Binding loop of sunflower trypsin inhibitor 1 serves as a design motif for proteolysis-resistant antimicrobial peptides

Antimicrobial host defence peptides: functions and clinical potential

(2020) Neeloffer Mookherjee et al.   NATURE REVIEWS DRUG DISCOVERY

Astragalus polysaccharides alleviates LPS‐induced inflammation via the NF‐κB/MAPK signaling pathway

(2020) Na Dong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Rational Avoidance of Protease Cleavage Sites and Symmetrical End-Tagging Significantly Enhances the Stability and Therapeutic Potential of Antimicrobial Peptides

(2020) Yongjie Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeted and Intracellular Antibacterial Activity against S. agalactiae of the Chimeric Peptides Based on Pheromone and Cell-Penetrating Peptides

(2020) Jiawei Li et al.   ACS Applied Materials & Interfaces

Antimicrobial Peptides with High Proteolytic Resistance for Combating Gram-Negative Bacteria

(2019) Jiajun Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens

(2019) Zhanyi Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Alternatives to Conventional Antibiotics in the Era of Antimicrobial Resistance

(2019) Chandradhish Ghosh et al.   TRENDS IN MICROBIOLOGY

The antimicrobial properties of the puroindolines, a review

(2019) Craig F. Morris   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Highly Stabilized α-Helical Coiled Coils Kill Gram-Negative Bacteria by Multicomplementary Mechanisms under Acidic Condition

(2019) Zhenheng Lai et al.   ACS Applied Materials & Interfaces

Current pharmaceutical developments in atopic dermatitis

(2019) Laurent Misery et al.   CURRENT OPINION IN PHARMACOLOGY

The Vast Structural Diversity of Antimicrobial Peptides

(2019) Johannes Koehbach et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Antimicrobial peptides with protease stability: progress and perspective

(2019) Changxuan Shao et al.   Future Medicinal Chemistry

Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

(2019) Rida Mourtada et al.   NATURE BIOTECHNOLOGY

Clinical Applications of Antimicrobial Peptides (AMPs): where do we stand now?

(2019) Divyashree M. et al.   PROTEIN AND PEPTIDE LETTERS

Bacterial Membrane Selective Antimicrobial Peptide-Mimetic Polyurethanes: Structure–Property Correlations and Mechanisms of Action

(2019) Steven Mankoci et al.   BIOMACROMOLECULES

The role of bacterial lipid diversity and membrane properties in modulating antimicrobial peptide activity and drug resistance

(2019) Tzong-Hsien Lee et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Simplified Head-to-Tail Cyclic Polypeptides as Biomaterial-Associated Antimicrobials with Endotoxin Neutralizing and Anti-Inflammatory Capabilities

(2019) Na Dong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antimicrobial peptides: Vestiges of past or modern therapeutics?

(2019) Jyotsna Bhatt Mitra et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors

(2019) Choi Yi Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multiple Strategy Optimization of Specifically Targeted Antimicrobial Peptide Based on Structure–Activity Relationships to Enhance Bactericidal Efficiency

(2019) Peng Tan et al.   ACS Biomaterials-Science & Engineering

Central β-turn increases the cell selectivity of imperfectly amphipathic α-helical peptides

(2018) Changxuan Shao et al.   Acta Biomaterialia

For the greater good: Programmed cell death in bacterial communities

(2018) Stijn H. Peeters et al.   MICROBIOLOGICAL RESEARCH

An engineered arginine-rich α-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice

(2018) Chin-Hao Yang et al.   Scientific Reports

Pse-T2, an Antimicrobial Peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-Resistant Pseudomonas aeruginosa Infection

(2018) Hee Kyoung Kang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold

(2017) Joakim E. Swedberg et al.   JOURNAL OF MEDICINAL CHEMISTRY

PREPARE: guidelines for planning animal research and testing

(2017) Adrian J Smith et al.   LABORATORY ANIMALS

Effects of Hydrophobic Amino Acid Substitutions on Antimicrobial Peptide Behavior

(2017) Kimberly D. Saint Jean et al.   Probiotics and Antimicrobial Proteins

Short, multiple-stranded β-hairpin peptides have antimicrobial potency with high selectivity and salt resistance

(2016) Shuli Chou et al.   Acta Biomaterialia

DifferentialIn VitroandIn VivoToxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis

(2016) Éanna Forde et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

(2016) Shu J. Lam et al.   Nature Microbiology

Characterization of antimicrobial activity and mechanisms of low amphipathic peptides with different α-helical propensity

(2015) Xin Zhu et al.   Acta Biomaterialia

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Importance of Tryptophan in Transforming an Amphipathic Peptide into a Pseudomonas aeruginosa-Targeted Antimicrobial Peptide

(2014) Xin Zhu et al.   PLoS One

Design of imperfectly amphipathic α-helical antimicrobial peptides with enhanced cell selectivity

(2013) Xin Zhu et al.   Acta Biomaterialia

Guanylated Polymethacrylates: A Class of Potent Antimicrobial Polymers with Low Hemolytic Activity

(2013) Katherine E. S. Locock et al.   BIOMACROMOLECULES

Twenty-first century mast cell stabilizers

(2013) D F Finn et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Inhibitory effects and mechanisms of physiological conditions on the activity of enantiomeric forms of an α-helical antibacterial peptide against bacteria

(2011) Jinfeng Huang et al.   PEPTIDES

Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents

(2010) Nikken Wiradharma et al.   BIOMATERIALS

Substrate-Guided Design of a Potent and Selective Kallikrein-Related Peptidase Inhibitor for Kallikrein 4

(2009) Joakim E. Swedberg et al.   CHEMISTRY & BIOLOGY

The Role of Hydrophobicity in the Antimicrobial and Hemolytic Activities of Polymethacrylate Derivatives

(2008) Kenichi Kuroda et al.   CHEMISTRY-A EUROPEAN JOURNAL