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Title
Modeling PCDH19-CE: From 2D Stem Cell Model to 3D Brain Organoids
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 7, Pages 3506
Publisher
MDPI AG
Online
2022-03-24
DOI
10.3390/ijms23073506
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Note: Only part of the references are listed.- Disrupted Excitatory Synaptic Contacts and Altered Neuronal Network Activity Underpins the Neurological Phenotype in PCDH19-Clustering Epilepsy (PCDH19-CE)
- (2021) Stefka Mincheva-Tasheva et al. MOLECULAR NEUROBIOLOGY
- Female-specific synaptic dysfunction and cognitive impairment in a mouse model of PCDH19 disorder
- (2021) Naosuke Hoshina et al. SCIENCE
- Dissecting the Role of PCDH19 in Clustering Epilepsy by Exploiting Patient-Specific Models of Neurogenesis
- (2021) Rossella Borghi et al. Journal of Clinical Medicine
- Human Blood Vessel Organoids Penetrate Human Cerebral Organoids and Form a Vessel-Like System
- (2021) Yujin Ahn et al. Cells
- Cerebral organoid and mouse models reveal a RAB39b–PI3K–mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes
- (2020) Wei Zhang et al. GENES & DEVELOPMENT
- Quantitative MRI-Based Analysis Identifies Developmental Limbic Abnormalities in PCDH19 Encephalopathy
- (2020) Matteo Lenge et al. CEREBRAL CORTEX
- Protocadherins at the Crossroad of Signaling Pathways
- (2020) Anna Pancho et al. Frontiers in Molecular Neuroscience
- Proximity-dependent proteomics reveals extensive interactions of Protocadherin-19 with regulators of Rho GTPases and the microtubule cytoskeleton
- (2020) Michelle R. Emond et al. NEUROSCIENCE
- Electrophysiological Maturation of Cerebral Organoids Correlates with Dynamic Morphological and Cellular Development
- (2020) Summer R. Fair et al. Stem Cell Reports
- Microfluidic reprogramming to pluripotency of human somatic cells
- (2019) Onelia Gagliano et al. Nature Protocols
- Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output
- (2019) Stefano L. Giandomenico et al. NATURE NEUROSCIENCE
- Schizophrenia is a later-onset feature of PCDH19 Girls Clustering Epilepsy
- (2019) Danique R. M. Vlaskamp et al. EPILEPSIA
- OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
- (2019) Ranjie Xu et al. Cell Stem Cell
- ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches
- (2019) Kevin Leandro et al. PHARMACOLOGICAL RESEARCH
- Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors
- (2019) Wei Zhang et al. Nature Communications
- Self-Organized Synchronous Calcium Transients in a Cultured Human Neural Network Derived from Cerebral Organoids
- (2019) Hideya Sakaguchi et al. Stem Cell Reports
- Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development
- (2019) Cleber A. Trujillo et al. Cell Stem Cell
- Engineering of human brain organoids with a functional vascular-like system
- (2019) Bilal Cakir et al. NATURE METHODS
- TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
- (2019) Xiaohui Lv et al. Nature Communications
- Autism-like behaviors in male mice with a Pcdh19 deletion
- (2019) Jisoo Lim et al. Molecular Brain
- Blood vessel formation in cerebral organoids formed from human embryonic stem cells
- (2019) Onju Ham et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PCDH19 -related epilepsy is associated with a broad neurodevelopmental spectrum
- (2018) Lacey Smith et al. EPILEPSIA
- PCDH19 -related epilepsy in a male with Klinefelter syndrome: Additional evidence supporting PCDH19 cellular interference disease mechanism
- (2018) Edward J. Romasko et al. EPILEPSY RESEARCH
- The female epilepsy protein PCDH19 is a new GABAAR-binding partner that regulates GABAergic transmission as well as migration and morphological maturation of hippocampal neurons
- (2018) Silvia Bassani et al. HUMAN MOLECULAR GENETICS
- A systematic review and meta-analysis of 271 PCDH19-variant individuals identifies psychiatric comorbidities, and association of seizure onset and disease severity
