Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

(2017) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of stromal cancer-associated fibroblasts in pancreatic cancer

(2017) Dagny von Ahrens et al.   Journal of Hematology & Oncology

Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts

(2017) Josep Baulida   Molecular Oncology

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

(2017) Anna Labernadie et al.   NATURE CELL BIOLOGY

DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster

(2016) S. Zagorac et al.   CANCER RESEARCH

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

(2016) Mieke Buck et al.   CURRENT MEDICINAL CHEMISTRY

Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

(2016) Yong Hu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition

(2016) Esther Ekpe-Adewuyi et al.   Oncotarget

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells

(2016) Sören V. Siegmund et al.   PLoS One

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

(2015) Richard A Moffitt et al.   NATURE GENETICS

Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation

(2015) Daoxiang Zhang et al.   Cell Reports

PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells

(2015) Ernst J.A. Steller et al.   NEOPLASIA

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma

(2014) Andrew D. Rhim et al.   CANCER CELL

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

(2014) Nina Cabezas-Wallscheid et al.   Cell Stem Cell

Fibroblast heterogeneity in the cancer wound

(2014) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis and are targets of metastasis-inducing S100A4

(2014) M T Hansen et al.   ONCOGENE

Deletion of Serum Amyloid A3 Improves High Fat High Sucrose Diet-Induced Adipose Tissue Inflammation and Hyperlipidemia in Female Mice

(2014) Laura J. den Hartigh et al.   PLoS One

Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis

(2014) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stromal response to Hedgehog signaling restrains pancreatic cancer progression

(2014) J. J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis

(2014) Vladimir Riabov et al.   Frontiers in Physiology

Non-Cell-Autonomous Tumor Suppression by p53

(2013) Amaia Lujambio et al.   CELL

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of Normal and Cancer-associated Fibroblasts from Fresh Tissues by Fluorescence Activated Cell Sorting (FACS)

(2013) Yoray Sharon et al.   Jove-Journal of Visualized Experiments

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

(2012) Michael A Jacobetz et al.   GUT

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

Tumor Engraftment in Nude Mice and Enrichment in Stroma- Related Gene Pathways Predict Poor Survival and Resistance to Gemcitabine in Patients with Pancreatic Cancer

(2011) I. Garrido-Laguna et al.   CLINICAL CANCER RESEARCH

Serum Amyloid A Activates the NLRP3 Inflammasome and Promotes Th17 Allergic Asthma in Mice

(2011) J. L. Ather et al.   JOURNAL OF IMMUNOLOGY

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Gr-1+CD11b+ Myeloid Cells Tip the Balance of Immune Protection to Tumor Promotion in the Premetastatic Lung

(2010) H. H. Yan et al.   CANCER RESEARCH

Expression of Serum Amyloid A in Human Ovarian Epithelial Tumors: Implication for a Role in Ovarian Tumorigenesis

(2010) Simcha Urieli-Shoval et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A

(2010) Carmela De Santo et al.   NATURE IMMUNOLOGY

Pancreatic Cancer

(2010) Manuel Hidalgo   NEW ENGLAND JOURNAL OF MEDICINE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment

(2009) Yongping Crawford et al.   CANCER CELL

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

Regulation of Serum Amyloid A3 (SAA3) in Mouse Colonic Epithelium and Adipose Tissue by the Intestinal Microbiota

(2009) Christopher S. Reigstad et al.   PLoS One

Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity

(2009) B. J. Quinn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Serum amyloid A: An acute-phase protein involved in tumour pathogenesis

(2008) E. Malle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pancreatic Cancer Stem Cells: Implications for the Treatment of Pancreatic Cancer

(2008) D. M. Simeone   CLINICAL CANCER RESEARCH

Serum amyloid A-induced IL-6 production by rheumatoid synoviocytes

(2008) Tomohiro Koga et al.   FEBS LETTERS

The adipokine SAA3 is induced by interleukin-1β in mouse adipocytes

(2008) Grit Sommer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY