Forward? A Systematic Review and Case Study
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- Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS interaction and targeting of host cell membranes
- (2021) Andra B. Schromm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protective effects of 6‐gingerol on 6‐hydroxydopamine‐induced apoptosis in PC12 cells through modulation of SAPK/JNK and survivin activation
- (2021) Farzaneh‐Sadat Rezazadeh‐Shojaee et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Antimicrobial host defence peptides: functions and clinical potential
- (2020) Neeloffer Mookherjee et al. NATURE REVIEWS DRUG DISCOVERY
- Enhanced cell selectivity of hybrid peptides with potential antimicrobial activity and immunomodulatory effect
- (2020) Xiaokang Miao et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Synthesis and anti-pseudomonal activity of new ß-Ala modified analogues of the antimicrobial peptide anoplin
- (2020) Chao Zhong et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Cross‐Strand Interaction, Central Bending, and Sequence Pattern Act as Biomodulators of Simplified β‐Hairpin Antimicrobial Amphiphiles
- (2020) Changxuan Shao et al. Small
- Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance
- (2020) Chao Zhong et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria
- (2020) Ningyi Zhu et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Antimicrobial Peptides with High Proteolytic Resistance for Combating Gram-Negative Bacteria
- (2019) Jiajun Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Bioactivity and Bactericidal Mechanism of Histidine-Rich β-Hairpin Peptide Against Gram-Negative Bacteria
- (2019) Na Dong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase
- (2019) Bo Ma et al. Nature Communications
- Antimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria
- (2019) Chao Zhong et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Study on the effects of different dimerization positions on biological activity of partial d-Amino acid substitution analogues of Anoplin
- (2019) Chao Zhong et al. MICROBIAL PATHOGENESIS
- Central β-turn increases the cell selectivity of imperfectly amphipathic α-helical peptides
- (2018) Changxuan Shao et al. Acta Biomaterialia
- Short arginine-rich lipopeptides: From self-assembly to antimicrobial activity
- (2018) Emilia Sikorska et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- OUP accepted manuscript
- (2018) CLINICAL INFECTIOUS DISEASES
- Short Symmetric-End Antimicrobial Peptides Centered on β-Turn Amino Acids Unit Improve Selectivity and Stability
- (2018) Na Dong et al. Frontiers in Microbiology
- The drug-resistant bacteria that pose the greatest health threats
- (2017) Cassandra Willyard NATURE
- Adaptation of a bacterial membrane permeabilization assay for quantitative evaluation of benzalkonium chloride as a membrane-disrupting agent
- (2017) Julien Gravel et al. MedChemComm
- Effects of Hydrophobic Amino Acid Substitutions on Antimicrobial Peptide Behavior
- (2017) Kimberly D. Saint Jean et al. Probiotics and Antimicrobial Proteins
- The effects of LPS on the activity of Trp-containing antimicrobial peptides against Gram-negative bacteria and endotoxin neutralization
- (2016) Dejing Shang et al. Acta Biomaterialia
- Hairpin structure stability plays a role in the activity of two antimicrobial peptides
- (2016) Kalkena Sivanesam et al. FEBS LETTERS
- Past, Present, and Future of Antibacterial Economics: Increasing Bacterial Resistance, Limited Antibiotic Pipeline, and Societal Implications
- (2016) Katherine H. Luepke et al. PHARMACOTHERAPY
- Antimicrobial activity and membrane-active mechanism of tryptophan zipper-like β-hairpin antimicrobial peptides
- (2015) Lin Xu et al. AMINO ACIDS
- The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
- (2015) Xian-Zhi Li et al. CLINICAL MICROBIOLOGY REVIEWS
- Enhanced Amphiphilic Profile of a Short β-Stranded Peptide Improves Its Antimicrobial Activity
- (2015) Giorgia Manzo et al. PLoS One
- High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs
- (2015) Jiajun Wang et al. Scientific Reports
- Strategies employed in the design and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials
- (2014) Zhan Yuin Ong et al. ADVANCED DRUG DELIVERY REVIEWS
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- (2014) Alessandra V.R. da Silva et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Cysteine deleted protegrin-1 (CDP-1): Anti-bacterial activity, outer-membrane disruption and selectivity
- (2014) Harini Mohanram et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Antimicrobial potency and selectivity of simplified symmetric-end peptides
- (2014) Na Dong et al. BIOMATERIALS
- Strand Length-Dependent Antimicrobial Activity and Membrane-Active Mechanism of Arginine- and Valine-Rich β-Hairpin-Like Antimicrobial Peptides
- (2012) Na Dong et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Cationic Surfactants Derived from Lysine: Effects of Their Structure and Charge Type on Antimicrobial and Hemolytic Activities
- (2011) A. Colomer et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tryptophan residues: Scarce in proteins but strong stabilizers of β-hairpin peptides
- (2010) Clara M. Santiveri et al. BIOPOLYMERS
- Structure and mechanism of β-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR spectroscopy
- (2009) Ming Tang et al. Molecular BioSystems
- Potential of immunomodulatory host defense peptides as novel anti-infectives
- (2009) Donna M. Easton et al. TRENDS IN BIOTECHNOLOGY
- Using Fluorous Amino Acids To Probe the Effects of Changing Hydrophobicity on the Physical and Biological Properties of the β-Hairpin Antimicrobial Peptide Protegrin-1†
- (2008) Lindsey M. Gottler et al. BIOCHEMISTRY
- The Role of Hydrophobicity in the Antimicrobial and Hemolytic Activities of Polymethacrylate Derivatives
- (2008) Kenichi Kuroda et al. CHEMISTRY-A EUROPEAN JOURNAL
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