Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1

Moringa Isothiocyanate Activates Nrf2: Potential Role in Diabetic Nephropathy

(2019) David Cheng et al.   AAPS Journal

Oxygen radical disease in the newborn, revisited: Oxidative stress and disease in the newborn period

(2019) Marta Perez et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases

(2019) Mao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress induced necroptosis activation is involved in the pathogenesis of hyperoxic acute lung injury

(2018) C.H. Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nrf2-Keap1 signaling in oxidative and reductive stress

(2018) Ilaria Bellezza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Acute Respiratory Distress Syndrome

(2018) Eddy Fan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Canonical and non-canonical mechanisms of Nrf2 activation

(2018) Carlos Alfredo Silva-Islas et al.   PHARMACOLOGICAL RESEARCH

Hyperoxia-induced regulation of cough reflex and its effect after antioxidant supplementation

(2018) Mariana Brozmanova et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Protective mechanism of sulforaphane in Nrf2 and anti-lung injury in ARDS rabbits

(2018) Zongjian Sun et al.   Experimental and Therapeutic Medicine

Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice

(2018) Hye-Youn Cho et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress

(2017) Takafumi Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanical Ventilation: State of the Art

(2017) Tài Pham et al.   MAYO CLINIC PROCEEDINGS

Sulforaphane increases Nrf2 expression and protects alveolar epithelial cells against injury caused by cigarette smoke extract

(2017) Zongxian Jiao et al.   Molecular Medicine Reports

Vitamin C and Immune Function

(2017) Anitra Carr et al.   Nutrients

Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense against Pulmonary Bacterial Infection

(2016) Vivek S. Patel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

3-O-Laurylglyceryl ascorbate activates the intracellular antioxidant system through the contribution of PPAR-γ and Nrf2

(2016) Yushi Katsuyama et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Molecular mechanisms underlying hyperoxia acute lung injury

(2016) Francisca Dias-Freitas et al.   RESPIRATORY MEDICINE

The Compromise of Macrophage Functions by Hyperoxia Is Attenuated by Ethacrynic Acid via Inhibition of NF-κB–Mediated Release of High-Mobility Group Box-1

(2015) Mao Wang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response

(2015) Ryota Saito et al.   MOLECULAR AND CELLULAR BIOLOGY

High Mobility Group Protein-1 Inhibits Phagocytosis of Apoptotic Neutrophils through Binding to Phosphatidylserine

(2014) G. Liu et al.   JOURNAL OF IMMUNOLOGY

Ascorbic Acid: Its Role in Immune System and Chronic Inflammation Diseases

(2014) Angela Sorice et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane

(2014) Danielle L. Folkard et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury

(2014) Maria Entezari et al.   Redox Biology

High Mobility Group Box–1 Mediates Hyperoxia-Induced Impairment ofPseudomonas aeruginosaClearance and Inflammatory Lung Injury in Mice

(2013) Vivek S. Patel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hyperoxic Acute Lung Injury

(2013) R. H. Kallet et al.   Respiratory Care

Ascorbic acid: Chemistry, biology and the treatment of cancer

(2012) Juan Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes

(2012) M. La Marca et al.   FOOD AND CHEMICAL TOXICOLOGY

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(2012) Maria Entezari et al.   MOLECULAR MEDICINE

Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China

(2011) P. A. Egner et al.   Cancer Prevention Research

Intracellular HMGB1 Negatively Regulates Efferocytosis

(2011) S. Banerjee et al.   JOURNAL OF IMMUNOLOGY

HMGB1 inhibits macrophage activity in efferocytosis through binding to the αvβ3-integrin

(2010) Arnaud Friggeri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hyperoxia sensing: From molecular mechanisms to significance in disease

(2010) Ashwini Gore et al.   Journal of Immunotoxicology

The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis

(2010) Sami Banerjee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

PULMONARY LEVELS OF HIGH-MOBILITY GROUP BOX 1 DURING MECHANICAL VENTILATION AND VENTILATOR-ASSOCIATED PNEUMONIA

(2009) Marieke A.D. van Zoelen et al.   SHOCK

Molecular mechanisms of hyperoxia-induced acute lung injury

(2008) Vineet Bhandari   Frontiers in Bioscience-Landmark