- (2018) Kristy L Kolc et al. MOLECULAR PSYCHIATRY
- PCDH19 regulation of neural progenitor cell differentiation suggests asynchrony of neurogenesis as a mechanism contributing to PCDH19 Girls Clustering Epilepsy
- (2018) Claire C. Homan et al. NEUROBIOLOGY OF DISEASE
- Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy
- (2018) Daniel T. Pederick et al. NEURON
- A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis
- (2018) Maria Ribecco-Lutkiewicz et al. Scientific Reports
- Defining the electroclinical phenotype and outcome of PCDH19-related epilepsy: A multicenter study
- (2018) Marina Trivisano et al. EPILEPSIA
- A mutation update for the PCDH19 gene causing early-onset epilepsy in females with an unusual expression pattern
- (2018) Rojeen Niazi et al. HUMAN MUTATION
- Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics
- (2018) Sonja Bergmann et al. Nature Protocols
- The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders
- (2017) H Chang et al. MOLECULAR PSYCHIATRY
- MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling
- (2017) N Mellios et al. MOLECULAR PSYCHIATRY
- Cell diversity and network dynamics in photosensitive human brain organoids
- (2017) Giorgia Quadrato et al. NATURE
- The use of brain organoids to investigate neural development and disease
- (2017) Elizabeth Di Lullo et al. NATURE REVIEWS NEUROSCIENCE
- Male patients affected by mosaic PCDH19 mutations: five new cases
- (2017) I. M. de Lange et al. NEUROGENETICS
- Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice
- (2017) Shuichi Hayashi et al. Scientific Reports
- Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection
- (2017) Momoko Watanabe et al. Cell Reports
- An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome
- (2017) Vira Iefremova et al. Cell Reports
- Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease
- (2017) Rui Li et al. Protein & Cell
- PCDH19-related epileptic encephalopathy in a male mosaic for a truncating variant
- (2016) Isabelle Thiffault et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening
- (2016) Ying I. Wang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure
- (2016) Xuyu Qian et al. CELL
- 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size
- (2016) Tomoki Otani et al. Cell Stem Cell
- PCDH19-related epilepsy in two mosaic male patients
- (2016) Alessandra Terracciano et al. EPILEPSIA
- Autism spectrum disorder phenotype and intellectual disability in females with epilepsy and PCDH-19 mutations
- (2016) Delphine Breuillard et al. EPILEPSY & BEHAVIOR
- A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
- (2016) M Fujitani et al. MOLECULAR PSYCHIATRY
- Effectiveness of antiepileptic therapy in patients with PCDH19 mutations
- (2016) Jan Lotte et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Pcdh19 Loss-of-Function Increases Neuronal Migration In Vitro but is Dispensable for Brain Development in Mice
- (2016) Daniel T. Pederick et al. Scientific Reports
- FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
- (2015) Jessica Mariani et al. CELL
- Using Patient-Derived Induced Pluripotent Stem Cells to Model and Treat Epilepsies
- (2015) Xixi Du et al. Current Neurology and Neuroscience Reports
- Protocadherins control the modular assembly of neuronal columns in the zebrafish optic tectum
- (2015) Sharon R. Cooper et al. JOURNAL OF CELL BIOLOGY
- The Blood–Brain Barrier
- (2015) Richard Daneman et al. Cold Spring Harbor Perspectives in Biology
- Characterizing PCDH19 in human induced pluripotent stem cells (iPSCs) and iPSC-derived developing neurons: emerging role of a protein involved in controlling polarity during neurogenesis
- (2015) Claudia Compagnucci et al. Oncotarget
- Protocadherin-17 Mediates Collective Axon Extension by Recruiting Actin Regulator Complexes to Interaxonal Contacts
- (2014) Shuichi Hayashi et al. DEVELOPMENTAL CELL
- Epilepsy and mental retardation restricted to females: X-linked epileptic infantile encephalopathy of unusual inheritance
- (2014) Kinga Duszyc et al. JOURNAL OF APPLIED GENETICS
- A comparison of non-integrating reprogramming methods
- (2014) Thorsten M Schlaeger et al. NATURE BIOTECHNOLOGY
- Generation of cerebral organoids from human pluripotent stem cells
- (2014) Madeline A Lancaster et al. Nature Protocols
- Correction: Sporadic Infantile Epileptic Encephalopathy Caused by Mutations in PCDH19 Resembles Dravet Syndrome but Mainly Affects Females
- (2014) Christel Depienne et al. PLoS Genetics
- Next-Generation Regenerative Medicine: Organogenesis from Stem Cells in 3D Culture
- (2013) Yoshiki Sasai Cell Stem Cell
- In vitro neurogenesis: development and functional implications of iPSC technology
- (2013) Claudia Compagnucci et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PCDH19-related female-limited epilepsy: Further details regarding early clinical features and therapeutic efficacy
- (2013) Norimichi Higurashi et al. EPILEPSY RESEARCH
- Protocadherin-18b interacts with Nap1 to control motor axon growth and arborization in zebrafish
- (2013) Sayantanee Biswas et al. MOLECULAR BIOLOGY OF THE CELL
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- Clinical and genetic aspects of PCDH19-related epilepsy syndromes and the possible role of PCDH19 mutations in males with autism spectrum disorders
- (2013) J. J. T. van Harssel et al. NEUROGENETICS
- Protocadherin 17 Regulates Presynaptic Assembly in Topographic Corticobasal Ganglia Circuits
- (2013) Naosuke Hoshina et al. NEURON
- Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95
- (2012) Nien-Pei Tsai et al. CELL
- PCDH19-related infantile epileptic encephalopathy: An unusual X-linked inheritance disorder
- (2012) Christel Depienne et al. HUMAN MUTATION
- Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier
- (2012) Leslie L Muldoon et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
- (2012) Ethan S Lippmann et al. NATURE BIOTECHNOLOGY
- Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
- (2012) Yichen Shi et al. NATURE NEUROSCIENCE
- Novel Animal Models of Pediatric Epilepsy
- (2012) Stéphane Auvin et al. Neurotherapeutics
- Cadherins in Brain Morphogenesis and Wiring
- (2012) Shinji Hirano et al. PHYSIOLOGICAL REVIEWS
- Modeling human cortical development in vitro using induced pluripotent stem cells
- (2012) J. Mariani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Spectrum of phenotypes in female patients with epilepsy due to protocadherin 19 mutations
- (2011) Nicola Specchio et al. EPILEPSIA
- A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion
- (2011) Michelle R. Emond et al. JOURNAL OF CELL BIOLOGY
- Mutations and deletions in PCDH19 account for various familial or isolated epilepsies in females
- (2010) Christel Depienne et al. HUMAN MUTATION
- Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation
- (2010) Sayantanee Biswas et al. JOURNAL OF CELL BIOLOGY
- Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia
- (2010) A Piton et al. MOLECULAR PSYCHIATRY
- Protocadherin 19 mutations in girls with infantile-onset epilepsy
- (2010) C. Marini et al. NEUROLOGY
- Specification of Region-Specific Neurons Including Forebrain Glutamatergic Neurons from Human Induced Pluripotent Stem Cells
- (2010) Hui Zeng et al. PLoS One
- Protocadherin-19 is essential for early steps in brain morphogenesis
- (2009) Michelle R. Emond et al. DEVELOPMENTAL BIOLOGY
- Epilepsy and mental retardation limited to females: an under-recognized disorder
- (2008) Ingrid E. Scheffer et al. BRAIN
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
- X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment
- (2008) Leanne M Dibbens et al. NATURE GENETICS
- CDK5RAP2 Is a Pericentriolar Protein That Functions in Centrosomal Attachment of the γ-Tubulin Ring Complex
- (2007) Ka-Wing Fong et al. MOLECULAR BIOLOGY OF THE CELL
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