Tumor Microenvironment-Responsive Yolk–Shell NaCl@Virus-Inspired Tetrasulfide-Organosilica for Ion-Interference Therapy via Osmolarity Surge and Oxidative Stress Amplification

Nitric Oxide Modulating Calcium Store for Ca 2+ ‐Initiated Cancer Therapy

(2021) Xu Chu et al.   ADVANCED FUNCTIONAL MATERIALS

Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice

(2021) Julia Wagner et al.   ACS Nano

Ultrafast Directional Janus Pt–Mesoporous Silica Nanomotors for Smart Drug Delivery

(2021) Paula Díez et al.   ACS Nano

Membrane Interactions of Virus-like Mesoporous Silica Nanoparticles

(2021) Sara Malekkhaiat Häffner et al.   ACS Nano

Nanomedicine Enables Drug-Potency Activation with Tumor Sensitivity and Hyperthermia Synergy in the Second Near-Infrared Biowindow

(2021) Weiwei Liu et al.   ACS Nano

Polyethylenimine-Modified Mesoporous Silica Nanoparticles Induce a Survival Mechanism in Vascular Endothelial Cells via Microvesicle-Mediated Autophagosome Release

(2021) Lu Zhang et al.   ACS Nano

A Tumor‐Microenvironment‐Responsive Nanocomposite for Hydrogen Sulfide Gas and Trimodal‐Enhanced Enzyme Dynamic Therapy

(2021) Bin Liu et al.   ADVANCED MATERIALS

GSH-Responsive Nanoprodrug to Inhibit Glycolysis and Alleviate Immunosuppression for Cancer Therapy

(2021) Xiaohan Liu et al.   NANO LETTERS

A pH-targeted and NIR-responsive NaCl-nanocarrier for photothermal therapy and ion-interference therapy

(2021) Chen Ma et al.   Nanomedicine-Nanotechnology Biology and Medicine

One-Step Integration of Tumor Microenvironment-Responsive Calcium and Copper Peroxides Nanocomposite for Enhanced Chemodynamic/Ion-Interference Therapy

(2021) Bin Liu et al.   ACS Nano

Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy

(2020) Xiaohui Chen et al.   ACS Nano

Supramolecular Assemblies of Heterogeneous Mesoporous Silica Nanoparticles to Co-deliver Antimicrobial Peptides and Antibiotics for Synergistic Eradication of Pathogenic Biofilms

(2020) Qilin Yu et al.   ACS Nano

Highly Stable Iron Carbonyl Complex Delivery Nanosystem for Improving Cancer Therapy

(2020) Xiao-Shuang Wang et al.   ACS Nano

Self-Delivery Photo-Immune Stimulators for Photodynamic Sensitized Tumor Immunotherapy

(2020) Lin-Ping Zhao et al.   ACS Nano

Virus-like hollow mesoporous silica nanoparticles for cancer combination therapy

(2020) Dajun Xu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Tumor targeted combination therapy mediated by functional macrophages under fluorescence imaging guidance

(2020) Yan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Ascorbate Tumor Chemotherapy by An Iron-Engineered Nanomedicine-Catalyzed Tumor-Specific Pro-Oxidation

(2020) Bowen Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Na2S2O8 Nanoparticles Trigger Antitumor Immunotherapy through Reactive Oxygen Species Storm and Surge of Tumor Osmolarity

(2020) Yang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion channels as lipid sensors: from structures to mechanisms

(2020) Mackenzie J. Thompson et al.   Nature Chemical Biology

Calcium-Overload-Mediated Tumor Therapy by Calcium Peroxide Nanoparticles

(2019) Meng Zhang et al.   Chem

NaCl Nanoparticles as a Cancer Therapeutic

(2019) Wen Jiang et al.   ADVANCED MATERIALS

Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy

(2019) Yang Li et al.   ACS Nano

Functional Nanoparticles with a Reducible Tetrasulfide Motif to Upregulate mRNA Translation and Enhance Transfection in Hard-to-Transfect Cells

(2019) Yue Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrasmall mesoporous organosilica nanoparticles: Morphology modulations and redox-responsive biodegradability for tumor-specific drug delivery

(2018) Luodan Yu et al.   BIOMATERIALS

Oxygen Activation and Energy Conservation by Cytochrome c Oxidase

(2018) Mårten Wikström et al.   CHEMICAL REVIEWS

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

(2018) Michael M. Gaschler et al.   Nature Chemical Biology

Two-dimensional Na–Cl crystals of unconventional stoichiometries on graphene surface from dilute solution at ambient conditions

(2018) Guosheng Shi et al.   Nature Chemistry

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

(2018) Kuangda Lu et al.   Nature Biomedical Engineering

Gadolinium-Encapsulated Graphene Carbon Nanotheranostics for Imaging-Guided Photodynamic Therapy

(2018) Hongmin Chen et al.   ADVANCED MATERIALS

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

(2018) Shuaifei Wang et al.   ACS Nano

Self-Assembled Copper–Amino Acid Nanoparticles for in Situ Glutathione “AND” H2O2 Sequentially Triggered Chemodynamic Therapy

(2018) Baojin Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Partial PEGylation of superparamagnetic iron oxide nanoparticles thinly coated with amine-silane as a source of ultrastable tunable nanosystems for biomedical applications

(2017) Manuel Cano et al.   Nanoscale

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations

(2017) Nathalie Busschaert et al.   Nature Chemistry

Facile Synthesis of Uniform Virus-like Mesoporous Silica Nanoparticles for Enhanced Cellular Internalization

(2017) Wenxing Wang et al.   ACS Central Science

The role of glycine in regulated cell death

(2016) Joel M. Weinberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Large-Pore Ultrasmall Mesoporous Organosilica Nanoparticles: Micelle/Precursor Co-templating Assembly and Nuclear-Targeted Gene Delivery

(2014) Meiying Wu et al.   ADVANCED MATERIALS

Anisotropic Growth-Induced Synthesis of Dual-Compartment Janus Mesoporous Silica Nanoparticles for Bimodal Triggered Drugs Delivery

(2014) Xiaomin Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

(2014) Sung-Kyun Ko et al.   Nature Chemistry

Nanoparticles Mimicking Viral Surface Topography for Enhanced Cellular Delivery

(2013) Yuting Niu et al.   ADVANCED MATERIALS

Zinc and zinc transporters in prostate carcinogenesis

(2013) Vladimir Kolenko et al.   Nature Reviews Urology

Induction of Inflammasome-dependent Pyroptosis by Carbon Black Nanoparticles

(2011) Anna C. Reisetter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sodium Overload and Water Influx Activate the NALP3 Inflammasome

(2010) Christine Schorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metalloproteins and metal sensing

(2009) Kevin J. Waldron et al.   NATURE

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY