Tumor-stroma TGF-β1-THBS2 feedback circuit drives pancreatic ductal adenocarcinoma progression via integrin αvβ3/CD36-mediated activation of the MAPK pathway
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Title
Tumor-stroma TGF-β1-THBS2 feedback circuit drives pancreatic ductal adenocarcinoma progression via integrin αvβ3/CD36-mediated activation of the MAPK pathway
Authors
Keywords
Cancer-associated fibroblasts, Thrombospondin 2, Tumor–stromal cell communication, Integrin α, v, β, 3, /CD36-MAPK cascade, Tumor progression
Journal
CANCER LETTERS
Volume 528, Issue -, Pages 59-75
Publisher
Elsevier BV
Online
2021-12-25
DOI
10.1016/j.canlet.2021.12.025
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