Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Biology of Bone Metastases in Prostate Cancer

(2016) Janine Hensel et al.   UROLOGY

Microdissecting the role of microRNAs in the pathogenesis of prostate cancer

(2015) Shiekh Gazalla Ayub et al.   Cancer Genetics

Integrin  v 6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2

(2014) A. Dutta et al.   CANCER RESEARCH

Recent advances in bone-targeted therapies of metastatic prostate cancer

(2014) Xiyun Deng et al.   CANCER TREATMENT REVIEWS

The complexity of miRNA-mediated repression

(2014) A Wilczynska et al.   CELL DEATH AND DIFFERENTIATION

Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically induced multistep skin carcinogenesis

(2014) Rainer Kunstfeld et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Secretome Profiling of Primary Cells Reveals That THBS2 Is a Salivary Biomarker of Oral Cavity Squamous Cell Carcinoma

(2014) Chia-Wei Hsu et al.   JOURNAL OF PROTEOME RESEARCH

Managing bone metastases and reducing skeletal related events in prostate cancer

(2014) Benjamin A. Gartrell et al.   Nature Reviews Clinical Oncology

The Host Microenvironment Influences Prostate Cancer Invasion, Systemic Spread, Bone Colonization, and Osteoblastic Metastasis

(2014) Sourik S. Ganguly et al.   Frontiers in Oncology

Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2

(2013) Xiaojian Ni et al.   CANCER SCIENCE

Estrogen receptor α in cancer-associated fibroblasts suppresses prostate cancer invasion via modulation of thrombospondin 2 and matrix metalloproteinase 3

(2013) Spencer Slavin et al.   CARCINOGENESIS

Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells

(2013) Yuan-Li Huang et al.   CELLULAR SIGNALLING

MicroRNA-376c Inhibits Cell Proliferation and Invasion in Osteosarcoma by Targeting to Transforming Growth Factor-Alpha

(2013) Yi Jin et al.   DNA AND CELL BIOLOGY

Expression analysis of thrombospondin 2 in prostate cancer and benign prostatic hyperplasia

(2013) A.R. Matos et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Roles of microRNAs during prostatic tumorigenesis and tumor progression

(2013) Y-X Fang et al.   ONCOGENE

MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells

(2013) A Formosa et al.   ONCOGENE

Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2

(2013) P. R. Lawler et al.   Cold Spring Harbor Perspectives in Medicine

SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells

(2012) Jenna D. Lovaas et al.   PROSTATE

Thrombospondin-1 Triggers Cell Migration and Development of Advanced Prostate Tumors

(2011) V. Firlej et al.   CANCER RESEARCH

MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance

(2011) G. Ye et al.   JOURNAL OF CELL SCIENCE

Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis

(2010) Conor C. Lynch   BONE

CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo

(2010) Manuel Koch et al.   BREAST CANCER RESEARCH AND TREATMENT

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Thrombospondins: from structure to therapeutics

(2008) S. Kazerounian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES