A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages

Purifying natively folded proteins from inclusion bodies using sarkosyl, Triton X-100, and CHAPS

(2010) Hu Tao et al.   BIOTECHNIQUES

A Yersinia Effector Protein Promotes Virulence by Preventing Inflammasome Recognition of the Type III Secretion System

(2010) Igor E. Brodsky et al.   Cell Host & Microbe

The Acetyltransferase Activity of the Bacterial Toxin YopJ ofYersiniaIs Activated by Eukaryotic Host Cell Inositol Hexakisphosphate

(2010) Rohit Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitor of NF- B Kinases   and   Are Both Essential for High Mobility Group Box 1-Mediated Chemotaxis

(2010) M. Penzo et al.   JOURNAL OF IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System

(2009) Russell E. Vance et al.   Cell Host & Microbe

Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila

(2009) C. L. Case et al.   INFECTION AND IMMUNITY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Type III Secretion Decreases Bacterial and Host Survival following Phagocytosis of Yersinia pseudotuberculosis by Macrophages

(2008) Y. Zhang et al.   INFECTION AND IMMUNITY

Caspase-1 Activation in Macrophages Infected with Yersinia pestis KIM Requires the Type III Secretion System Effector YopJ

(2008) S. Lilo et al.   INFECTION AND IMMUNITY

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Structural Requirements for Yersinia YopJ Inhibition of MAP Kinase Pathways

(2008) Yi-Heng Hao et al.   PLoS One

Reduced Secretion of YopJ by Yersinia Limits In Vivo Cell Death but Enhances Bacterial Virulence

(2008) Igor E. Brodsky et al.   PLoS Pathogens