Galectin-1–Driven Tolerogenic Programs AggravateYersinia enterocoliticaInfection by Repressing Antibacterial Immunity

Translating the ‘Sugar Code’ into Immune and Vascular Signaling Programs

(2017) Juan P. Cerliani et al.   TRENDS IN BIOCHEMICAL SCIENCES

Galectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-κB–Regulated Gene Network

(2016) Stefan Toegel et al.   JOURNAL OF IMMUNOLOGY

Sugar and Spice Make Bacteria Not Nice: Protein Glycosylation and Its Influence in Pathogenesis

(2016) Ezequiel Valguarnera et al.   JOURNAL OF MOLECULAR BIOLOGY

Epithelial glycosylation in gut homeostasis and inflammation

(2016) Yoshiyuki Goto et al.   NATURE IMMUNOLOGY

Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1

(2016) Xiao Na Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells

(2016) Amelia J. Tesone et al.   Cell Reports

Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation

(2015) Melanie R. Rutkowski et al.   CANCER CELL

Trypanosoma cruziInfection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1–Dependent Mechanisms

(2015) Carolina V. Poncini et al.   JOURNAL OF IMMUNOLOGY

Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding

(2015) Mihai Nita-Lazar et al.   MOLECULAR IMMUNOLOGY

Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells

(2015) Alejandro F. Benatar et al.   PLoS Neglected Tropical Diseases

Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

(2014) Diego O. Croci et al.   CELL

Galectins as bacterial sensors in the host innate response

(2014) Huan-Yuan Chen et al.   CURRENT OPINION IN MICROBIOLOGY

Differential Roles of Galectin-1 and Galectin-3 in Regulating Leukocyte Viability and Cytokine Secretion

(2014) S. R. Stowell et al.   JOURNAL OF IMMUNOLOGY

Targeting galectin-1-induced angiogenesis mitigates the severity of endometriosis

(2014) Juan I Bastón et al.   JOURNAL OF PATHOLOGY

The Leukocyte Activation Receptor CD69 Controls T Cell Differentiation through Its Interaction with Galectin-1

(2014) H. de la Fuente et al.   MOLECULAR AND CELLULAR BIOLOGY

The Role of Galectin-1 and Galectin-3 in the Mucosal Immune Response to Citrobacter rodentium Infection

(2014) Renata Curciarello et al.   PLoS One

Galectin-1 Exerts Inhibitory Effects during DENV-1 Infection

(2014) Karina Alves Toledo et al.   PLoS One

Microbe–Host Interactions are Positively and Negatively Regulated by Galectin–Glycan Interactions

(2014) Linda G. Baum et al.   Frontiers in Immunology

Galectin-1-Mediated Suppression of Pseudomonas aeruginosa-Induced Corneal Immunopathology

(2013) A. Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease

(2012) T. Dalotto-Moreno et al.   CANCER RESEARCH

Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss

(2012) R. E. Ramhorst et al.   GLYCOBIOLOGY

Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration

(2012) Sarah C. Starossom et al.   IMMUNITY

TNFRp55 controls regulatory T cell responses in Yersinia -induced reactive arthritis

(2012) Ethelina Cargnelutti et al.   IMMUNOLOGY AND CELL BIOLOGY

A specific role for TLR1 in protective TH17 immunity during mucosal infection

(2012) R. William DePaolo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma

(2012) Diego O. Croci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Galectin-1 Triggers an Immunoregulatory Signature in Th Cells Functionally Defined by IL-10 Expression

(2012) F. Cedeno-Laurent et al.   JOURNAL OF IMMUNOLOGY

Depletion of Dendritic Cells Enhances Innate Anti-Bacterial Host Defense through Modulation of Phagocyte Homeostasis

(2012) Stella E. Autenrieth et al.   PLoS Pathogens

Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders

(2011) J. Ouyang et al.   BLOOD

Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis

(2011) A. Banh et al.   CANCER RESEARCH

TNFRp55 modulates IL-6 and nitric oxide responses following Yersinia lipopolysaccharide stimulation in peritoneal macrophages

(2011) Ricardo J. Eliçabe et al.   IMMUNOBIOLOGY

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1

(2011) Marta A. Toscano et al.   MOLECULAR IMMUNOLOGY

The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine

(2011) C Muglia et al.   Cell Death & Disease

Yersinia enterocolitica Promotes Robust Mucosal Inflammatory T-Cell Immunity in Murine Neonates

(2010) A. Echeverry et al.   INFECTION AND IMMUNITY

Lack of TNFR p55 Results in Heightened Expression of IFN-  and IL-17 during the Development of Reactive Arthritis

(2010) R. J. Elicabe et al.   JOURNAL OF IMMUNOLOGY

Protein glycosylation in bacteria: sweeter than ever

(2010) Harald Nothaft et al.   NATURE REVIEWS MICROBIOLOGY

Endothelial Galectin-1 Binds to Specific Glycans on Nipah Virus Fusion Protein and Inhibits Maturation, Mobility, and Function to Block Syncytia Formation

(2010) Omai B. Garner et al.   PLoS Pathogens

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10

(2009) Juan M Ilarregui et al.   NATURE IMMUNOLOGY

Roles of galectins in infection

(2009) Gerardo R. Vasta   NATURE REVIEWS MICROBIOLOGY

Yersinia enterocolitica Targets Cells of the Innate and Adaptive Immune System by Injection of Yops in a Mouse Infection Model

(2009) Martin Köberle et al.   PLoS Pathogens

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Role of IFN-gamma and IL-6 in a protective immune response to Yersinia enterocolitica in mice

(2008) Gianluca Matteoli et al.   BMC MICROBIOLOGY

Galectin-1 on cervical epithelial cells is a receptor for the sexually transmitted human parasiteTrichomonas vaginalis

(2008) Cheryl Y. M. Okumura et al.   CELLULAR MICROBIOLOGY

Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function

(2008) Claudia C. Motran et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Crosstalk of signalling processes of innate immunity with Yersinia Yop effector functions

(2008) Klaus Ruckdeschel et al.   IMMUNOBIOLOGY