The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells
Authors
Keywords
oxygen sensing, hypoxic signaling, posttranslational protein modification, Arginylation, arginyltransferase, ATE1, HIF1α, degradation, glycolysis, Warburg effect
Journal
DEVELOPMENTAL CELL
Volume 57, Issue 5, Pages 654-669.e9
Publisher
Elsevier BV
Online
2022-03-04
DOI
10.1016/j.devcel.2022.02.010
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The growing landscape of succinylation links metabolism and heart disease
- (2021) Lanting Yang et al. Epigenomics
- Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets
- (2020) Marike W. van Gisbergen et al. Frontiers in Oncology
- The Role of the Pentose Phosphate Pathway in Diabetes and Cancer
- (2020) Tongxin Ge et al. Frontiers in Endocrinology
- Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1
- (2020) Chunhua Jiang et al. Frontiers in Cell and Developmental Biology
- N-degron and C-degron pathways of protein degradation
- (2019) Alexander Varshavsky PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of Topological Parameters of Complex Disease Genes Reveals the Importance of Location in a Biomolecular Network
- (2019) Xiaohui Zhao et al. Genes
- Loss of the HIF pathway in a widely distributed intertidal crustacean, the copepodTigriopus californicus
- (2019) Allie M. Graham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
- (2019) Norma Masson et al. SCIENCE
- The last common ancestor of animals lacked the HIF pathway and respired in low-oxygen environments
- (2018) Daniel B Mills et al. eLife
- Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis
- (2018) Michael D. Birnbaum et al. ONCOGENE
- Target site specificity and in vivo complexity of the mammalian arginylome
- (2018) Junling Wang et al. Scientific Reports
- Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets
- (2017) Mark D. White et al. Nature Communications
- Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth
- (2017) Masaru Koido et al. Oncotarget
- Analysis of the relationship between coexpression domains and chromatin 3D organization
- (2017) María E. Soler-Oliva et al. PLoS Computational Biology
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Posttranslational arginylation enzyme Ate1 affects DNA mutagenesis by regulating stress response
- (2016) Akhilesh Kumar et al. Cell Death & Disease
- Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers
- (2015) R Rai et al. ONCOGENE
- Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase
- (2015) Fangliang Zhang et al. Nature Communications
- Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats
- (2014) Christopher S. Brower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule Pathway
- (2013) Christopher S. Brower et al. MOLECULAR CELL
- An archaeal origin of eukaryotes supports only two primary domains of life
- (2013) Tom A. Williams et al. NATURE
- The N-End Rule Pathway
- (2012) Takafumi Tasaki et al. Annual Review of Biochemistry
- A Heme-Sensing Mechanism in the Translational Regulation of Mitochondrial Cytochrome c Oxidase Biogenesis
- (2012) Iliana C. Soto et al. Cell Metabolism
- Arginylation-dependent regulation of a proteolytic product of talin is essential for cell–cell adhesion
- (2012) Fangliang Zhang et al. JOURNAL OF CELL BIOLOGY
- The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
- (2012) K. I. Piatkov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Evolution
- (2012) M. W. Gray Cold Spring Harbor Perspectives in Biology
- Dynamic Distribution of Linker Histone H1.5 in Cellular Differentiation
- (2012) Jing-Yu Li et al. PLoS Genetics
- Arginyltransferase Is an ATP-Independent Self-Regulating Enzyme that Forms Distinct Functional Complexes In Vivo
- (2011) Junling Wang et al. CHEMISTRY & BIOLOGY
- UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition
- (2011) Rasheda Sultana et al. EXPERIMENTAL CELL RESEARCH
- Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
- (2011) Jürgen Cox et al. JOURNAL OF PROTEOME RESEARCH
- Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization
- (2011) Francesco Licausi et al. NATURE
- Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants
- (2011) Daniel J. Gibbs et al. NATURE
- T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension
- (2011) P. Di Tommaso et al. NUCLEIC ACIDS RESEARCH
- Plant Oxygen Sensing Is Mediated by the N-End Rule Pathway: A Milestone in Plant Anaerobiosis
- (2011) R. Sasidharan et al. PLANT CELL
- The N-end rule pathway and regulation by proteolysis
- (2011) Alexander Varshavsky PROTEIN SCIENCE
- The arginylation-dependent association of calreticulin with stress granules is regulated by calcium
- (2010) Marcos A. Carpio et al. BIOCHEMICAL JOURNAL
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases
- (2010) Cheol-Sang Hwang et al. NATURE CELL BIOLOGY
- Differential Arginylation of Actin Isoforms Is Regulated by Coding Sequence-Dependent Degradation
- (2010) F. Zhang et al. SCIENCE
- Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
- (2009) Weibo Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
- (2009) Yair Benita et al. NUCLEIC ACIDS RESEARCH
- Role and regulation of prolyl hydroxylase domain proteins
- (2008) G-H Fong et al. CELL DEATH AND DIFFERENTIATION
- Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway
- (2008) Zanxian Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-Associated Factor, a Novel E3-Ubiquitin Ligase, Binds and Ubiquitinates Hypoxia-Inducible Factor 1 , Leading to Its Oxygen-Independent Degradation
- (2008) M. Y. Koh et al. MOLECULAR AND CELLULAR BIOLOGY
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started