The Role of Gut–Liver Axis in Gut Microbiome Dysbiosis Associated NAFLD and NAFLD-HCC

NAFLD as a metabolic disease in humans: A literature review

(2021) Bertrand Cariou et al.   DIABETES OBESITY & METABOLISM

Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma

(2021) Jason Behary et al.   Nature Communications

Microbiota‐Driven Activation of Intrahepatic B Cells Aggravates Nonalcoholic Steatohepatitis through Innate and Adaptive Signaling

(2021) Fanta Barrow et al.   HEPATOLOGY

The role of farnesoid X receptor in metabolic diseases, and gastrointestinal and liver cancer

(2021) Lulu Sun et al.   Nature Reviews Gastroenterology & Hepatology

Dietary fibers as beneficial microbiota modulators: a proposal classification by prebiotic categories

(2021) Esther Santana Vaz Rezende et al.   NUTRITION

Microbial Metabolites in Colorectal Cancer: Basic and Clinical Implications

(2021) Yao Peng et al.   Metabolites

Non-alcoholic fatty liver disease

(2021) Elizabeth E Powell et al.   LANCET

Emerging and Established Therapeutic Approaches for Nonalcoholic Fatty Liver Disease

(2021) Emily Brown et al.   CLINICAL THERAPEUTICS

Intestinal dysbiosis in nonalcoholic fatty liver disease (NAFLD): focusing on the gut–liver axis

(2021) Hui Han et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Integrative metabolomic characterisation identifies altered portal vein serum metabolome contributing to human hepatocellular carcinoma

(2021) Jinkai Liu et al.   GUT

Mechanistic and physiological approaches of fecal microbiota transplantation in the management of NAFLD

(2021) Manisha Gupta et al.   INFLAMMATION RESEARCH

NAFLD Vs MAFLD – It is not the name but the disease that decides the outcome in fatty liver

(2021) Arka De et al.   JOURNAL OF HEPATOLOGY

The Effect of Probiotics (MCP® BCMC® Strains) on Hepatic Steatosis, Small Intestinal Mucosal Immune Function, and Intestinal Barrier in Patients with Non-Alcoholic Fatty Liver Disease

(2021) Mohamad Hizami Mohamad Nor et al.   Nutrients

Probiotics Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats via Gut Microbiota/FXR/FGF15 Signaling Pathway

(2021) Minmin Luo et al.   Journal of Immunology Research

Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice

(2021) Ryo Aoki et al.   Microbiome

Prebiotic characteristics of arabinogalactans during in vitro fermentation through multi-omics analysis

(2021) Yonggan Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

Akkermansia muciniphila Prevents Fatty Liver, Decreases Serum Triglycerides, and Maintains Gut Homeostasis

(2020) Sejeong Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease

(2020) Mohammed Eslam et al.   GASTROENTEROLOGY

Diet, Gut Microbiota and Non-Alcoholic Fatty Liver Disease: Three Parts of the Same Axis

(2020) Sergio Quesada-Vázquez et al.   Cells

Lactobacillus plantarum NA136 ameliorates nonalcoholic fatty liver disease by modulating gut microbiota, improving intestinal barrier integrity, and attenuating inflammation

(2020) Zijian Zhao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

(2020) Mohammed Eslam et al.   JOURNAL OF HEPATOLOGY

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

(2020) Steven Zhao et al.   NATURE

Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis

(2020) Anja Baumann et al.   Nutrients

A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis

(2020) Tae Gyu Oh et al.   Cell Metabolism

Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites

(2020) Xiang Zhang et al.   GUT

Gut Microbiota Metabolites in NAFLD Pathogenesis and Therapeutic Implications

(2020) Jiezhong Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SCFAs alleviated steatosis and inflammation in mice with NASH induced by MCD

(2020) Mingjuan Deng et al.   JOURNAL OF ENDOCRINOLOGY

Microbiome-based stratification to guide dietary interventions to improve human health

(2020) Zhuang Liu et al.   NUTRITION RESEARCH

Prevalence trends in non-alcoholic fatty liver disease at the global, regional and national levels, 1990–2017: a population-based observational study

(2020) Xiaojun Ge et al.   BMJ Open

Criteria to Qualify Microorganisms as “Probiotic” in Foods and Dietary Supplements

(2020) Sylvie Binda et al.   Frontiers in Microbiology

Advances in the Involvement of Gut Microbiota in Pathophysiology of NAFLD

(2020) Xiaofan Jiang et al.   Frontiers in Medicine

Intestinal permeability in human nonalcoholic fatty liver disease: A systematic review and meta‐analysis

(2020) Toon J. I. De Munck et al.   LIVER INTERNATIONAL

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease

(2020) S.R. Sharpton et al.   Cell Metabolism

Interactions between gut microbiota and non-alcoholic liver disease: the role of microbiota-derived metabolites

(2019) Yufang Ding et al.   PHARMACOLOGICAL RESEARCH

Gut microbiota: novel therapeutic target for nonalcoholic fatty liver disease

(2019) Ki Tae Suk et al.   Expert Review of Gastroenterology & Hepatology

Randomized, Double-blind, Placebo-controlled Study of a Multispecies Probiotic Mixture in Nonalcoholic Fatty Liver Disease

(2019) Sang Bong Ahn et al.   Scientific Reports

Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development

(2019) Juliette Mouries et al.   JOURNAL OF HEPATOLOGY

Hepatocellular carcinoma in non-alcohol fatty liver disease – changing trends and specific challenges

(2019) Aleksandra Berkan-Kawińska et al.   CURRENT MEDICAL RESEARCH AND OPINION

Increased liver localization of lipopolysaccharides in human and experimental non‐alcoholic fatty liver disease

(2019) Guido Carpino et al.   HEPATOLOGY

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

(2019) Zobair M Younossi et al.   LANCET

Metagenome of Gut Microbiota of Children With Nonalcoholic Fatty Liver Disease

(2019) Yuzhen Zhao et al.   Frontiers in Pediatrics

The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

(2018) Charlotte Bayer Christiansen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial

(2018) Marc R. Bomhof et al.   EUROPEAN JOURNAL OF NUTRITION

Human gut microbiome: hopes, threats and promises

(2018) Patrice D Cani   GUT

Hepatocellular carcinoma is associated with gut microbiota profile and inflammation in nonalcoholic fatty liver disease

(2018) Francesca Romana Ponziani et al.   HEPATOLOGY

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Liraglutide modulates gut microbiota and reduces NAFLD in obese mice

(2018) GV Moreira et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut inflammation exacerbates hepatic injury in the high-fat diet induced NAFLD mouse: Attention to the gut-vascular barrier dysfunction

(2018) Chunwei Cheng et al.   LIFE SCIENCES

Interaction of gut microbiota with dysregulation of bile acids in the pathogenesis of nonalcoholic fatty liver disease and potential therapeutic implications of probiotics

(2018) Jiezhong Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

(2018) Taylor K. Soderborg et al.   Nature Communications

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

(2017) Gloria Alvarez-Sola et al.   GUT

Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

(2017) Aafke W. F. Janssen et al.   JOURNAL OF LIPID RESEARCH

Potential prebiotic properties of cashew apple (Anacardium occidentale L.) agro-industrial byproduct on Lactobacillus species

(2017) Francisca Nayara Dantas Duarte et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

Association between endotoxemia and histological features of nonalcoholic fatty liver disease

(2017) Hiroyuki Kitabatake et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

(2017) Da Zhou et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex

(2017) So Yeon Kim et al.   Nature Communications

Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota

(2017) Da Zhou et al.   Scientific Reports

Microbiota-induced obesity requires farnesoid X receptor

(2016) Ava Parséus et al.   GUT

Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach

(2016) Federica Del Chierico et al.   HEPATOLOGY

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

Epidemiology and natural history of non-alcoholic fatty liver disease

(2016) Yousef Fazel et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease

(2016) Marialena Mouzaki et al.   PLoS One

Systematic Review: Adverse Events of Fecal Microbiota Transplantation

(2016) Sinan Wang et al.   PLoS One

Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

(2015) Anna Janina Engstler et al.   GUT

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

(2014) S. A. Joyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut-liver axis and probiotics: Their role in non-alcoholic fatty liver disease

(2014) Giulia Paolella   WORLD JOURNAL OF GASTROENTEROLOGY

Therapeutic Potential of Fecal Microbiota Transplantation

(2013) Loek P. Smits et al.   GASTROENTEROLOGY

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease

(2012) Phillipp Hartmann et al.   Frontiers in Physiology

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

(2011) Erwin Gäbele et al.   JOURNAL OF HEPATOLOGY

Liver Anatomy

(2010) Sherif R. Z. Abdel-Misih et al.   SURGICAL CLINICS OF NORTH AMERICA

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY