Glucosinolates and their hydrolysis products as potential nutraceuticals to combat cytokine storm in SARS-COV-2

Antioxidant activity of two edible isothiocyanates: sulforaphane and erucin is due to their thermal decomposition to sulfenic acids and methylsulfinyl radicals

(2021) Jakub Cedrowski et al.   FOOD CHEMISTRY

COVID-19, cytokines, inflammation, and spices: How are they related?

(2021) Ajaikumar B. Kunnumakkara et al.   LIFE SCIENCES

Monocytes and macrophages in COVID-19: Friends and foes

(2021) Sepideh Meidaninikjeh et al.   LIFE SCIENCES

Potential of Sulforaphane as a Natural Immune System Enhancer: A Review

(2021) Andrea Mahn et al.   MOLECULES

Nrf2 a molecular therapeutic target for Astaxanthin

(2021) Zeynab Kohandel et al.   BIOMEDICINE & PHARMACOTHERAPY

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein

(2021) Jessica Gasparello et al.   PHYTOMEDICINE

Flavonoids against the SARS-CoV-2 induced inflammatory storm

(2021) Alena Liskova et al.   BIOMEDICINE & PHARMACOTHERAPY

Network pharmacology study on the mechanism of the Chinese medicine Radix Isatidis (Banlangen) for COVID-19

(2021) Bin Yu et al.   MEDICINE

Glucose-6-phosphate dehydrogenase inhibitor for treatment of severe COVID-19: Polydatin

(2021) Amir Hossein Doustimotlagh et al.   Clinical Nutrition ESPEN

Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1

(2020) Vivek Patel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action

(2020) Li-xing Nie et al.   JOURNAL OF ETHNOPHARMACOLOGY

Three Novel Prevention, Diagnostic and Treatment Options for COVID-19 Urgently Necessitating Controlled Randomized Trials

(2020) Richard I. Horowitz et al.   MEDICAL HYPOTHESES

Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients

(2020) R. A. Zinovkin et al.   BIOCHEMISTRY-MOSCOW

Isolation, identification, biological estimation, and profiling of glucosinolates in Isatis indigotica roots

(2020) Qihui Guo et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Human, Animal and Plant Health Benefits of Glucosinolates and Strategies for Enhanced Bioactivity: A Systematic Review

(2020) Sylvia Maina et al.   MOLECULES

Potential Role of Nrf2 Activators with Dual Antiviral and Anti-Inflammatory Properties in the Management of Viral Pneumonia

(2020) Chih-Yin Lin et al.   Infection and Drug Resistance

Mechanisms Underlying Biological Effects of Cruciferous Glucosinolate-Derived Isothiocyanates/Indoles: A Focus on Metabolic Syndrome

(2020) Montserrat Esteve   Frontiers in Nutrition

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

(2020) Shalki Choudhary et al.   MICROBIAL PATHOGENESIS

Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

(2020) Jean Bousquet et al.   World Allergy Organization Journal

Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease

(2019) Christine A. Houghton   Oxidative Medicine and Cellular Longevity

Effects of long-term consumption of broccoli sprouts on inflammatory markers in overweight subjects

(2018) María Teresa López-Chillón et al.   CLINICAL NUTRITION

Protective Effect of Glucosinolates Hydrolytic Products in Neurodegenerative Diseases (NDDs)

(2018) Mohammed Jaafaru et al.   Nutrients

Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury in mice

(2018) Berrak Caglayan et al.   MOLECULAR BIOLOGY REPORTS

Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers

(2018) Prabhakaran Soundararajan et al.   MOLECULES

Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes

(2018) Hoai T. T. Tran et al.   Frontiers in Immunology

Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sinigrin and Its Therapeutic Benefits

(2016) Anisha Mazumder et al.   MOLECULES

Antiinflammatory activity of glucomoringin isothiocyanate in a mouse model of experimental autoimmune encephalomyelitis

(2014) Maria Galuppo et al.   FITOTERAPIA

Toll-like Receptors as a Target of Food-derived Anti-inflammatory Compounds

(2014) Takahiro Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protective Role of (RS)-glucoraphanin Bioactivated with Myrosinase in an Experimental Model of Multiple Sclerosis

(2013) Sabrina Giacoppo et al.   CNS Neuroscience & Therapeutics

Erucin Exerts Anti-Inflammatory Properties in Murine Macrophages and Mouse Skin: Possible Mediation through the Inhibition of NFκB Signaling

(2013) Han Cho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin

(2013) Insa M.A. Ernst et al.   PHARMACOLOGICAL RESEARCH

Isothiocyanates Ameliorate the Symptom of Heart Dysfunction and Mortality in a Murine AIDS Model by Inhibiting Apoptosis in the Left Ventricle

(2012) Jin-Nyoung Ho et al.   JOURNAL OF MEDICINAL FOOD

Biotransformation of Glucosinolates Epiprogoitrin and Progoitrin to (R)- and (S)-Goitrin inRadix isatidis

(2011) Zhiyong Xie et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention

(2009) Ka Lung Cheung et al.   AAPS Journal

The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo

(2009) Dario Brunelli et al.   BIOCHEMICAL PHARMACOLOGY