Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

Electron Crystallography Reveals Atomic Structures of Metal–Organic Nanoplates with M12(μ3-O)8(μ3-OH)8(μ2-OH)6 (M = Zr, Hf) Secondary Building Units

(2017) Ruihan Dai et al.   INORGANIC CHEMISTRY

Metal–Organic Nanosheets Formed via Defect-Mediated Transformation of a Hafnium Metal–Organic Framework

(2017) Matthew J. Cliffe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designing nanomedicine for immuno-oncology

(2017) Wen Jiang et al.   Nature Biomedical Engineering

The Emerging Role of B Cells in Tumor Immunity

(2016) Peiling Tsou et al.   CANCER RESEARCH

Olsalazine-Based Metal–Organic Frameworks as Biocompatible Platforms for H2 Adsorption and Drug Delivery

(2016) Dana J. Levine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

(2016) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Immune-priming of the Tumor Microenvironment by Radiotherapy

(2015) Vafa Shahabi et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Abscopal effects of radiation therapy: A clinical review for the radiobiologist

(2015) Shankar Siva et al.   CANCER LETTERS

The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant

(2015) Kobe Reynders et al.   CANCER TREATMENT REVIEWS

Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications

(2015) Kenneth K. Ng et al.   CHEMICAL REVIEWS

Nanomedicine Applications of Hybrid Nanomaterials Built from Metal–Ligand Coordination Bonds: Nanoscale Metal–Organic Frameworks and Nanoscale Coordination Polymers

(2015) Chunbai He et al.   CHEMICAL REVIEWS

Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma

(2015) Marta Garnelo et al.   GUT

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

IgM-Dependent Phagocytosis in Microglia Is Mediated by Complement Receptor 3, Not Fc /  Receptor

(2015) J. R. Weinstein et al.   JOURNAL OF IMMUNOLOGY

Nanoscintillator-Mediated X-ray Inducible Photodynamic Therapy for In Vivo Cancer Treatment

(2015) Hongmin Chen et al.   NANO LETTERS

Abstract 5023: Synergistic antitumor effects of combinatorial immune checkpoint inhibition with anti-PD-1/PD-L antibodies and the IDO pathway inhibitors NLG-919 and indoximod in the context of active immunotherapy

(2015) Mario R. Mautino et al.   CANCER RESEARCH

Optimized Metal–Organic-Framework Nanospheres for Drug Delivery: Evaluation of Small-Molecule Encapsulation

(2014) Jia Zhuang et al.   ACS Nano

Synergistic Assembly of Heavy Metal Clusters and Luminescent Organic Bridging Ligands in Metal–Organic Frameworks for Highly Efficient X-ray Scintillation

(2014) Cheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleic Acid–Metal Organic Framework (MOF) Nanoparticle Conjugates

(2014) William Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoscale Metal–Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer

(2014) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Porphyrin–phospholipid liposomes permeabilized by near-infrared light

(2014) Kevin A. Carter et al.   Nature Communications

The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma

(2014) Minghui Li et al.   Journal for ImmunoTherapy of Cancer

Immune Modulation in Cancer with Antibodies

(2013) David B. Page et al.   Annual Review of Medicine

Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift

(2013) Silvia C. Formenti et al.   JNCI-Journal of the National Cancer Institute

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

The Chemistry and Applications of Metal-Organic Frameworks

(2013) H. Furukawa et al.   SCIENCE

Synthesis, Structure, and Metalation of Two New Highly Porous Zirconium Metal–Organic Frameworks

(2012) William Morris et al.   INORGANIC CHEMISTRY

Proof of concept for next-generation nanoparticle drugs in humans

(2012) Cormac Sheridan   NATURE BIOTECHNOLOGY

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

(2012) Michael A. Postow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

(2011) Jonathan F. Lovell et al.   NATURE MATERIALS

Photodynamic therapy: illuminating the road from cell death towards anti-tumour immunity

(2010) Abhishek D. Garg et al.   APOPTOSIS

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

(2010) X. Liu et al.   BLOOD

Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer

(2010) Robert Timmerman   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CD20+ B Cells: The Other Tumor-Infiltrating Lymphocytes

(2010) B. H. Nelson   JOURNAL OF IMMUNOLOGY

Long-Term Results of Hypofractionated Radiation Therapy for Breast Cancer

(2010) Timothy J. Whelan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model

(2009) Eddy W. Yue et al.   JOURNAL OF MEDICINAL CHEMISTRY

Systemic effects of local radiotherapy

(2009) Silvia C Formenti et al.   LANCET ONCOLOGY

Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape

(2008) Jessica B. Katz et al.   IMMUNOLOGICAL REVIEWS

Exceptional Behavior over the Whole Adsorption−Storage−Delivery Cycle for NO in Porous Metal Organic Frameworks

(2008) Alistair C. McKinlay et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY