Galectin-1 Cooperates with Yersinia Outer Protein (Yop) P to Thwart Protective Immunity by Repressing Nitric Oxide Production

High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming

(2021) Guangan Hu et al.   Nature Communications

Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities

(2020) Juan M. Pérez Sáez et al.   ANGIOGENESIS

Yersinia pestis exploit early activation of myeloid differentiation primary response 88 (MyD88) for growth in the lungs during pneumonic plague

(2019) Rachel M. Olson et al.   INFECTION AND IMMUNITY

Self-defense of macrophages against oxidative injury: Fighting for their own survival

(2019) László Virág et al.   Redox Biology

Glycosylation-dependent galectin–receptor interactions promoteChlamydia trachomatisinfection

(2018) Agustin L. Lujan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Clostridium difficile Immunoreactive Spore Proteins of the Epidemic Strain R20291

(2018) Marjorie Pizarro-Guajardo et al.   Proteomics Clinical Applications

Dimerization: a structural feature for the protection of hepatitis E virus capsid protein against trypsinization

(2018) Wenjuan Wei et al.   Scientific Reports

Regulation of iNOS on Immune Cells and Its Role in Diseases

(2018) Qingjie Xue et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Galectin-1–Driven Tolerogenic Programs AggravateYersinia enterocoliticaInfection by Repressing Antibacterial Immunity

(2017) Roberto C. Davicino et al.   JOURNAL OF IMMUNOLOGY

Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

(2017) Juan P. Cerliani et al.   TRENDS IN BIOCHEMICAL SCIENCES

Immunomodulatory Yersinia outer proteins (Yops)–useful tools for bacteria and humans alike

(2017) Benjamin Grabowski et al.   Virulence

Glycan–protein interactions in viral pathogenesis

(2016) Rahul Raman et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

YopJ Family Effectors Promote Bacterial Infection through a Unique Acetyltransferase Activity

(2016) Ka-Wai Ma et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The role of galectin-4 in physiology and diseases

(2016) Zhan-Qi Cao et al.   Protein & Cell

Superoxide induces protein oxidation in plasma and TNF-α elevation in macrophage culture: Insights into mechanisms of neurotoxicity following doxorubicin chemotherapy

(2015) Jeriel T.R. Keeney et al.   CANCER LETTERS

Trypanosoma cruziInfection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1–Dependent Mechanisms

(2015) Carolina V. Poncini et al.   JOURNAL OF IMMUNOLOGY

Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding

(2015) Mihai Nita-Lazar et al.   MOLECULAR IMMUNOLOGY

Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

(2014) Diego O. Croci et al.   CELL

Galectins as bacterial sensors in the host innate response

(2014) Huan-Yuan Chen et al.   CURRENT OPINION IN MICROBIOLOGY

Microbe–Host Interactions are Positively and Negatively Regulated by Galectin–Glycan Interactions

(2014) Linda G. Baum et al.   Frontiers in Immunology

Identification of secreted bacterial proteins by noncanonical amino acid tagging

(2013) A. Mahdavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease

(2012) T. Dalotto-Moreno et al.   CANCER RESEARCH

Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration

(2012) Sarah C. Starossom et al.   IMMUNITY

Galectin-1 Triggers an Immunoregulatory Signature in Th Cells Functionally Defined by IL-10 Expression

(2012) F. Cedeno-Laurent et al.   JOURNAL OF IMMUNOLOGY

Cell death programs in Yersinia immunity and pathogenesis

(2012) Naomi H. Philip et al.   Frontiers in Cellular and Infection Microbiology

TNFRp55 modulates IL-6 and nitric oxide responses following Yersinia lipopolysaccharide stimulation in peritoneal macrophages

(2011) Ricardo J. Eliçabe et al.   IMMUNOBIOLOGY

Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms

(2011) Roberto C. Davicino et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CytoplasmicN-Glycosyltransferase ofActinobacillus pleuropneumoniaeIs an Inverting Enzyme and Recognizes the NX(S/T) Consensus Sequence

(2011) Flavio Schwarz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1

(2011) Marta A. Toscano et al.   MOLECULAR IMMUNOLOGY

A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages

(2011) Ying Zheng et al.   PLoS Pathogens

Galectins: regulators of acute and chronic inflammation

(2010) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

The Acetyltransferase Activity of the Bacterial Toxin YopJ ofYersiniaIs Activated by Eukaryotic Host Cell Inositol Hexakisphosphate

(2010) Rohit Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lack of TNFR p55 Results in Heightened Expression of IFN-  and IL-17 during the Development of Reactive Arthritis

(2010) R. J. Elicabe et al.   JOURNAL OF IMMUNOLOGY

Nitric oxide controls an inflammatory-like Ly6Chi PDCA1+ DC subset that regulates Th1 immune responses

(2010) Daniela Giordano et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Actinobacillus pleuropneumoniae HMW1C-Like Glycosyltransferase Mediates N-Linked Glycosylation of the Haemophilus influenzae HMW1 Adhesin

(2010) Kyoung-Jae Choi et al.   PLoS One

Innate immune response during Yersinia infection: critical modulation of cell death mechanisms through phagocyte activation

(2009) Tessa Bergsbaken et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10

(2009) Juan M Ilarregui et al.   NATURE IMMUNOLOGY

Roles of galectins in infection

(2009) Gerardo R. Vasta   NATURE REVIEWS MICROBIOLOGY

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Galectin-1 on cervical epithelial cells is a receptor for the sexually transmitted human parasiteTrichomonas vaginalis

(2008) Cheryl Y. M. Okumura et al.   CELLULAR MICROBIOLOGY

Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters

(2008) Liron Belanis et al.   MOLECULAR BIOLOGY OF THE CELL

Susceptibility toYersinia pseudotuberculosisInfection is Linked to the Pattern of Macrophage Activation

(2008) A. Tansini et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY