TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

Bladder tumor subtype commitment occurs in carcinoma in-situ driven by key signaling pathways including ECM remodeling

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TSPAN7 Exerts Anti-Tumor Effects in Bladder Cancer Through the PTEN/PI3K/AKT Pathway

(2021) Xi Yu et al.   Frontiers in Oncology

TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT

(2021) Zhengnan Huang et al.   OncoTargets and Therapy

Nuclear TEAD4 with SIX1 Overexpression is an Independent Prognostic Marker in the Stage I–III Colorectal Cancer

(2021) Tong Yu et al.   Cancer Management and Research

The oncogenic role of the cerebral endothelial cell adhesion molecule (CERCAM) in bladder cancer cells in vitro and in vivo

(2021) Yali Zuo et al.   Cancer Medicine

lncRNA ADAMTS9-AS1 promotes bladder cancer cell invasion, migration, and inhibits apoptosis and autophagy through PI3K/AKT/mTOR signaling pathway

(2021) Guoqing Yang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ID2 Inhibits Bladder Cancer Progression and Metastasis via PI3K/AKT Signaling Pathway

(2021) Weipu Mao et al.   Frontiers in Cell and Developmental Biology

PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway

(2020) Zhan Ma et al.   Aging-US

ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer

(2020) Jie Yao et al.   Aging-US

Guidelines and definitions for research on epithelial–mesenchymal transition

(2020) Jing Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overexpression of GAS6 Promotes Cell Proliferation and Invasion in Bladder Cancer by Activation of the PI3K/AKT Pathway

(2020) Shiyu Mao et al.   OncoTargets and Therapy

Galectin-1 Overexpression Activates the FAK/PI3K/AKT/mTOR Pathway and Is Correlated with Upper Urinary Urothelial Carcinoma Progression and Survival

(2020) Yu-Li Su et al.   Cells

Bladder Cancer

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FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

(2019) Ran Wei et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Context-dependent EMT programs in cancer metastasis

(2019) Nicole M. Aiello et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of TEAD Transcription Factors in Cancer Biology

(2019) Hyunbin D. Huh et al.   Cells

Metformin targets a YAP1-TEAD4 complex via AMPKα to regulate CCNE1/2 in bladder cancer cells

(2019) Yanju Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

An EMT‐related gene signature for the prognosis of human bladder cancer

(2019) Rui Cao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis

(2019) Joep J. de Jong et al.   Genome Medicine

TEAD4 exerts pro-metastatic effects and is negatively regulated by miR6839-3p in lung adenocarcinoma progression

(2018) Qun Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

(2018) Wei Zhang et al.   Cancer Cell International

Mesenchymal–epithelial transition in development and reprogramming

(2018) Duanqing Pei et al.   NATURE CELL BIOLOGY

Updated 2016 EAU Guidelines on Muscle-invasive and Metastatic Bladder Cancer

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EMT, cell plasticity and metastasis

(2016) Christine L. Chaffer et al.   CANCER AND METASTASIS REVIEWS

The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder Tumours

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Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK/PI3K/AKT signaling

(2016) P-F Zhang et al.   Cell Death & Disease

Increased TEAD4 expression and nuclear localization in colorectal cancer promote epithelial–mesenchymal transition and metastasis in a YAP-independent manner

(2015) Y Liu et al.   ONCOGENE

A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition

(2015) Wenting Xu et al.   Cell Adhesion & Migration

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis

(2015) Andrea Lunardi et al.   Oncotarget

Emerging roles of TEAD transcription factors and its coactivators in cancers

(2013) Ajaybabu V. Pobbati et al.   CANCER BIOLOGY & THERAPY

An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization

(2013) Tsukasa Shibue et al.   CANCER CELL

Cadherin Switching and Bladder Cancer

(2010) Richard T. Bryan et al.   JOURNAL OF UROLOGY

Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer

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Epithelial-Mesenchymal Transitions in Development and Disease

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