Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders

Integrative Personal Omics Profiles during Periods of Weight Gain and Loss

(2018) Brian D. Piening et al.   Cell Systems

Energy intake is associated with endotoxemia in apparently healthy men

(2018) Jacques Amar et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Novel insight into the role of microbiota in colorectal surgery

(2017) Radu Bachmann et al.   GUT

Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

(2017) Henrik Munch Roager et al.   GUT

Neurotransmitters: The Critical Modulators Regulating Gut-Brain Axis

(2017) Rahul Mittal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Commensal bacteria make GPCR ligands that mimic human signalling molecules

(2017) Louis J. Cohen et al.   NATURE

Gut microbiota — at the intersection of everything?

(2017) Patrice D. Cani   Nature Reviews Gastroenterology & Hepatology

Health Effects of Overweight and Obesity in 195 Countries over 25 Years

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Diet-driven microbiota dysbiosis is associated with vagal remodeling and obesity

(2017) Tanusree Sen et al.   PHYSIOLOGY & BEHAVIOR

Unconjugated bile acids in rat brain: Analytical method based on LC/ESI-MS/MS with chemical derivatization and estimation of their origin by comparison to serum levels

(2017) Tatsuya Higashi et al.   STEROIDS

Bile Acid Signaling Pathways from the Enterohepatic Circulation to the Central Nervous System

(2017) Kim L. Mertens et al.   Frontiers in Neuroscience

Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

(2017) Lucy Brooks et al.   Molecular Metabolism

Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome

(2017) Tess Pallister et al.   Scientific Reports

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth

(2016) Jonathan Breton et al.   Cell Metabolism

Colonic acetate in obesity: location matters!

(2016) L. B. Bindels et al.   CLINICAL SCIENCE

Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system

(2016) Niall P. Hyland et al.   DEVELOPMENTAL BIOLOGY

Formation of propionate and butyrate by the human colonic microbiota

(2016) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Gut microbiome and liver diseases

(2016) Herbert Tilg et al.   GUT

Gut microbiota, metabolome and immune signatures in patients with uncomplicated diverticular disease

(2016) Giovanni Barbara et al.   GUT

Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

(2016) M S Svane et al.   INTERNATIONAL JOURNAL OF OBESITY

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

The Neuro-endocrinological Role of Microbial Glutamate and GABA Signaling

(2016) Roberto Mazzoli et al.   Frontiers in Microbiology

How gut microbes talk to organs: The role of endocrine and nervous routes

(2016) Patrice D. Cani et al.   Molecular Metabolism

Microbial regulation of GLP-1 and L-cell biology

(2016) Thomas U. Greiner et al.   Molecular Metabolism

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum

(2015) Chloe M. Stenkamp-Strahm et al.   CELL AND TISSUE RESEARCH

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

Jejunal T Cell Inflammation in Human Obesity Correlates with Decreased Enterocyte Insulin Signaling

(2015) Milena Monteiro-Sepulveda et al.   Cell Metabolism

The influence of diet on the gut microbiota and its consequences for health

(2015) Joël Doré et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bile Acids as Hormones: The FXR-FGF15/19 Pathway

(2015) Steven A. Kliewer et al.   DIGESTIVE DISEASES

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

(2015) Christopher S. Reigstad et al.   FASEB JOURNAL

Apelin targets gut contraction to control glucose metabolism via the brain

(2015) Audren Fournel et al.   GUT

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

(2015) Isabelle Magalhaes et al.   JOURNAL OF CLINICAL INVESTIGATION

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Endocannabinoids — at the crossroads between the gut microbiota and host metabolism

(2015) Patrice D. Cani et al.   Nature Reviews Endocrinology

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Improving glucose tolerance via the gut–brain axis

(2015) Christine Weber   Nature Reviews Gastroenterology & Hepatology

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia

(2015) M.K. Nøhr et al.   NEUROSCIENCE

Chronic exposure to Low dose bacterial lipopolysaccharide inhibits leptin signaling in vagal afferent neurons

(2015) Claire B. de La Serre et al.   PHYSIOLOGY & BEHAVIOR

Expression of tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery

(2015) Anna Casselbrant et al.   Surgery for Obesity and Related Diseases

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota

(2015) Lucie Geurts et al.   Nature Communications

Fat deposition in the tunica muscularis and decrease of interstitial cells of Cajal and nNOS-positive neuronal cells in the aged rat colon

(2014) Hyun Jin Jo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

Circulating zonulin levels in newly diagnosed Chinese type 2 diabetes patients

(2014) D. Zhang et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Enteric Glial Cells: Recent Developments and Future Directions

(2014) Michel Neunlist et al.   GASTROENTEROLOGY

Alterations of the human gut microbiome in liver cirrhosis

(2014) Nan Qin et al.   NATURE

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

(2014) Michèle Crumeyrolle-Arias et al.   PSYCHONEUROENDOCRINOLOGY

Gut microbiota and GLP-1

(2014) Amandine Everard et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

(2014) Amandine Everard et al.   Nature Communications

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders

(2014) N Tennoune et al.   Translational Psychiatry

High-fat diet and age-dependent effects on enteric glial cell populations of mouse small intestine

(2013) Chloe Stenkamp-Strahm et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials

(2013) Nicole J. Kellow et al.   BRITISH JOURNAL OF NUTRITION

Properties of myenteric neurones and mucosal functions in the distal colon of diet-induced obese mice

(2013) François Reichardt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes

(2013) B. Jayashree et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism

(2013) Geneviève Marcelin et al.   Molecular Metabolism

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

(2012) Yasunari Asano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Voices from within: gut microbes and the CNS

(2012) Paul Forsythe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice

(2012) B. M. Carvalho et al.   DIABETOLOGIA

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

(2012) Evelyne M Dewulf et al.   GUT

γ-Aminobutyric acid production by culturable bacteria from the human intestine

(2012) E. Barrett et al.   JOURNAL OF APPLIED MICROBIOLOGY

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Endotoxemia Is Associated With an Increased Risk of Incident Diabetes

(2011) P. J. Pussinen et al.   DIABETES CARE

Bifidobacterium longum with Fructo-Oligosaccharides in Patients with Non Alcoholic Steatohepatitis

(2011) Michele Malaguarnera et al.   DIGESTIVE DISEASES AND SCIENCES

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

(2011) Premysl Bercik et al.   GASTROENTEROLOGY

Gut feelings: the emerging biology of gut–brain communication

(2011) Emeran A. Mayer   NATURE REVIEWS NEUROSCIENCE

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor

(2010) Martha C. Washington et al.   BRAIN RESEARCH

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

(2010) Rodolphe Soret et al.   GASTROENTEROLOGY

Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation

(2010) Fabienne Laugerette et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The endocannabinoid system links gut microbiota to adipogenesis

(2010) Giulio G Muccioli et al.   Molecular Systems Biology

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Peripheral motor action of glucagon-like peptide-1 through enteric neuronal receptors

(2010) A. Amato et al.   NEUROGASTROENTEROLOGY AND MOTILITY

A Gut Feeling about GABA: Focus on GABAB Receptors

(2010) Niall P. Hyland et al.   Frontiers in Pharmacology

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Bacterial Nitric-oxide Synthases Operate without a Dedicated Redox Partner

(2008) Ivan Gusarov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY