Insights Into the Biological Role of NEDD4L E3 Ubiquitin Ligase in Human Cancers
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Title
Insights Into the Biological Role of NEDD4L E3 Ubiquitin Ligase in Human Cancers
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-11-15
DOI
10.3389/fonc.2021.774648
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Note: Only part of the references are listed.- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3
- (2021) Peng Gao et al. Nature Communications
- Exosomes Derived From Macrophages Enhance Aerobic Glycolysis and Chemoresistance in Lung Cancer by Stabilizing c-Myc via the Inhibition of NEDD4L
- (2021) Huan Wang et al. Frontiers in Cell and Developmental Biology
- Construction of a Nine-MicroRNA-Based Signature to Predict the Overall Survival of Esophageal Cancer Patients
- (2021) Xiaobin Zhang et al. Frontiers in Genetics
- Exploring the Roles of HERC2 and the NEDD4L HECT E3 Ubiquitin Ligase Subfamily in p53 Signaling and the DNA Damage Response
- (2021) Nicholas A. Mathieu et al. Frontiers in Oncology
- Dexamethasone enhances the lung metastasis of breast cancer via a PI3K-SGK1-CTGF pathway
- (2021) Yujing Zhang et al. ONCOGENE
- Ubiquitination Destabilizes Protein Sphingosine Kinase 2 to Regulate Glioma Malignancy
- (2021) Hongliang Wang et al. Frontiers in Cellular Neuroscience
- ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L
- (2021) Weijie Zhang et al. Cell Death & Disease
- Integrated bioinformatics analysis of the NEDD4 family reveals a prognostic value of NEDD4L in clear-cell renal cell cancer
- (2021) Hui Zhao et al. PeerJ
- Copper Promotes Tumorigenesis by Activating the PDK1‐AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner
- (2021) Jianping Guo et al. Advanced Science
- Lung Cancer 2020
- (2020) Brett C. Bade et al. CLINICS IN CHEST MEDICINE
- Epidemiology of breast cancer, a paradigm of the “common soil” hypothesis
- (2020) Licia Iacoviello et al. SEMINARS IN CANCER BIOLOGY
- NEDD4L downregulates autophagy and cell growth by modulating ULK1 and a glutamine transporter
- (2020) Dong-Eun Lee et al. Cell Death & Disease
- Prediagnostic serum selenium levels in relation to breast cancer survival and tumor characteristics
- (2020) Malte Sandsveden et al. INTERNATIONAL JOURNAL OF CANCER
- Increased expression of microRNA-93 correlates with progression and prognosis of prostate cancer
- (2020) Chongshan Wang et al. MEDICINE
- NEDD4 E3 ligase: Functions and mechanism in human cancer
- (2020) Zhi-wei Wang et al. SEMINARS IN CANCER BIOLOGY
- M2 macrophage‐derived exosomes facilitate hepatocarcinoma metastasis by transferring α M β 2 integrin to tumor cells
- (2020) Jindao Wu et al. HEPATOLOGY
- Regulators of Epithelial Sodium Channels in Aldosterone-Sensitive Distal Nephrons (ASDN): Critical Roles of Nedd4L/Nedd4-2 and Salt-Sensitive Hypertension
- (2020) Tomoaki Ishigami et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- NEDD4L-mediated LTF protein degradation limits ferroptosis
- (2020) Yuan Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Gastric cancer
- (2020) Elizabeth C Smyth et al. LANCET
- The role of ubiquitination and deubiquitination in cancer metabolism
- (2020) Tianshui Sun et al. Molecular Cancer
- MicroRNA‑23a acts as an oncogene in pancreatic carcinoma by targeting TFPI‑2
- (2020) Wei Wang et al. Experimental and Therapeutic Medicine
- STK35 Is Ubiquitinated by NEDD4L and Promotes Glycolysis and Inhibits Apoptosis Through Regulating the AKT Signaling Pathway, Influencing Chemoresistance of Colorectal Cancer
- (2020) Haojun Yang et al. Frontiers in Cell and Developmental Biology
- Endometrial Cancer
- (2020) Karen H. Lu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Differential epigenetic profiles induced by sodium selenite in breast cancer cells
- (2020) Zhuo-Zhi Liang et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Epithelial ovarian cancer
- (2019) Stephanie Lheureux et al. LANCET
- Decreased expression of NEDD4L contributes to NSCLC progression and metastasis
- (2019) Xuming Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Whole-Exome Sequencing of Nasopharyngeal Carcinoma Families Reveals Novel Variants Potentially Involved in Nasopharyngeal Carcinoma
- (2019) Guoqin Yu et al. Scientific Reports
- Differentially expressed tRFs in CD5 positive relapsed & refractory diffuse large B cell lymphoma and the bioinformatic analysis for their potential clinical use
- (2019) Qingyuan Qu et al. Biology Direct
- Emerging Roles of DDB2 in Cancer
- (2019) Pauline Gilson et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor
- (2019) Laura Novellasdemunt et al. EMBO JOURNAL
- IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway
- (2019) Ku-Chung Chen et al. PLoS One
- TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription
- (2019) Jin-mei Yu et al. Nature Communications
- Downregulation of Nedd4L predicts poor prognosis, promotes tumor growth and inhibits MAPK/ERK signal pathway in hepatocellular carcinoma
- (2018) Fengbo Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection
- (2018) Jessy Hasna et al. CELL DEATH AND DIFFERENTIATION
- Ubiquitination: Friend and foe in cancer
- (2018) Mohammed A. Mansour INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Neural precursor cell-expressed developmentally down-regulated 4-like: a new biomarker in the pathophysiology of endometrial cancer
- (2018) Ercan Yilmaz et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3
- (2018) Jinghui Zhang et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L
- (2018) A. L. Guarnieri et al. ONCOGENE
- Physiological Functions of Nedd4-2: Lessons from Knockout Mouse Models
- (2018) Jantina A. Manning et al. TRENDS IN BIOCHEMICAL SCIENCES
- DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1
- (2018) Tiantian Cui et al. Cell Death & Disease
- Genome-Wide Methylation Patterns in Androgen-Independent Prostate Cancer Cells: A Comprehensive Analysis Combining MeDIP-Bisulfite, RNA, and microRNA Sequencing Data
- (2018) Yumin Wang et al. Genes
- Wogonin Attenuates Isoprenaline-Induced Myocardial Hypertrophy in Mice by Suppressing the PI3K/Akt Pathway
- (2018) Weichun Qian et al. Frontiers in Pharmacology
- MicroRNA-93 promotes bladder cancer proliferation and invasion by targeting PEDF
- (2018) Hua Jiang et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly
- (2017) Dustin R. Todaro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wnt/β-catenin activation and macrophage induction during liver cancer development following steatosis
- (2017) A Debebe et al. ONCOGENE
- Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update
- (2017) Aarti Sharma et al. WORLD JOURNAL OF GASTROENTEROLOGY
- MiR-93 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer Cells by Activating the PI3K/Akt Pathway via Inhibition of LKB1/PTEN/CDKN1A
- (2017) Chunmei Li et al. Journal of Cancer
- Targeting Cellular Signaling Pathways in Breast Cancer Stem Cells and its Implication for Cancer Treatment
- (2016) BRUNO RICARDO BARRETO PIRES et al. ANTICANCER RESEARCH
- Endoplasmic reticulum stress up-regulates Nedd4-2 to induce autophagy
- (2016) Hao Wang et al. FASEB JOURNAL
- NEDD4L Protein Catalyzes Ubiquitination of PIK3CA Protein and Regulates PI3K-AKT Signaling
- (2016) Zixi Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural insights into the catalysis and regulation of E3 ubiquitin ligases
- (2016) Lori Buetow et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- NEDD4-2 (NEDD4L): The ubiquitin ligase for multiple membrane proteins
- (2015) Pranay Goel et al. GENE
- Nedd4L expression is decreased in ovarian epithelial cancer tissues compared to ovarian non-cancer tissue
- (2015) Qiuyun Yang et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
- Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression
- (2015) Adam E Frampton et al. LANCET
- Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms
- (2015) Chen Wei et al. MOLECULAR BIOLOGY OF THE CELL
- DDB2 modulates TGF-β signal transduction in human ovarian cancer cells by downregulating NEDD4L
- (2015) Ran Zhao et al. NUCLEIC ACIDS RESEARCH
- miR-93 promotes TGF-β-induced epithelial-to-mesenchymal transition through downregulation of NEDD4L in lung cancer cells
- (2015) Mei-Hua Qu et al. TUMOR BIOLOGY
- Signaling through C2 domains: More than one lipid target
- (2014) Senena Corbalan-Garcia et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- NEDD4: A Promising Target for Cancer Therapy
- (2014) Xiantao Ye et al. CURRENT CANCER DRUG TARGETS
- The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex
- (2014) Emily B Heikamp et al. NATURE IMMUNOLOGY
- Structural and Functional Framework for the Autoinhibition of Nedd4-Family Ubiquitin Ligases
- (2014) Sara Mari et al. STRUCTURE
- Identification of the NEDD4L Gene as a Prognostic Marker by Integrated Microarray Analysis of Copy Number and Gene Expression Profiling in Non-small Cell Lung Cancer
- (2013) Hiroyuki Sakashita et al. ANNALS OF SURGICAL ONCOLOGY
- MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression
- (2013) Adam E. Frampton et al. GASTROENTEROLOGY
- Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma
- (2013) Yusuke Kito et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- HECT Domain-containing E3 Ubiquitin Ligase NEDD4L Negatively Regulates Wnt Signaling by Targeting Dishevelled for Proteasomal Degradation
- (2013) Yi Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NEDD4L Is Downregulated in Colorectal Cancer and Inhibits Canonical WNT Signaling
- (2013) Jarred P. Tanksley et al. PLoS One
- Linear ubiquitination: a newly discovered regulator of cell signalling
- (2013) Eva Rieser et al. TRENDS IN BIOCHEMICAL SCIENCES
- Early dynamic transcriptomic changes during preoperative radiotherapy in patients with rectal cancer: A feasibility study
- (2013) Stephane Supiot WORLD JOURNAL OF GASTROENTEROLOGY
- The Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling Pathways
- (2012) Zaklina Kovacevic et al. ANTIOXIDANTS & REDOX SIGNALING
- Role of altered expression of Nedd4L in the pathogenesis of systemic malignancies
- (2012) Shailendra Kapoor et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Down-regulation of Nedd4L is Associated with the Aggressive Progression and Worse Prognosis of Malignant Glioma
- (2012) S. He et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Decreased expression of Nedd4L correlates with poor prognosis in gastric cancer patient
- (2011) Chengcheng Gao et al. MEDICAL ONCOLOGY
- The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation
- (2011) Allan M. Weissman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer
- (2010) Tamotsu Takeuchi et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Transcription alterations of members of the ubiquitin–proteasome network in prostate carcinoma
- (2010) O J C Hellwinkel et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions
- (2009) B Yang et al. CELL DEATH AND DIFFERENTIATION
- Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-β Signaling
- (2009) Sheng Gao et al. MOLECULAR CELL
- Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays
- (2009) Avinash Persaud et al. Molecular Systems Biology
- Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic
- (2008) A. B. Sherk et al. CANCER RESEARCH
- Nedd4L expression is downregulated in prostate cancer compared to benign prostatic hyperplasia
- (2008) X.Y. Hu et al. EJSO
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