Endo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins

A common glycan structure on immunoglobulin G for enhancement of effector functions

(2015) Chin-Wei Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient chemoenzymatic synthesis of an N-glycan isomer library

(2015) Lei Li et al.   Chemical Science

Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities

(2015) Masaki Kurogochi et al.   PLoS One

Chemical and Chemoenzymatic Synthesis of Glycoproteins for Deciphering Functions

(2014) Lai-Xi Wang et al.   CHEMISTRY & BIOLOGY

Galectin-3 in angiogenesis and metastasis

(2014) T. Funasaka et al.   GLYCOBIOLOGY

Emerging Principles for the Therapeutic Exploitation of Glycosylation

(2014) Martin Dalziel et al.   SCIENCE

Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3

(2013) Helen Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The development of synthetic antitumour vaccines from mucin glycopeptide antigens

(2013) Nikola Gaidzik et al.   CHEMICAL SOCIETY REVIEWS

Chemical assembly of N-glycoproteins: a refined toolbox to address a ubiquitous posttranslational modification

(2013) Carlo Unverzagt et al.   CHEMICAL SOCIETY REVIEWS

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG

(2013) Rebecca J. Rose et al.   mAbs

Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies

(2013) Mohammed N Amin et al.   Nature Chemical Biology

Generation of Biologically Active Multi-Sialylated Recombinant Human EPOFc in Plants

(2013) Alexandra Castilho et al.   PLoS One

Glyco-engineering in plants to produce human-like N-glycan structures

(2012) Alexandra Castilho et al.   Biotechnology Journal

Remarkable Transglycosylation Activity of Glycosynthase Mutants of Endo-D, an Endo-β-N-acetylglucosaminidase fromStreptococcus pneumoniae

(2012) Shu-Quan Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemoenzymatic Synthesis of Hydrophobic Glycoprotein: Synthesis of Saposin C Carrying Complex-Type Carbohydrate

(2012) Hironobu Hojo et al.   JOURNAL OF ORGANIC CHEMISTRY

Solving the Convergence Problem in the Synthesis of Triantennary N-Glycan Relevant to Prostate-Specific Membrane Antigen (PSMA)

(2012) Maciej A. Walczak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions

(2012) Wei Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

A “Tag-and-Modify” Approach to Site-Selective Protein Modification

(2011) Justin M. Chalker et al.   ACCOUNTS OF CHEMICAL RESEARCH

Emerging Technologies for Making Glycan-Defined Glycoproteins

(2011) Lai-Xi Wang et al.   ACS Chemical Biology

Unusual Transglycosylation Activity of Flavobacterium meningosepticum Endoglycosidases Enables Convergent Chemoenzymatic Synthesis of Core Fucosylated Complex N-Glycopeptides

(2011) Wei Huang et al.   CHEMBIOCHEM

Enzymes in the Synthesis of Glycoconjugates

(2011) Ryan M. Schmaltz et al.   CHEMICAL REVIEWS

Triggered Mycobacterium tuberculosis Heparin-Binding Hemagglutinin Adhesin Folding and Dimerization

(2011) J. V. Lomino et al.   JOURNAL OF BACTERIOLOGY

Convergent Synthesis of Homogeneous Glc1Man9GlcNAc2-Protein and Derivatives as Ligands of Molecular Chaperones in Protein Quality Control

(2011) Mohammed N. Amin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient transfer of sialo-oligosaccharide onto proteins by combined use of a glycosynthase-like mutant of Mucor hiemalis endoglycosidase and synthetic sialo-complex-type sugar oxazoline

(2010) Midori Umekawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Toward fully synthetic, homogeneous glycoproteins: Advances in chemical ligation

(2010) Yu Yuan et al.   BIOPOLYMERS

Arthrobacter Endo-β-N-Acetylglucosaminidase Shows Transglycosylation Activity on Complex-Type N-Glycan Oxazolines: One-Pot Conversion of Ribonuclease B to Sialylated Ribonuclease C

(2010) Wei Huang et al.   CHEMBIOCHEM

Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens

(2010) Wei Huang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans

(2009) Sabine André et al.   BIOLOGICAL CHEMISTRY

Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins

(2009) Motoko Takahashi et al.   CARBOHYDRATE RESEARCH

Efficient Glycosynthase Mutant Derived fromMucor hiemalisEndo-β-N-acetylglucosaminidase Capable of Transferring Oligosaccharide from Both Sugar Oxazoline and NaturalN-Glycan

(2009) Midori Umekawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient Synthesis of Sugar Oxazolines from UnprotectedN-Acetyl-2-amino Sugars by Using Chloroformamidinium Reagent in Water

(2009) Masato Noguchi et al.   JOURNAL OF ORGANIC CHEMISTRY

Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis ofN-Glycoproteins Carrying Intact NaturalN-Glycans

(2009) Wei Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of the 2,6-Sialylated Immunoglobulin G Glycopeptide Fragment in Homogeneous Form

(2009) Ping Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Emerging methods for the production of homogeneous human glycoproteins

(2009) Jamie R Rich et al.   Nature Chemical Biology

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

(2009) Pieter P Jacobs et al.   Nature Protocols

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Simplified, Enhanced Protein Purification Using an Inducible, Autoprocessing Enzyme Tag

(2009) Aimee Shen et al.   PLoS One

2D Selective-TOCSY–DQFCOSY and HSQC–TOCSY NMR experiments for assignment of a homogeneous asparagine-linked triantennary complex type undecasaccharide

(2008) Hajime Sato et al.   CARBOHYDRATE RESEARCH

Chemoenzymatic synthesis of glycopeptides and glycoproteins through endoglycosidase-catalyzed transglycosylation

(2008) Lai-Xi Wang   CARBOHYDRATE RESEARCH

Glycoprotein Synthesis: An Update

(2008) David P. Gamblin et al.   CHEMICAL REVIEWS

Pre-Activation-Based One-Pot Synthesis of an α-(2,3)-Sialylated Core-Fucosylated Complex Type Bi-Antennary N-Glycan Dodecasaccharide

(2008) Bin Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS