Functional Nanoparticles with a Reducible Tetrasulfide Motif to Upregulate mRNA Translation and Enhance Transfection in Hard-to-Transfect Cells

Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy

(2018) Yannan Yang et al.   ADVANCED FUNCTIONAL MATERIALS

Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies

(2018) Spencer C. Knight et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy

(2018) Yao Lu et al.   BIOMATERIALS

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters

(2018) Colin J. McKinlay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

Debugging Nano–Bio Interfaces: Systematic Strategies to Accelerate Clinical Translation of Nanotechnologies

(2018) Morteza Mahmoudi   TRENDS IN BIOTECHNOLOGY

Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance

(2018) Yue Wang et al.   Journal of Materials Chemistry B

Optimization of a Degradable Polymer–Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells

(2018) James C. Kaczmarek et al.   NANO LETTERS

Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles

(2018) Hanzey Yasar et al.   JOURNAL OF NANOBIOTECHNOLOGY

Decreases in GSH:GSSG activate vascular endothelial growth factor receptor 2 (VEGFR2) in human aortic endothelial cells

(2018) Priya K. Prasai et al.   Redox Biology

Dendrimer-Based Lipid Nanoparticles Deliver Therapeutic FAH mRNA to Normalize Liver Function and Extend Survival in a Mouse Model of Hepatorenal Tyrosinemia Type I

(2018) Qiang Cheng et al.   ADVANCED MATERIALS

Addressing the autofluorescence issue in deep tissue imaging by two-photon microscopy: the significance of far-red emitting dyes

(2017) Yong Woong Jun et al.   Chemical Science

Tools for translation: non-viral materials for therapeutic mRNA delivery

(2017) Khalid A. Hajj et al.   Nature Reviews Materials

Structure-Dependent and Glutathione-Responsive Biodegradable Dendritic Mesoporous Organosilica Nanoparticles for Safe Protein Delivery

(2016) Yannan Yang et al.   CHEMISTRY OF MATERIALS

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

(2015) J. Yun et al.   SCIENCE

Large-Pore Ultrasmall Mesoporous Organosilica Nanoparticles: Micelle/Precursor Co-templating Assembly and Nuclear-Targeted Gene Delivery

(2014) Meiying Wu et al.   ADVANCED MATERIALS

Chemical Basis of Interactions Between Engineered Nanoparticles and Biological Systems

(2014) Qingxin Mu et al.   CHEMICAL REVIEWS

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration

(2014) Liu Yang et al.   Nature Communications

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: A randomized, double-blind, placebo-controlled trial

(2012) Zhi-Wei Lai et al.   ARTHRITIS AND RHEUMATISM