Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe‐host‐communication in vivo

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

The Uptake, Trafficking, and Biodistribution of Bacteroides thetaiotaomicron Generated Outer Membrane Vesicles

(2020) Emily J. Jones et al.   Frontiers in Microbiology

From Association to Causality: the Role of the Gut Microbiota and Its Functional Products on Host Metabolism

(2020) Ara Koh et al.   MOLECULAR CELL

Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo

(2020) Ivan-Maximiliano Kur et al.   PLOS BIOLOGY

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease

(2020) Jan Wehkamp et al.   Frontiers in Immunology

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

(2020) Min Li et al.   JOURNAL OF CONTROLLED RELEASE

Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo

(2020) Laura Bouchareychas et al.   Cell Reports

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

(2020) Lydia Durant et al.   Microbiome

Characterizing Extracellular Vesicles and Their Diverse RNA Contents

(2020) Eren M. Veziroglu et al.   Frontiers in Genetics

A novel model of injured liver ductal organoids to investigate cholangiocyte apoptosis with relevance to biliary atresia

(2020) Sinobol Chusilp et al.   PEDIATRIC SURGERY INTERNATIONAL

Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis

(2019) Qianquan Ma et al.   Journal of Neuroinflammation

Cushioned-Density Gradient Ultracentrifugation (C-DGUC) improves the isolation efficiency of extracellular vesicles

(2019) Phat Duong et al.   PLoS One

The Healthy Human Blood Microbiome: Fact or Fiction?

(2019) Diego J. Castillo et al.   Frontiers in Cellular and Infection Microbiology

Answers to naysayers regarding microbial extracellular vesicles

(2019) Carolina Coelho et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Extracellular RNAs in periodontopathogenic outer membrane vesicles promote TNF-α production in human macrophages and cross the blood–brain barrier in mice

(2019) Eun-Chong Han et al.   FASEB JOURNAL

The gut-liver axis in liver disease: pathophysiological basis for therapy

(2019) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Outer Membrane Vesiculation Facilitates Surface Exchange and In Vivo Adaptation of Vibrio cholerae

(2019) Franz G. Zingl et al.   Cell Host & Microbe

Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders

(2018) Marialetizia Rastelli et al.   Obesity

Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?

(2018) James A. Tsatsaronis et al.   TRENDS IN MICROBIOLOGY

Fantastic voyage: the journey of intestinal microbiota-derived microvesicles through the body

(2018) Régis Stentz et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer

(2018) Maureen Spit et al.   Open Biology

Large Differences in Small RNA Composition Between Human Biofluids

(2018) Paula M. Godoy et al.   Cell Reports

Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range

(2017) Malte Sielaff et al.   JOURNAL OF PROTEOME RESEARCH

Multiplex, quantitative cellular analysis in large tissue volumes with clearing-enhanced 3D microscopy (Ce3D)

(2017) Weizhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Total Extracellular Small RNA Profiles from Plasma, Saliva and Urine of Healthy Subjects

(2017) Ashish Yeri et al.   Scientific Reports

Lipopolysaccharide structure impacts the entry kinetics of bacterial outer membrane vesicles into host cells

(2017) Eloise J. O’Donoghue et al.   PLoS Pathogens

Intrinsic Defense Mechanisms of the Intestinal Epithelium

(2016) Deepshika Ramanan et al.   Cell Host & Microbe

Mechanisms of outer membrane vesicle entry into host cells

(2016) Eloise J. O'Donoghue et al.   CELLULAR MICROBIOLOGY

Critical Role of LTB4/BLT1 in IL-23–Induced Synovial Inflammation and Osteoclastogenesis via NF-κB

(2016) Laura Bouchareychas et al.   JOURNAL OF IMMUNOLOGY

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

(2016) Laura Broutier et al.   Nature Protocols

Proteomic profiling of Gram-negative bacterial outer membrane vesicles: Current perspectives

(2016) Jaewook Lee et al.   Proteomics Clinical Applications

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

Comprehensive description of blood microbiome from healthy donors assessed by 16S targeted metagenomic sequencing

(2016) Sandrine Païssé et al.   TRANSFUSION

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles

(2016) Katja Koeppen et al.   PLoS Pathogens

Uropathogenic Escherichia coli Releases Extracellular Vesicles That Are Associated with RNA

(2016) Cherie Blenkiron et al.   PLoS One

Efficient Intracellular Delivery of Native Proteins

(2015) Diego S. D’Astolfo et al.   CELL

Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles

(2015) Christina A. Hickey et al.   Cell Host & Microbe

Methods of isolation and purification of outer membrane vesicles from gram-negative bacteria

(2015) Jana Klimentová et al.   MICROBIOLOGICAL RESEARCH

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Gut microbe-derived extracellular vesicles induce insulin resistance, thereby impairing glucose metabolism in skeletal muscle

(2015) Youngwoo Choi et al.   Scientific Reports

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

(2015) Kirsten Ridder et al.   OncoImmunology

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling

(2014) Aaron T. Irving et al.   Cell Host & Microbe

The Intestinal Metabolome: An Intersection Between Microbiota and Host

(2014) Luke K. Ursell et al.   GASTROENTEROLOGY

Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways

(2014) Claudia Günther et al.   GUT

Ultrasensitive proteome analysis using paramagnetic bead technology

(2014) C. S. Hughes et al.   Molecular Systems Biology

In vivo Kinetic Biodistribution of Nano-Sized Outer Membrane Vesicles Derived from Bacteria

(2014) Su Chul Jang et al.   Small

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

Robust Cre-Mediated Recombination in Small Intestinal Stem Cells Utilizing the Olfm4 Locus

(2014) Jurian Schuijers et al.   Stem Cell Reports

Microbial Translocation Across the GI Tract

(2012) Jason M. Brenchley et al.   Annual Review of Immunology

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

(2012) Yue Shen et al.   Cell Host & Microbe

Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life

(2012) Brooke L. Deatherage et al.   INFECTION AND IMMUNITY

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell

(2012) Shiro Yui et al.   NATURE MEDICINE

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

(2011) Claudia Günther et al.   NATURE

Generating intestinal tissue from stem cells: potential for research and therapy

(2011) Jonathan C Howell et al.   Regenerative Medicine

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Virulence and Immunomodulatory Roles of Bacterial Outer Membrane Vesicles

(2010) T. N. Ellis et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

B Cell Activation by Outer Membrane Vesicles—A Novel Virulence Mechanism

(2010) Maria Laura A. Perez Vidakovics et al.   PLoS Pathogens

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology