Site-Specific Chemoenzymatic Conjugation of High-Affinity M6P Glycan Ligands to Antibodies for Targeted Protein Degradation
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Site-Specific Chemoenzymatic Conjugation of High-Affinity M6P Glycan Ligands to Antibodies for Targeted Protein Degradation
Authors
Keywords
-
Journal
ACS Chemical Biology
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2022-03-23
DOI
10.1021/acschembio.1c00751
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
- (2021) Adam D. Cotton et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells
- (2021) Ryan Kolb et al. Nature Communications
- Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins
- (2021) Yaxian Zhou et al. ACS Central Science
- LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
- (2021) Green Ahn et al. Nature Chemical Biology
- The oncology market for antibody–drug conjugates
- (2021) Carolina do Pazo et al. NATURE REVIEWS DRUG DISCOVERY
- One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling
- (2021) Chong Ou et al. BIOCONJUGATE CHEMISTRY
- Bifunctional small molecules that mediate the degradation of extracellular proteins
- (2021) David F. Caianiello et al. Nature Chemical Biology
- General and Robust Chemoenzymatic Method for Glycan-Mediated Site-Specific Labeling and Conjugation of Antibodies: Facile Synthesis of Homogeneous Antibody–Drug Conjugates
- (2021) Xiao Zhang et al. ACS Chemical Biology
- Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
- (2020) Sylwia Jones et al. Scientific Reports
- Recent Progress in PROTACs and Other Chemical Protein Degradation Technologies for the Treatment of Neurodegenerative Disorders
- (2020) Shusuke Tomoshige et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Lysosome-targeting chimaeras for degradation of extracellular proteins
- (2020) Steven M. Banik et al. NATURE
- The PROTAC technology in drug development
- (2019) Yutian Zou et al. CELL BIOCHEMISTRY AND FUNCTION
- Glycoengineering of Antibodies for Modulating Functions
- (2019) Lai-Xi Wang et al. Annual Review of Biochemistry
- Targeted protein degradation: expanding the toolbox
- (2019) Matthieu Schapira et al. NATURE REVIEWS DRUG DISCOVERY
- One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes
- (2018) Xin Tong et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6
- (2018) William McCoull et al. ACS Chemical Biology
- Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody
- (2018) John P. Giddens et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Strategies and challenges for the next generation of antibody–drug conjugates
- (2017) Alain Beck et al. NATURE REVIEWS DRUG DISCOVERY
- Modulating IgG effector function by Fc glycan engineering
- (2017) Tiezheng Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemoenzymatic Synthesis of a Phosphorylated Glycoprotein
- (2016) Pragya Priyanka et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling
- (2016) Tiezheng Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins
- (2016) John P. Giddens et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemoenzymatic Synthesis and Receptor Binding of Mannose-6-Phosphate (M6P)-Containing Glycoprotein Ligands Reveal Unusual Structural Requirements for M6P Receptor Recognition
- (2016) Takahiro Yamaguchi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
- (2015) Jing Lu et al. CHEMISTRY & BIOLOGY
- Catalytic in vivo protein knockdown by small-molecule PROTACs
- (2015) Daniel P Bondeson et al. Nature Chemical Biology
- Phthalimide conjugation as a strategy for in vivo target protein degradation
- (2015) G. E. Winter et al. SCIENCE
- Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy
- (2014) Ravi V. J. Chari et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design of a PROTAC that antagonizes and destroys the cancer-forming X-protein of the hepatitis B virus
- (2014) Kristopher Montrose et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- EndoS2is a unique and conserved enzyme of serotype M49 group AStreptococcusthat hydrolyses N-linked glycans on IgG and α1-acid glycoprotein
- (2013) Jonathan Sjögren et al. BIOCHEMICAL JOURNAL
- Endocytosis and autophagy: Shared machinery for degradation
- (2012) Christopher A. Lamb et al. BIOESSAYS
- Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions
- (2012) Wei Huang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Fast analysis of recombinant monoclonal antibodies using IdeS proteolytic digestion and electrospray mass spectrometry
- (2011) Guillaume Chevreux et al. ANALYTICAL BIOCHEMISTRY
- Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
- (2010) J. B. Spangler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient Synthesis of Sugar Oxazolines from UnprotectedN-Acetyl-2-amino Sugars by Using Chloroformamidinium Reagent in Water
- (2009) Masato Noguchi et al. JOURNAL OF ORGANIC CHEMISTRY
- Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose
- (2008) Christine H. Chung et al. NEW ENGLAND JOURNAL OF MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now