Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice

Direct Transfer of Mesoporous Silica Nanoparticles between Macrophages and Cancer Cells

(2020) Stefan Franco et al.   Cancers

Harnessing the immune system to fight cancer with Toll-like receptor and RIG-I-like receptor agonists

(2019) Carole Bourquin et al.   PHARMACOLOGICAL RESEARCH

Polymer-Coated Gold Nanospheres Do Not Impair the Innate Immune Function of Human B Lymphocytes in Vitro

(2019) Sandra Hočevar et al.   ACS Nano

Degradable Drug Carriers: Vanishing Mesoporous Silica Nanoparticles

(2019) Karin Möller et al.   CHEMISTRY OF MATERIALS

Development of resiquimod-loaded modified PLA-based nanoparticles for cancer immunotherapy: A kinetic study

(2019) Cédric Thauvin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Engineered hybrid spider silk particles as delivery system for peptide vaccines

(2018) Matthias Lucke et al.   BIOMATERIALS

Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy

(2018) Hyunjoon Kim et al.   BIOMATERIALS

Polymer-based nanoparticles loaded with a TLR7 ligand to target the lymph node for immunostimulation

(2018) Jérôme Widmer et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Personalized vaccines for cancer immunotherapy

(2018) Ugur Sahin et al.   SCIENCE

Peptide Amphiphile Micelle Vaccine Size and Charge Influence the Host Antibody Response

(2018) Rui Zhang et al.   ACS Biomaterials-Science & Engineering

Extra-Large Pore Mesoporous Silica Nanoparticles Enabling Co-Delivery of High Amounts of Protein Antigen and Toll-like Receptor 9 Agonist for Enhanced Cancer Vaccine Efficacy

(2018) Bong Geun Cha et al.   ACS Central Science

Peptide Amphiphile Micelle Vaccine Size and Charge Influence the Host Antibody Response

(2018) Rui Zhang et al.   ACS Biomaterials Science & Engineering

Recent advances in applying nanotechnologies for cancer immunotherapy

(2018) Reza Mahjub et al.   JOURNAL OF CONTROLLED RELEASE

Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation

(2018) Inès Mottas et al.   BIOMATERIALS

Cloaking nanoparticles with protein corona shield for targeted drug delivery

(2018) Jun Yong Oh et al.   Nature Communications

Trial Watch: Toll-like receptor agonists in cancer immunotherapy

(2018) Melody Smith et al.   OncoImmunology

Effect of TLR ligands co-encapsulated with multiepitopic antigen in nanoliposomes targeted to human DCs via Fc receptor for cancer vaccines

(2017) Felix Rueda et al.   IMMUNOBIOLOGY

Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights

(2017) María Vallet-Regí et al.   MOLECULES

Dual delivery of siRNA and plasmid DNA using mesoporous silica nanoparticles to differentiate induced pluripotent stem cells into dopaminergic neurons

(2017) Jen-Hsuan Chang et al.   Journal of Materials Chemistry B

Liposomal Formulations in Clinical Use: An Updated Review

(2017) Upendra Bulbake et al.   Pharmaceutics

Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors

(2017) Yingjie Nie et al.   Scientific Reports

Where Are the Nanodrugs? An Industry Perspective on Development of Drug Products Containing Nanomaterials

(2016) Henry A. Havel   AAPS Journal

Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release

(2016) Stefan Datz et al.   Nanoscale

Applicability of avidin protein coated mesoporous silica nanoparticles as drug carriers in the lung

(2016) S. H. van Rijt et al.   Nanoscale

Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery

(2016) Simon Heidegger et al.   Nanoscale

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Imaging of the cross-presenting dendritic cell subsets in the skin-draining lymph node

(2016) Masahiro Kitano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses

(2016) Christian Hotz et al.   OncoImmunology

CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses

(2015) Rodney A. Rosalia et al.   BIOMATERIALS

Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma

(2015) A. H. Rook et al.   BLOOD

Gold Nanoparticles: Recent Advances in the Biomedical Applications

(2015) Xiaoying Zhang   CELL BIOCHEMISTRY AND BIOPHYSICS

Synthetic Nanoparticles for Vaccines and Immunotherapy

(2015) Darrell J. Irvine et al.   CHEMICAL REVIEWS

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells

(2015) Julie Helft et al.   IMMUNITY

Polymeric nanoparticles for co-delivery of synthetic long peptide antigen and poly IC as therapeutic cancer vaccine formulation

(2015) Sima Rahimian et al.   JOURNAL OF CONTROLLED RELEASE

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication

(2015) O. A. Ali et al.   Cancer Immunology Research

PLGA-Based Nanoparticles as Cancer Drug Delivery Systems

(2014) Fatemeh Sadat Tabatabaei Mirakabad et al.   Asian Pacific Journal of Cancer Prevention

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release

(2014) Petr O. Ilyinskii et al.   VACCINE

Tracking and quantification of dendritic cell migration and antigen trafficking between the skin and lymph nodes

(2014) Michio Tomura et al.   Scientific Reports

Mesoporous Silica Nanoparticle Nanocarriers: Biofunctionality and Biocompatibility

(2013) Derrick Tarn et al.   ACCOUNTS OF CHEMICAL RESEARCH

pH-Responsive Nanoparticle Vaccines for Dual-Delivery of Antigens and Immunostimulatory Oligonucleotides

(2013) John T. Wilson et al.   ACS Nano

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response

(2013) Susan N. Thomas et al.   BIOMATERIALS

Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery

(2013) Christian Argyo et al.   CHEMISTRY OF MATERIALS

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice

(2013) Iraklis C. Kourtis et al.   PLoS One

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Mesoporous silicananoparticles for the design of smart delivery nanodevices

(2012) Montserrat Colilla et al.   Biomaterials Science

Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans

(2010) Fiorella Petronzelli et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

pH-Responsive Nanogated Ensemble Based on Gold-Capped Mesoporous Silica through an Acid-Labile Acetal Linker

(2010) Rui Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Colchicine-Loaded Lipid Bilayer-Coated 50 nm Mesoporous Nanoparticles Efficiently Induce Microtubule Depolymerization upon Cell Uptake

(2010) Valentina Cauda et al.   NANO LETTERS

Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals

(2010) Jie Lu et al.   Small

Biotin-Avidin as a Protease-Responsive Cap System for Controlled Guest Release from Colloidal Mesoporous Silica

(2009) Axel Schlossbauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple Core−Shell Functionalized Colloidal Mesoporous Silica Nanoparticles

(2009) Valentina Cauda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mesoporous Silica Nanoparticle-Based Double Drug Delivery System for Glucose-Responsive Controlled Release of Insulin and Cyclic AMP

(2009) Yannan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Colloidal Suspensions of Functionalized Mesoporous Silica Nanoparticles

(2008) Johannes Kobler et al.   ACS Nano

The biocompatibility of mesoporous silicates

(2008) Sarah P. Hudson et al.   BIOMATERIALS

Selective Functionalization of the Outer and Inner Surfaces in Mesoporous Silica Nanoparticles

(2008) Johann Kecht et al.   CHEMISTRY OF MATERIALS