- Home
- Publications
- Publication Search
- Publication Details
Title
Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis
Authors
Keywords
Pancreatic Cancer, Desmoplasia, Fibrosis, Stellate cells, Extracellular matrix, Tumor microenvironment
Journal
Molecular Cancer
Volume 18, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-01-21
DOI
10.1186/s12943-018-0927-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A phase I dose escalation trial of nab-paclitaxel and fixed dose radiation in patients with unresectable or borderline resectable pancreatic cancer
- (2018) Jacob E. Shabason et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transition
- (2018) Yanbin Ma et al. CANCER LETTERS
- Surgery after FOLFIRINOX treatment for locally advanced and borderline resectable pancreatic cancer: increase in tumour attenuation on CT correlates with R0 resection
- (2018) Giovanni Marchegiani et al. EUROPEAN RADIOLOGY
- MiR-21-mediated Metabolic Alteration of Cancer-associated Fibroblasts and Its Effect on Pancreatic Cancer Cell Behavior
- (2018) Shuo Chen et al. International Journal of Biological Sciences
- Phase I/II trial of pimasertib plus gemcitabine in patients with metastatic pancreatic cancer
- (2018) Eric Van Cutsem et al. INTERNATIONAL JOURNAL OF CANCER
- Ruxolitinib + capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies
- (2018) Herbert Hurwitz et al. INVESTIGATIONAL NEW DRUGS
- Involvement of partial EMT in cancer progression
- (2018) Masao Saitoh JOURNAL OF BIOCHEMISTRY
- Dual role of Par-4 in abrogation of EMT and switching on Mesenchymal to Epithelial Transition (MET) in metastatic pancreatic cancer cells
- (2018) Archana Katoch et al. MOLECULAR CARCINOGENESIS
- Targeting the tumour stroma to improve cancer therapy
- (2018) Kenneth C. Valkenburg et al. Nature Reviews Clinical Oncology
- Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells
- (2018) Kei Takahashi et al. ONCOGENE
- Tumor Hypoxia As an Enhancer of Inflammation-Mediated Metastasis: Emerging Therapeutic Strategies
- (2018) Josh W. DiGiacomo et al. Targeted Oncology
- Mutations in BRCA1, BRCA2, and PALB2, and a panel of 50 cancer-associated genes in pancreatic ductal adenocarcinoma
- (2018) Shoko Takeuchi et al. Scientific Reports
- Diels Alder-mediated release of gemcitabine from hybrid nanoparticles for enhanced pancreatic cancer therapy
- (2017) Adeolu Oluwasanmi et al. JOURNAL OF CONTROLLED RELEASE
- Thermally triggered theranostics for pancreatic cancer therapy
- (2017) Maryam Malekigorji et al. Nanoscale
- The Tissue Factor Pathway and Wound Healing
- (2017) Maureane Hoffman SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions
- (2017) Orianne Olivares et al. Nature Communications
- Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis
- (2017) Keiichi Asano et al. Scientific Reports
- Development of a Gemcitabine-Polymer Conjugate with Prolonged Cytotoxicity against a Pancreatic Cancer Cell Line
- (2017) Fanny Joubert et al. ACS Macro Letters
- Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
- (2017) A J Rice et al. Oncogenesis
- Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth
- (2016) Sounik Saha et al. ACS Nano
- Matrix control of pancreatic cancer: New insights into fibronectin signaling
- (2016) Mary Topalovski et al. CANCER LETTERS
- Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer
- (2016) Christian Bauer et al. CANCER LETTERS
- Key role of pancreatic stellate cells in pancreatic cancer
- (2016) Srinivasa P. Pothula et al. CANCER LETTERS
- TGF Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis
- (2016) D. R. Principe et al. CANCER RESEARCH
- Stromal dynamic reciprocity in cancer: intricacies of fibroblastic-ECM interactions
- (2016) Jennifer Alexander et al. CURRENT OPINION IN CELL BIOLOGY
- Pancreatic cancer
- (2016) Terumi Kamisawa et al. LANCET
- A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
- (2016) Faiyaz Notta et al. NATURE
- Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
- (2016) Shawn M Davidson et al. NATURE MEDICINE
- Tumor microenvironment: Sanctuary of the devil
- (2015) Lanlan Hui et al. CANCER LETTERS
- Ormeloxifene Suppresses Desmoplasia and Enhances Sensitivity of Gemcitabine in Pancreatic Cancer
- (2015) Sheema Khan et al. CANCER RESEARCH
- Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
- (2015) J. J. Kamphorst et al. CANCER RESEARCH
- Parenterally administrable nano-micelles of 3,4-difluorobenzylidene curcumin for treating pancreatic cancer
- (2015) Prashant Kesharwani et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Assessing the Significance of BRCA1 and BRCA2 Mutations in Pancreatic Cancer
- (2015) Julia Carnevale et al. JOURNAL OF CLINICAL ONCOLOGY
- Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer
- (2015) Daniel V.T. Catenacci et al. JOURNAL OF CLINICAL ONCOLOGY
- Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine
- (2015) Ming-Chen Yang et al. Molecular Cancer
- Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer
- (2015) Suniti Misra et al. Frontiers in Immunology
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- Neutralizing Murine TGF R2 Promotes a Differentiated Tumor Cell Phenotype and Inhibits Pancreatic Cancer Metastasis
- (2014) K. T. Ostapoff et al. CANCER RESEARCH
- Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
- (2014) L. Rahib et al. CANCER RESEARCH
- Pancreatic stellate cells and pancreas cancer: Current perspectives and future strategies
- (2014) Jonathan Haqq et al. EUROPEAN JOURNAL OF CANCER
- Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer
- (2014) J. Al Shemaili et al. EUROPEAN JOURNAL OF CANCER
- Drug Resistance in Cancer: An Overview
- (2014) Genevieve Housman et al. Cancers
- Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells
- (2013) S. Kozono et al. CANCER RESEARCH
- The tumor microenvironment at a glance
- (2013) F. R. Balkwill et al. JOURNAL OF CELL SCIENCE
- Novel Curcumin-Loaded Magnetic Nanoparticles for Pancreatic Cancer Treatment
- (2013) M. M. Yallapu et al. MOLECULAR CANCER THERAPEUTICS
- The epigenetics of epithelial-mesenchymal plasticity in cancer
- (2013) Wai Leong Tam et al. NATURE MEDICINE
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Expression of vascular endothelial growth factor and epidermal growth factor receptor in pancreatic ductal adenocarcinomas, neuroendocrine tumours and chronic pancreatitis
- (2013) Adrian Saftoiu et al. Endoscopic Ultrasound
- Tumour basement membrane laminin expression predicts outcome following curative resection of pancreatic head cancer
- (2012) J A van der Zee et al. BRITISH JOURNAL OF CANCER
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition
- (2012) KARL QUINT et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The extracellular matrix: A dynamic niche in cancer progression
- (2012) Pengfei Lu et al. JOURNAL OF CELL BIOLOGY
- Pivotal role of the CCL5/CCR5 interaction for recruitment of endothelial progenitor cells in mouse wound healing
- (2012) Yuko Ishida et al. JOURNAL OF CLINICAL INVESTIGATION
- Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
- (2012) Meredith A. Collins et al. JOURNAL OF CLINICAL INVESTIGATION
- Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans
- (2012) Atsuo Ochi et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor
- (2012) Daiki Eguchi et al. JOURNAL OF SURGICAL RESEARCH
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
- (2012) Mert Erkan et al. Nature Reviews Gastroenterology & Hepatology
- Developments in metastatic pancreatic cancer: Is gemcitabine still the standard?
- (2012) Jie-Er Ying WORLD JOURNAL OF GASTROENTEROLOGY
- Survival after Resection of Pancreatic Adenocarcinoma: Results from a Single Institution over Three Decades
- (2011) Jordan M. Winter et al. ANNALS OF SURGICAL ONCOLOGY
- Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression
- (2011) Mario A. Shields et al. BIOCHEMICAL JOURNAL
- Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence
- (2011) Carmen Guerra et al. CANCER CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Oncogenic transcription factors: cornerstones of inflammation-linked pancreatic carcinogenesis
- (2011) Sandra Baumgart et al. GUT
- StellaTUM: current consensus and discussion on pancreatic stellate cell research
- (2011) Mert Erkan et al. GUT
- Tenascin-C Enhances Pancreatic Cancer Cell Growth and Motility and Affects Cell Adhesion through Activation of the Integrin Pathway
- (2011) Igor Paron et al. PLoS One
- Current Treatment Options for Pancreatic Carcinoma
- (2011) Emily Castellanos et al. Current Oncology Reports
- Transforming growth factor β-induced epithelial-mesenchymal transition increases cancer stem-like cells in the PANC-1 cell line
- (2011) HUI WANG et al. Oncology Letters
- Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis
- (2010) Zhihong Xu et al. AMERICAN JOURNAL OF PATHOLOGY
- Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells
- (2010) Kazuhiro Kikuta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Carcinomas Contain a Matrix Metalloproteinase–Resistant Isoform of Type I Collagen Exerting Selective Support to Invasion
- (2010) Elena Makareeva et al. CANCER RESEARCH
- Dynamic interplay between the collagen scaffold and tumor evolution
- (2010) Mikala Egeblad et al. CURRENT OPINION IN CELL BIOLOGY
- Tracking Down the Hedgehog's Lair in the Pancreas
- (2010) Anirban Maitra GASTROENTEROLOGY
- CXCL17 and ICAM2 Are Associated With a Potential Anti-Tumor Immune Response in Early Intraepithelial Stages of Human Pancreatic Carcinogenesis
- (2010) Nobuyoshi Hiraoka et al. GASTROENTEROLOGY
- CCK1 and CCK2 Receptors Are Expressed on Pancreatic Stellate Cells and Induce Collagen Production
- (2010) Marc J. Berna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stressing the role of O-GlcNAc: linking cell survival to keratin modification
- (2010) Jeremy D. Rotty et al. NATURE CELL BIOLOGY
- Cytoskeletal keratin glycosylation protects epithelial tissue from injury
- (2010) Nam-On Ku et al. NATURE CELL BIOLOGY
- In Vitro and In Vivo Anticancer Activity of a Novel Nano-sized Formulation Based on Self-assembling Polymers Against Pancreatic Cancer
- (2010) Clare Hoskins et al. PHARMACEUTICAL RESEARCH
- Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1α heterozygous-null mice after burn wounding
- (2010) Xianjie Zhang et al. WOUND REPAIR AND REGENERATION
- Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas
- (2009) Eugenia Mato et al. BIOCHEMICAL JOURNAL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Roles of Pancreatic Stellate Cells in Pancreatic Inflammation and Fibrosis
- (2009) Atsushi Masamune et al. Clinical Gastroenterology and Hepatology
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Controlled and targeted tumor chemotherapy by ultrasound-activated nanoemulsions/microbubbles
- (2009) Natalya Y. Rapoport et al. JOURNAL OF CONTROLLED RELEASE
- The Extracellular Matrix: Not Just Pretty Fibrils
- (2009) R. O. Hynes SCIENCE
- Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer
- (2008) Atsushi Masamune et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Pancreatic Cancer
- (2008) Anirban Maitra et al. Annual Review of Pathology-Mechanisms of Disease
- Pancreatic Stellate Cells and Pancreatic Cancer Cells: An Unholy Alliance
- (2008) A. Vonlaufen et al. CANCER RESEARCH
- Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
- (2008) R. F. Hwang et al. CANCER RESEARCH
- Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression
- (2008) Naoki Itano et al. CANCER SCIENCE
- The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma
- (2008) Mert Erkan et al. Clinical Gastroenterology and Hepatology
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
- (2008) S. Jones et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now