Gene silencing-mediated immune checkpoint blockade for tumor therapy boosted by dendrimer-entrapped gold nanoparticles

GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ

(2020) Hasan Onur Dikmen et al.   Journal of Neuroinflammation

Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release

(2019) Shu Lian et al.   EBioMedicine

Silencing PD-1 and PD-L1 with nanoparticle-delivered small interfering RNA increases cytotoxicity of tumor-infiltrating lymphocytes

(2019) Yanheng Wu et al.   Nanomedicine

Label-Free Fluorescent Poly(amidoamine) Dendrimer for Traceable and Controlled Drug Delivery

(2019) Guoying Wang et al.   BIOMACROMOLECULES

Zwitterion-functionalized dendrimer-entrapped gold nanoparticles for serum-enhanced gene delivery to inhibit cancer cell metastasis

(2019) Zhijuan Xiong et al.   Acta Biomaterialia

Dual-Blockade Immune Checkpoint for Breast Cancer Treatment Based on a Tumor-Penetrating Peptide Assembling Nanoparticle

(2019) Guorui Li et al.   ACS Applied Materials & Interfaces

UTMD-Promoted Co-Delivery of Gemcitabine and miR-21 Inhibitor by Dendrimer-Entrapped Gold Nanoparticles for Pancreatic Cancer Therapy

(2018) Lizhou Lin et al.   Theranostics

Enhanced Delivery of Therapeutic siRNA into Glioblastoma Cells Using Dendrimer-Entrapped Gold Nanoparticles Conjugated with β-Cyclodextrin

(2018) Jieru Qiu et al.   Nanomaterials

Efficient PD-L1 gene silence promoted by hyaluronidase for cancer immunotherapy

(2018) Xiuwen Guan et al.   JOURNAL OF CONTROLLED RELEASE

Development and characterization of heparin-immobilized polycaprolactone nanofibrous scaffolds for tissue engineering using gamma-irradiation

(2017) Jin-Oh Jeong et al.   RSC Advances

Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma

(2016) Curtis A. Clark et al.   CANCER RESEARCH

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

(2016) Dangge Wang et al.   NANO LETTERS

Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody

(2016) Chao Wang et al.   NANO LETTERS

Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination

(2016) Celine Boutros et al.   Nature Reviews Clinical Oncology

Dendrimer-entrapped gold nanoparticles modified with β-cyclodextrin for enhanced gene delivery applications

(2016) Jieru Qiu et al.   RSC Advances

Dendrimer-Stabilized Gold Nanostars as a Multifunctional Theranostic Nanoplatform for CT Imaging, Photothermal Therapy, and Gene Silencing of Tumors

(2016) Ping Wei et al.   Advanced Healthcare Materials

Partially PEGylated dendrimer-entrapped gold nanoparticles: a promising nanoplatform for highly efficient DNA and siRNA delivery

(2016) Wenxiu Hou et al.   Journal of Materials Chemistry B

RGD Peptide-Modified Dendrimer-Entrapped Gold Nanoparticles Enable Highly Efficient and Specific Gene Delivery to Stem Cells

(2015) Lingdan Kong et al.   ACS Applied Materials & Interfaces

Partially Acetylated Dendrimer-Entrapped Gold Nanoparticles with Reduced Cytotoxicity for Gene Delivery Applications

(2015) Wenxiu Hou et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Ovarian Cancer Immunotherapy Using PD-L1 siRNA Targeted Delivery from Folic Acid-Functionalized Polyethylenimine: Strategies to Enhance T Cell Killing

(2015) Pei Yun Teo et al.   Advanced Healthcare Materials

Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles

(2014) Jingyi Zhu et al.   BIOMATERIALS

Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies

(2014) G. K. Philips et al.   INTERNATIONAL IMMUNOLOGY

Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer--Response

(2013) M. Sznol et al.   CLINICAL CANCER RESEARCH

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Dendrimer-entrapped gold nanoparticles modified with folic acid for targeted gene delivery applications

(2013) Tongyu Xiao et al.   Biomaterials Science

Gene delivery using dendrimer-entrapped gold nanoparticles as nonviral vectors

(2012) Yuebin Shan et al.   BIOMATERIALS

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation

(2012) Willemijn Hobo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

(2012) Suzanne L Topalian et al.   CURRENT OPINION IN IMMUNOLOGY

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo

(2011) A. M. Paterson et al.   JOURNAL OF IMMUNOLOGY

The Novel Costimulatory Programmed Death Ligand 1/B7.1 Pathway Is Functional in Inhibiting Alloimmune Responses In Vivo

(2011) J. Yang et al.   JOURNAL OF IMMUNOLOGY

siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells

(2010) W. Hobo et al.   BLOOD

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

(2010) J.-J. Park et al.   BLOOD

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

A comparative study of the functionalization of mesoporous silica MCM-41 by deposition of 3-aminopropyltrimethoxysilane from toluene and from the vapor phase

(2009) Hanna Ritter et al.   MICROPOROUS AND MESOPOROUS MATERIALS