Nanovaccines with cell-derived components for cancer immunotherapy

Advances in the development of personalized neoantigen-based therapeutic cancer vaccines

(2021) Eryn Blass et al.   Nature Reviews Clinical Oncology

In situ poly I:C released from living cell drug nanocarriers for macrophage-mediated antitumor immunotherapy

(2021) Haimei Zhou et al.   BIOMATERIALS

Nanobiomaterial-based vaccination immunotherapy of cancer

(2021) Fangmin Chen et al.   BIOMATERIALS

Ultrasound-Mediated Remotely Controlled Nanovaccine Delivery for Tumor Vaccination and Individualized Cancer Immunotherapy

(2021) Zhouqi Meng et al.   NANO LETTERS

Immune Cell Membrane‐Coated Biomimetic Nanoparticles for Targeted Cancer Therapy

(2021) Fatemeh Oroojalian et al.   Small

Recent Advances in Cell Membrane‐Derived Biomimetic Nanotechnology for Cancer Immunotherapy

(2021) Faisal Raza et al.   Advanced Healthcare Materials

Cytosolic Delivery of Thiolated Neoantigen Nano‐Vaccine Combined with Immune Checkpoint Blockade to Boost Anti‐Cancer T Cell Immunity

(2021) Da Zhang et al.   Advanced Science

Gene silencing-mediated immune checkpoint blockade for tumor therapy boosted by dendrimer-entrapped gold nanoparticles

(2021) Xue Xue et al.   Science China-Materials

Nanovaccine‐Based Strategies to Overcome Challenges in the Whole Vaccination Cascade for Tumor Immunotherapy

(2021) Lin Qin et al.   Small

Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors

(2021) Baharak Bahmani et al.   Nature Communications

Recent Progress in Dendritic Cell-Based Cancer Immunotherapy

(2021) Kazuhiko Matsuo et al.   Cancers

Advanced biomaterials for cancer immunotherapy

(2020) Fan Yang et al.   ACTA PHARMACOLOGICA SINICA

A Hybrid Eukaryotic-Prokaryotic Nanoplatform with Photothermal Modality for Enhanced Antitumor Vaccination

(2020) Qi Chen et al.   ADVANCED MATERIALS

Tumor cell membrane‐coated liquid metal nanovaccine for tumor prevention

(2020) Yu Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

(2020) John D. Martin et al.   Nature Reviews Clinical Oncology

Artificial Mini Dendritic Cells Boost T Cell–Based Immunotherapy for Ovarian Cancer

(2020) Shanshan Cheng et al.   Advanced Science

Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses

(2020) Yu Chao et al.   Science Advances

Copresentation of Tumor Antigens and Costimulatory Molecules via Biomimetic Nanoparticles for Effective Cancer Immunotherapy

(2020) Junning Ma et al.   NANO LETTERS

Human chimeric antigen receptor macrophages for cancer immunotherapy

(2020) Michael Klichinsky et al.   NATURE BIOTECHNOLOGY

A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

(2020) Qianqian Ni et al.   Science Advances

Improving Cancer Immunotherapy by Cell Membrane‐Camouflaged Nanoparticles

(2020) Ziling Zeng et al.   ADVANCED FUNCTIONAL MATERIALS

Engineering autologous tumor cell vaccine to locally mobilize antitumor immunity in tumor surgical bed

(2020) Lei Fang et al.   Science Advances

Engineered Nanoparticles for Cancer Vaccination and Immunotherapy

(2020) Marisa E. Aikins et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bacterial Vesicle-Cancer Cell Hybrid Membrane-Coated Nanoparticles for Tumor Specific Immune Activation and Photothermal Therapy

(2020) Dongdong Wang et al.   ACS Applied Materials & Interfaces

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery

(2020) Yuqiong Xia et al.   ADVANCED MATERIALS

Tumor cell membrane enveloped aluminum phosphate nanoparticles for enhanced cancer vaccination

(2020) Jingyao Gan et al.   JOURNAL OF CONTROLLED RELEASE

Proton-driven transformable nanovaccine for cancer immunotherapy

(2020) Ningqiang Gong et al.   Nature Nanotechnology

Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

(2020) Lang Rao et al.   Nature Communications

An implantable blood clot–based immune niche for enhanced cancer vaccination

(2020) Qin Fan et al.   Science Advances

PEI-modified macrophage cell membrane-coated PLGA nanoparticles encapsulating Dendrobium polysaccharides as a vaccine delivery system for ovalbumin to improve immune responses

(2020) Zhiqiang Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Nanoparticle-Enhanced Radiotherapy to Trigger Robust Cancer Immunotherapy

(2019) Qian Chen et al.   ADVANCED MATERIALS

Nanoparticle‐Based Nanomedicines to Promote Cancer Immunotherapy: Recent Advances and Future Directions

(2019) Jianping Liu et al.   Small

Expandable Immunotherapeutic Nanoplatforms Engineered from Cytomembranes of Hybrid Cells Derived from Cancer and Dendritic Cells

(2019) Wen‐Long Liu et al.   ADVANCED MATERIALS

Cancer Cell Membrane Camouflaged Nanoprobe for Catalytic Ratiometric Photoacoustic Imaging of MicroRNA in Living Mice

(2019) Kai Zhang et al.   ADVANCED MATERIALS

Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy

(2019) Eliran Moshe Reuven et al.   ACS Nano

Cancer Cell Membrane Camouflaged Nanoparticles to Realize Starvation Therapy Together with Checkpoint Blockades for Enhancing Cancer Therapy

(2019) Wei Xie et al.   ACS Nano

Surface-Layer Protein-Enhanced Immunotherapy Based on Cell Membrane-Coated Nanoparticles for the Effective Inhibition of Tumor Growth and Metastasis

(2019) Min Wu et al.   ACS Applied Materials & Interfaces

Human Cancer Cell Membrane-Coated Biomimetic Nanoparticles Reduce Fibroblast-Mediated Invasion and Metastasis and Induce T-Cells

(2019) Jiefu Jin et al.   ACS Applied Materials & Interfaces

Oriented Assembly of Cell-Mimicking Nanoparticles via a Molecular Affinity Strategy for Targeted Drug Delivery

(2019) Jing Xie et al.   ACS Nano

Light‐Triggered In Situ Gelation to Enable Robust Photodynamic‐Immunotherapy by Repeated Stimulations

(2019) Zhouqi Meng et al.   ADVANCED MATERIALS

Iron Nanoparticles for Low-power Local Magnetic Hyperthermia in Combination with Immune Checkpoint Blockade for Systemic Antitumor Therapy

(2019) Yu Chao et al.   NANO LETTERS

Advances in therapeutic applications of extracellular vesicles

(2019) Oscar P. B. Wiklander et al.   Science Translational Medicine

Engineering Magnetosomes for High-Performance Cancer Vaccination

(2019) Feng Li et al.   ACS Central Science

Biomimetic Nanotechnology toward Personalized Vaccines

(2019) Jiarong Zhou et al.   ADVANCED MATERIALS

Immunomodulatory Lipocomplex Functionalized with Photosensitizer-Embedded Cancer Cell Membrane Inhibits Tumor Growth and Metastasis

(2019) Han Young Kim et al.   NANO LETTERS

Nanovaccines for cancer immunotherapy

(2019) Yu Zhang et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

(2019) Wen-Long Liu et al.   Nature Communications

Cancer cell membrane coated silica nanoparticles loaded with ICG for tumour specific photothermal therapy of osteosarcoma

(2019) Jingwei Zhang et al.   Artificial Cells Nanomedicine and Biotechnology

Multiantigenic Nanoformulations Activate Anticancer Immunity Depending on Size

(2019) Shengxian Li et al.   ADVANCED FUNCTIONAL MATERIALS

Engineering patient-specific cancer immunotherapies

(2019) Lindsay Scheetz et al.   Nature Biomedical Engineering

Engineering anti-cancer nanovaccine based on antigen cross-presentation

(2019) Vaishnavi U. Warrier et al.   BIOSCIENCE REPORTS

Red blood cell–derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy

(2019) Xiao Han et al.   Science Advances

Recent Advances in Nanovaccines Using Biomimetic Immunomodulatory Materials

(2019) Vijayan et al.   Pharmaceutics

In situ thermal ablation of tumors in combination with nano-adjuvant and immune checkpoint blockade to inhibit cancer metastasis and recurrence

(2019) Xiao Han et al.   BIOMATERIALS

Artificially cloaked viral nanovaccine for cancer immunotherapy

(2019) Manlio Fusciello et al.   Nature Communications

Cancer Cell Membrane-Coated Adjuvant Nanoparticles with Mannose Modification for Effective Anticancer Vaccination

(2018) Rong Yang et al.   ACS Nano

Erythrocyte–Cancer Hybrid Membrane Camouflaged Hollow Copper Sulfide Nanoparticles for Prolonged Circulation Life and Homotypic-Targeting Photothermal/Chemotherapy of Melanoma

(2018) Dongdong Wang et al.   ACS Nano

Remote-Loaded Platelet Vesicles for Disease-Targeted Delivery of Therapeutics

(2018) Man Ying et al.   ADVANCED FUNCTIONAL MATERIALS

Platelet-Leukocyte Hybrid Membrane-Coated Immunomagnetic Beads for Highly Efficient and Highly Specific Isolation of Circulating Tumor Cells

(2018) Lang Rao et al.   ADVANCED FUNCTIONAL MATERIALS

A Cisplatin-Loaded Immunochemotherapeutic Nanohybrid Bearing Immune Checkpoint Inhibitors for Enhanced Cervical Cancer Therapy

(2018) Na Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances of Membrane-Cloaked Nanoplatforms for Biomedical Applications

(2018) Xiangzhao Ai et al.   BIOCONJUGATE CHEMISTRY

Red Blood Cells as Smart Delivery Systems

(2018) Xiao Han et al.   BIOCONJUGATE CHEMISTRY

A Universal Approach to Render Nanomedicine with Biological Identity Derived from Cell Membranes

(2018) Jingyi Zhu et al.   BIOMACROMOLECULES

Extracellular vesicles in cancer — implications for future improvements in cancer care

(2018) Rong Xu et al.   Nature Reviews Clinical Oncology

Interleukin-6: designing specific therapeutics for a complex cytokine

(2018) Christoph Garbers et al.   NATURE REVIEWS DRUG DISCOVERY

Personalized vaccines for cancer immunotherapy

(2018) Ugur Sahin et al.   SCIENCE

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors

(2018) Tingting Wang et al.   Nature Communications

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

(2018) Naohiro Seo et al.   Nature Communications

Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway

(2018) Tsing-Lee Tang-Huau et al.   Nature Communications

Platelet-camouflaged nanococktail: Simultaneous inhibition of drug-resistant tumor growth and metastasis via a cancer cells and tumor vasculature dual-targeting strategy

(2018) Lijia Jing et al.   Theranostics

Elimination of established tumors with nanodisc-based combination chemoimmunotherapy

(2018) Rui Kuai et al.   Science Advances

Towards superior dendritic-cell vaccines for cancer therapy

(2018) Mansi Saxena et al.   Nature Biomedical Engineering

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

M1 Macrophage-Derived Nanovesicles Potentiate the Anticancer Efficacy of Immune Checkpoint Inhibitors

(2018) Yeon Woong Choo et al.   ACS Nano

PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy

(2018) Lukasz J. Ochyl et al.   BIOMATERIALS

Biomaterial-assisted targeted modulation of immune cells in cancer treatment

(2018) Hua Wang et al.   NATURE MATERIALS

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

(2018) Marco Ruella et al.   NATURE MEDICINE

Cancer cell membrane-cloaked mesoporous silica nanoparticles with a pH-sensitive gatekeeper for cancer treatment

(2018) Chang-Ming Liu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Erythrocyte-cancer hybrid membrane-camouflaged melanin nanoparticles for enhancing photothermal therapy efficacy in tumors

(2018) Qin Jiang et al.   BIOMATERIALS

Synthetic nanovaccines for immunotherapy

(2017) Min Luo et al.   JOURNAL OF CONTROLLED RELEASE

Exosomes from M1-Polarized Macrophages Potentiate the Cancer Vaccine by Creating a Pro-inflammatory Microenvironment in the Lymph Node

(2017) Lifang Cheng et al.   MOLECULAR THERAPY

Nanobiotechnology: Cell membrane-based delivery systems

(2017) Pengfei Zhang et al.   Nano Today

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Cellular uptake and trafficking of antisense oligonucleotides

(2017) Stanley T Crooke et al.   NATURE BIOTECHNOLOGY

A STING-activating nanovaccine for cancer immunotherapy

(2017) Min Luo et al.   Nature Nanotechnology

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

(2017) Jeff E. Grotzke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management

(2017) Soracha Thamphiwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response

(2017) Oh Youn Kim et al.   Nature Communications

Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma

(2017) Liya Zhu et al.   Theranostics

Synergistic Chemo–Photothermal Therapy of Breast Cancer by Mesenchymal Stem Cell-Encapsulated Yolk–Shell GNR@HPMO-PTX Nanospheres

(2016) Jiang Wu et al.   ACS Applied Materials & Interfaces

Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer

(2016) Haiqiang Cao et al.   ACS Nano

Cancer Cell Membrane-Coated Gold Nanocages with Hyperthermia-Triggered Drug Release and Homotypic Target Inhibit Growth and Metastasis of Breast Cancer

(2016) Huiping Sun et al.   ADVANCED FUNCTIONAL MATERIALS

Nanoparticles camouflaged in platelet membrane coating as an antibody decoy for the treatment of immune thrombocytopenia

(2016) Xiaoli Wei et al.   BIOMATERIALS

Cancer immunotherapy: the beginning of the end of cancer?

(2016) Sofia Farkona et al.   BMC Medicine

Dendritic cell-based immunotherapy

(2016) Rachel L Sabado et al.   CELL RESEARCH

Dendritic Cell-Based Immunotherapy: State of the Art and Beyond

(2016) K. F. Bol et al.   CLINICAL CANCER RESEARCH

Dendritic cell–derived exosomes for cancer therapy

(2016) Jonathan M. Pitt et al.   JOURNAL OF CLINICAL INVESTIGATION

Polymeric capsule-cushioned leukocyte cell membrane vesicles as a biomimetic delivery platform

(2016) Changyong Gao et al.   Nanoscale

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

(2016) Alexander S. Cheung et al.   Small

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma

(2015) Yuanyuan Guo et al.   ACS Nano

Anticancer Platelet-Mimicking Nanovehicles

(2015) Quanyin Hu et al.   ADVANCED MATERIALS

Outer membrane vesicles as platform vaccine technology

(2015) Leo van der Pol et al.   Biotechnology Journal

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Exosomes as nanocarriers for immunotherapy of cancer and inflammatory diseases

(2015) Thanh-Huyen Tran et al.   CLINICAL IMMUNOLOGY

Therapeutic cancer vaccines

(2015) Cornelis J.M. Melief et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Cell membrane-camouflaged nanoparticles for drug delivery

(2015) Brian T. Luk et al.   JOURNAL OF CONTROLLED RELEASE

Programmed co-delivery of paclitaxel and doxorubicin boosted by camouflaging with erythrocyte membrane

(2015) Qiang Fu et al.   Nanoscale

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Injectable cryogel-based whole-cell cancer vaccines

(2015) Sidi A. Bencherif et al.   Nature Communications

Cell or Cell Membrane-Based Drug Delivery Systems

(2015) Songwei Tan et al.   Theranostics

Outer membrane vesicles as platform vaccine technology

(2015) Leo van der Pol et al.   Biotechnology Journal

Exosomes as Immunotheranostic Nanoparticles

(2014) Natasha G et al.   CLINICAL THERAPEUTICS

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Large-scale generation of cell-derived nanovesicles

(2014) W. Jo et al.   Nanoscale

Therapeutic vaccines for cancer: an overview of clinical trials

(2014) Ignacio Melero et al.   Nature Reviews Clinical Oncology

Bacterial Outer Membrane Vesicles and Vaccine Applications

(2014) Reinaldo Acevedo et al.   Frontiers in Immunology

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

Advances in targeting cell surface signalling molecules for immune modulation

(2013) Sheng Yao et al.   NATURE REVIEWS DRUG DISCOVERY

Cyclic di-AMP: another second messenger enters the fray

(2013) Rebecca M. Corrigan et al.   NATURE REVIEWS MICROBIOLOGY

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Allogeneic tumor cell vaccines

(2013) Sanjay Srivatsan et al.   Human Vaccines & Immunotherapeutics

Fusions between dendritic cells and whole tumor cells as anticancer vaccines

(2013) Shigeo Koido et al.   OncoImmunology

Exosomes are endogenous nanoparticles that can deliver biological information between cells

(2012) Dongmei Sun et al.   ADVANCED DRUG DELIVERY REVIEWS

Functional transfer of microRNA by exosomes

(2012) W. Stoorvogel   BLOOD

Whole Cell Vaccines—Past Progress and Future Strategies

(2012) Bridget P. Keenan et al.   SEMINARS IN ONCOLOGY

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Adjuvants for Enhancing the Immunogenicity of Whole Tumor Cell Vaccines

(2011) Cheryl Lai-Lai Chiang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

A New Theranostic System Based on Gold Nanocages and Phase-Change Materials with Unique Features for Photoacoustic Imaging and Controlled Release

(2011) Geon Dae Moon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

How platelets safeguard vascular integrity

(2011) B. HO-TIN-NOÉ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

(2011) Makoto Mitsunaga et al.   NATURE MEDICINE

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

Drug delivery by red blood cells: vascular carriers designed by mother nature

(2010) Vladimir R Muzykantov   Expert Opinion on Drug Delivery

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

(2010) J. J. Woodward et al.   SCIENCE

Whole tumor antigen vaccines

(2010) Cheryl Lai-Lai Chiang et al.   SEMINARS IN IMMUNOLOGY

CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases

(2009) Dennis M. Klinman et al.   ADVANCED DRUG DELIVERY REVIEWS

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

(2009) Jörg Vollmer et al.   ADVANCED DRUG DELIVERY REVIEWS

Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant

(2008) C. R. Casella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES