- Home
- Publications
- Publication Search
- Publication Details
Title
The Role of the Pentose Phosphate Pathway in Diabetes and Cancer
Authors
Keywords
-
Journal
Frontiers in Endocrinology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-06-09
DOI
10.3389/fendo.2020.00365
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
- (2020) Federica Zatterale et al. Frontiers in Physiology
- Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis
- (2020) Na Tian et al. DIABETES
- Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance
- (2020) Kay H. M. Roumans et al. Nature Communications
- Cytoplasmic and Mitochondrial NADPH-Coupled Redox Systems in the Regulation of Aging
- (2019) Patrick Bradshaw Nutrients
- Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance
- (2019) Ruilong Liu et al. Nature Communications
- High glucose−induced ubiquitination of G6PD leads to the injury of podocytes
- (2019) Meng Wang et al. FASEB JOURNAL
- 6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming
- (2019) Hu Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Transketolase deficiency protects the liver from DNA damage by increasing levels of ribose 5-phosphate and nucleotides
- (2019) Minle Li et al. CANCER RESEARCH
- Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner
- (2019) Zhaoyu Qin et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Metabolic Signature of Macrophage Responses
- (2019) Antonella Viola et al. Frontiers in Immunology
- YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation
- (2019) Hao Sheng et al. CARCINOGENESIS
- Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes
- (2019) Maria Lytrivi et al. JOURNAL OF MOLECULAR BIOLOGY
- Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling
- (2019) Wei-Chen Yen et al. Redox Biology
- Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy
- (2018) Maura Knapp et al. ACTA PHARMACOLOGICA SINICA
- Pentose phosphate pathway activity parallels lipogenesis but not antioxidant processes in rat liver
- (2018) Eunsook S. Jin et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Prognostic significance of G6PD expression and localization in lung adenocarcinoma
- (2018) Ryo Nagashio et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Transcription factor YY1 promotes cell proliferation by directly activating the pentose phosphate pathway
- (2018) Shourong Wu et al. CANCER RESEARCH
- Reactive Oxygen Species in Metabolic and Inflammatory Signaling
- (2018) Steven J. Forrester et al. CIRCULATION RESEARCH
- Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation
- (2018) Xiaoyu Yang et al. Clinical & Translational Oncology
- Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
- (2018) Vignan Manne et al. Clinics in Liver Disease
- Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain
- (2018) Yu-Ting Chou et al. PLOS BIOLOGY
- Targeting Macrophages in Cancer: From Bench to Bedside
- (2018) Ashleigh R. Poh et al. Frontiers in Oncology
- Inhibiting 6-phosphogluconate dehydrogenase enhances chemotherapy efficacy in cervical cancer via AMPK-independent inhibition of RhoA and Rac1
- (2018) H. Guo et al. Clinical & Translational Oncology
- Modulation of G6PD affects bladder cancer via ROS accumulation and the AKT pathway in vitro
- (2018) Xiaoyi Chen et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer
- (2018) Subhamoy Dasgupta et al. NATURE
- Ribose-5-phosphate isomerase A overexpression promotes liver cancer development in transgenic zebrafish via activation of ERK and β-catenin pathways
- (2018) Yu-Ting Chou et al. CARCINOGENESIS
- Targeting macrophages: therapeutic approaches in cancer
- (2018) Luca Cassetta et al. NATURE REVIEWS DRUG DISCOVERY
- Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers
- (2018) Yi Ding et al. Nature Communications
- Inflammatory mechanisms linking obesity and metabolic disease
- (2017) Alan R. Saltiel et al. JOURNAL OF CLINICAL INVESTIGATION
- ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway
- (2017) Xin Yin et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells
- (2017) L Poulain et al. LEUKEMIA
- Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
- (2017) Oliver G McDonald et al. NATURE GENETICS
- Insulin action and resistance in obesity and type 2 diabetes
- (2017) Michael P Czech NATURE MEDICINE
- Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
- (2017) Yan Zheng et al. Nature Reviews Endocrinology
- Adapting to obesity with adipose tissue inflammation
- (2017) Shannon M. Reilly et al. Nature Reviews Endocrinology
- Mechanisms of the amplifying pathway of insulin secretion in the β cell
- (2017) Michael A. Kalwat et al. PHARMACOLOGY & THERAPEUTICS
- PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth
- (2017) Xiumei Zhang et al. Cell Death & Disease
- Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway
- (2017) Xiaoyu Ma et al. Nature Communications
- Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome
- (2017) Adrián Benito et al. Oncotarget
- G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3
- (2017) Qiao Zhang et al. Oncotarget
- Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung Cancer
- (2017) Wujian Zheng et al. Frontiers in Pharmacology
- The role of glucose-6-phosphate dehydrogenase in adipose tissue inflammation in obesity
- (2017) Yoon Jeong Park et al. Adipocyte
- Molecular mechanisms of ROS production and oxidative stress in diabetes
- (2016) P. Newsholme et al. BIOCHEMICAL JOURNAL
- Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes
- (2016) Junjian Wang et al. CANCER LETTERS
- Transketolase counteracts oxidative stress to drive cancer development
- (2016) Iris Ming-Jing Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis
- (2016) Marta Anna Kowalik et al. Oncotarget
- SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation
- (2016) Shuang-Nian Xu et al. Scientific Reports
- Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle
- (2016) Robert S. Lee-Young et al. Molecular Metabolism
- Mechanism of ER Stress and Inflammation for Hepatic Insulin Resistance in Obesity
- (2015) Ok-Kyung Kim et al. ANNALS OF NUTRITION AND METABOLISM
- Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
- (2015) Rachel J. Perry et al. CELL
- Glucose-6-phosphate dehydrogenase expression is correlated with poor clinical prognosis in esophageal squamous cell carcinoma
- (2015) Xin Wang et al. EJSO
- MicroRNA-124 Reduces the Pentose Phosphate Pathway and Proliferation by Targeting PRPS1 and RPIA mRNAs in Human Colorectal Cancer Cells
- (2015) Zhaoping Qiu et al. GASTROENTEROLOGY
- iTRAQ-based quantitative proteomic analysis of cervical cancer
- (2015) YIBING DING et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells
- (2015) Mourad Ferdaoussi et al. JOURNAL OF CLINICAL INVESTIGATION
- 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
- (2015) Ruiting Lin et al. NATURE CELL BIOLOGY
- Regulation of metabolism by the innate immune system
- (2015) Denise E. Lackey et al. Nature Reviews Endocrinology
- O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth
- (2015) Xiongjian Rao et al. Nature Communications
- BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas
- (2015) De-Hui Kong et al. Oncotarget
- Time and Demand are Two Critical Dimensions of Immunometabolism: The Process of Macrophage Activation and the Pentose Phosphate Pathway
- (2015) Csörsz Nagy et al. Frontiers in Immunology
- Structure and functioning mechanism of transketolase
- (2014) German A. Kochetov et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
- (2014) Anna Stincone et al. BIOLOGICAL REVIEWS
- Ribose-5-phosphate isomerase A regulates hepatocarcinogenesisviaPP2A and ERK signaling
- (2014) Shih-Ci Ciou et al. INTERNATIONAL JOURNAL OF CANCER
- Lysine Acetylation Activates 6-Phosphogluconate Dehydrogenase to Promote Tumor Growth
- (2014) Changliang Shan et al. MOLECULAR CELL
- Quantitative flux analysis reveals folate-dependent NADPH production
- (2014) Jing Fan et al. NATURE
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met
- (2013) Barden Chan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release
- (2013) Peter Spégel et al. BIOCHEMICAL JOURNAL
- A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation
- (2013) Peng Jiang et al. CELL CYCLE
- PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis
- (2013) Xuehui Hong et al. GUT
- Macrophage Glucose-6-Phosphate Dehydrogenase Stimulates Proinflammatory Responses with Oxidative Stress
- (2013) M. Ham et al. MOLECULAR AND CELLULAR BIOLOGY
- TAp73 enhances the pentose phosphate pathway and supports cell proliferation
- (2013) Wenjing Du et al. NATURE CELL BIOLOGY
- Role of Glutathione in Cancer Progression and Chemoresistance
- (2013) Nicola Traverso et al. Oxidative Medicine and Cellular Longevity
- Adipokines and Hepatic Insulin Resistance
- (2013) Yu Li et al. Journal of Diabetes Research
- Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
- (2012) Taro Hitosugi et al. CANCER CELL
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- PGC-1α Improves Glucose Homeostasis in Skeletal Muscle in an Activity-Dependent Manner
- (2012) Serge Summermatter et al. DIABETES
- The Effects of Long-Term Oral Benfotiamine Supplementation on Peripheral Nerve Function and Inflammatory Markers in Patients With Type 1 Diabetes: A 24-month, double-blind, randomized, placebo-controlled trial
- (2012) D. A. Fraser et al. DIABETES CARE
- The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate
- (2012) Chiara Riganti et al. FREE RADICAL BIOLOGY AND MEDICINE
- Glucose-6-phosphate dehydrogenase, NADPH, and cell survival
- (2012) Robert C. Stanton IUBMB LIFE
- Proteomic analysis of gastric cancer and immunoblot validation of potential biomarkers
- (2012) Nina Kočevar WORLD JOURNAL OF GASTROENTEROLOGY
- Identification of transaldolase as a novel serum biomarker for hepatocellular carcinoma metastasis using xenografted mouse model and clinic samples
- (2011) Cun Wang et al. CANCER LETTERS
- Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy
- (2011) N. Rabbani et al. DIABETES OBESITY & METABOLISM
- G6PD Up-Regulation Promotes Pancreatic β-Cell Dysfunction
- (2011) Joo-Won Lee et al. ENDOCRINOLOGY
- p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
- (2011) Peng Jiang et al. NATURE CELL BIOLOGY
- Overexpression of G6PD is associated with poor clinical outcome in gastric cancer
- (2011) Jixu Wang et al. TUMOR BIOLOGY
- The Insulin Receptor: A New Target for Cancer Therapy
- (2011) Roberta Malaguarnera et al. Frontiers in Endocrinology
- Fructose Induces Transketolase Flux to Promote Pancreatic Cancer Growth
- (2010) H. Liu et al. CANCER RESEARCH
- Oxidative Stress and Diabetic Complications
- (2010) Ferdinando Giacco et al. CIRCULATION RESEARCH
- Vitamin B1 Analog Benfotiamine Prevents Diabetes-Induced Diastolic Dysfunction and Heart Failure Through Akt/Pim-1–Mediated Survival Pathway
- (2010) Rajesh G. Katare et al. Circulation-Heart Failure
- A Double-Blind, Randomized, Placebo-Controlled Clinical Trial on Benfotiamine Treatment in Patients With Diabetic Nephropathy
- (2010) A. Alkhalaf et al. DIABETES CARE
- Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Promotes Skeletal Muscle Lipid Refuelingin Vivoby Activatingde NovoLipogenesis and the Pentose Phosphate Pathway
- (2010) Serge Summermatter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming
- (2010) F Zhao et al. ONCOGENE
- High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and β-cell apoptosis
- (2009) Zhaoyun Zhang et al. FASEB JOURNAL
- Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver
- (2009) Rakhee S. Gupte et al. FREE RADICAL BIOLOGY AND MEDICINE
- Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29
- (2009) Pedro Vizán et al. INTERNATIONAL JOURNAL OF CANCER
- Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine
- (2009) Robert Hanczko et al. JOURNAL OF CLINICAL INVESTIGATION
- High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study
- (2008) N. Rabbani et al. DIABETOLOGIA
- Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells
- (2008) Xiaojun Xu et al. INTERNATIONAL JOURNAL OF CANCER
- The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: A review
- (2008) M. M. C. Wamelink et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Fine-Needle Aspiration of Thyroid Nodules: Proteomic Analysis To Identify Cancer Biomarkers
- (2008) Laura Giusti et al. JOURNAL OF PROTEOME RESEARCH
- Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
- (2008) Adilson Guilherme et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now