Regulation of iNOS on Immune Cells and Its Role in Diseases

MicroRNA-34a promotes iNOS secretion from pulmonary macrophages in septic suckling rats through activating STAT3 pathway

(2018) Dong-Liang Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

The protective effects of a novel synthetic β-elemene derivative on human umbilical vein endothelial cells against oxidative stress-induced injury: Involvement of antioxidation and PI3k/Akt/eNOS/NO signaling pathways

(2018) Khalil Ali Ahmad et al.   BIOMEDICINE & PHARMACOTHERAPY

Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity

(2017) Jutamas Suwanpradid et al.   JOURNAL OF IMMUNOLOGY

Targeting iNOS to increase efficacy of immunotherapies

(2017) Suhendan Ekmekcioglu et al.   Human Vaccines & Immunotherapeutics

Myeloid-Derived Suppressor Cells Express Bruton's Tyrosine Kinase and Can Be Depleted in Tumor-Bearing Hosts by Ibrutinib Treatment

(2016) Andrew Stiff et al.   CANCER RESEARCH

Nitric oxide synthase-dependent immune response against gram negative bacteria in a crustacean, Litopenaeus vannamei

(2016) Tania Rodríguez-Ramos et al.   FISH & SHELLFISH IMMUNOLOGY

Dendritic cell-derived nitric oxide inhibits the differentiation of effector dendritic cells

(2016) Chuanping Si et al.   Oncotarget

Human upper airway epithelium produces nitric oxide in response toStaphylococcus epidermidis

(2016) Ryan M. Carey et al.   International Forum of Allergy & Rhinology

Nitric oxide synthase 2 is involved in the pro-tumorigenic potential of γδ17 T cells in melanoma

(2016) Laetitia Douguet et al.   OncoImmunology

The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription

(2015) Priscilla S. Simon et al.   BMC CANCER

H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance

(2015) Amy V. Paschall et al.   JOURNAL OF IMMUNOLOGY

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

(2015) Geming Lu et al.   Nature Communications

iNOS Expression in CD4+ T Cells Limits Treg Induction by Repressing TGF 1: Combined iNOS Inhibition and Treg Depletion Unmask Endogenous Antitumor Immunity

(2014) P. Jayaraman et al.   CLINICAL CANCER RESEARCH

The Role of Myeloid Cell Activation and Arginine Metabolism in the Pathogenesis of Virus-Induced Diseases

(2014) Kristina S. Burrack et al.   Frontiers in Immunology

Regulation of Pathogenic Th17 Cell Differentiation by IL-10 in the Development of Glomerulonephritis

(2013) Ruihua Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2013) Kairui Mao et al.   CELL RESEARCH

Molecular Pathways: Inflammation-Associated Nitric-Oxide Production as a Cancer-Supporting Redox Mechanism and a Potential Therapeutic Target

(2013) E. A. Grimm et al.   CLINICAL CANCER RESEARCH

M1 and M2 Macrophages: Oracles of Health and Disease

(2013) Charles Mills   CRITICAL REVIEWS IN IMMUNOLOGY

T cell–derived inducible nitric oxide synthase switches off TH17 cell differentiation

(2013) Jianjun Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling

(2013) Nataša Obermajer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8 T Cells Regulate Allergic Contact Dermatitis by Modulating CCR2–Dependent TNF/iNOS–Expressing Ly6C + CD11b + Monocytic Cells

(2013) Shu Zhen Chong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Extrinsic and intrinsic control of macrophage inflammatory responses

(2013) Heather B. Cohen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RETRACTED: Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization

(2012) Shaun Spence et al.   IMMUNITY

Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome

(2012) E. Hernandez-Cuellar et al.   JOURNAL OF IMMUNOLOGY

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β

(2012) Bibhuti B Mishra et al.   NATURE IMMUNOLOGY

Murine Myeloid Dendritic Cells That Phagocytose Apoptotic T Cells Inhibit the Immune Response via NO

(2012) Kaili Zhong et al.   PLoS One

Macrophage-Targeted Therapy: CD64-Based Immunotoxins for Treatment of Chronic Inflammatory Diseases

(2012) Dmitrij Hristodorov et al.   Toxins

Regulatory dendritic cells: there is more than just immune activation

(2012) Susanne V. Schmidt et al.   Frontiers in Immunology

Human CD8+ T cells drive Th1 responses through the differentiation of TNF/iNOS-producing dendritic cells

(2011) Shu Zhen Chong et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nitric Oxide Modulates TGF- -Directive Signals To Suppress Foxp3+ Regulatory T Cell Differentiation and Potentiate Th1 Development

(2011) S.-W. Lee et al.   JOURNAL OF IMMUNOLOGY

Myeloid-derived suppressor cells help protective immunity to Leishmania major infection despite suppressed T cell responses

(2011) Wânia F. Pereira et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Production of IFN-β during Listeria monocytogenes Infection Is Restricted to Monocyte/Macrophage Lineage

(2011) Evgenia Solodova et al.   PLoS One

Regulation of type 17 helper T-cell function by nitric oxide during inflammation

(2011) W. Niedbala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the role of Th17 cells in human disease

(2011) Cailin Moira Wilke et al.   TRENDS IN IMMUNOLOGY

Nitric oxide controls an inflammatory-like Ly6Chi PDCA1+ DC subset that regulates Th1 immune responses

(2010) Daniela Giordano et al.   JOURNAL OF LEUKOCYTE BIOLOGY

S-nitrosoglutathione a Physiologic Nitric Oxide Carrier Attenuates Experimental Autoimmune Encephalomyelitis

(2010) Narender Nath et al.   Journal of Neuroimmune Pharmacology

Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

(2010) Tom Bosschaerts et al.   PLoS Pathogens

Are neutrophils important host cells for Leishmania parasites?

(2009) Uwe Ritter et al.   TRENDS IN PARASITOLOGY

Myeloid-Derived Suppressor Cells Promote Cross-Tolerance in B-Cell Lymphoma by Expanding Regulatory T Cells

(2008) P. Serafini et al.   CANCER RESEARCH