ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss

Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer

(2020) Hong-Yi Liu et al.   NUCLEIC ACIDS RESEARCH

Abnormal inhibition of osteoclastogenesis by mesenchymal stem cells through the miR-4284/CXCL5 axis in ankylosing spondylitis

(2019) Wenjie Liu et al.   Cell Death & Disease

Role of Epigenomics in Bone and Cartilage Disease

(2019) Joyce BJ van Meurs et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2

(2019) Jinteng Li et al.   CELL DEATH AND DIFFERENTIATION

Bone remodelling in vitro : Where are we headed?

(2018) Nupur Kohli et al.   BONE

Plastrum Testudinis Extracts Promote BMSC Proliferation and Osteogenic Differentiation by Regulating Let-7f-5p and the TNFR2/PI3K/AKT Signaling Pathway

(2018) Geng-Yang Shen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Preclinical Studies of Stem Cell Therapy for Heart Disease

(2018) Bryon A. Tompkins et al.   CIRCULATION RESEARCH

Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis

(2018) Huan Jing et al.   Cell Death & Disease

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

(2018) Gabriel Balmus et al.   Nature Communications

Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress

(2018) Xiaofeng Liu et al.   NUCLEIC ACIDS RESEARCH

Acetylation of Cytidine in mRNA Promotes Translation Efficiency

(2018) Daniel Arango et al.   CELL

LncRNA-OG Promotes the Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells Under the Regulation of hnRNPK

(2018) Su'an Tang et al.   STEM CELLS

Epigenetic Control of Mesenchymal Stem Cell Fate Decision via Histone Methyltransferase Ash1l

(2018) Bei Yin et al.   STEM CELLS

Declining histone acetyltransferase GCN5 represses BMSC-mediated angiogenesis during osteoporosis

(2017) Huan Jing et al.   FASEB JOURNAL

Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways

(2017) Xiao-li Zhao et al.   Scientific Reports

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

(2016) Q Chen et al.   CELL DEATH AND DIFFERENTIATION

Key transcription factors in the differentiation of mesenchymal stem cells

(2016) Sami G. Almalki et al.   DIFFERENTIATION

NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2

(2016) Xiaofeng Liu et al.   EMBO REPORTS

Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices?

(2016) Francesca Marini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis

(2016) Paul D. Miller et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Romosozumab Treatment in Postmenopausal Women with Osteoporosis

(2016) Felicia Cosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histone Acetyltransferase GCN5 Regulates Osteogenic Differentiation of Mesenchymal Stem Cells by Inhibiting NF-κB

(2015) Ping Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

(2015) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

Associations of polymorphisms in NAT2 gene with risk and metastasis of osteosarcoma in young Chinese population

(2015) Zhengxiang Huang et al.   OncoTargets and Therapy

Human NAT10 Is an ATP-dependent RNA Acetyltransferase Responsible forN4-Acetylcytidine Formation in 18 S Ribosomal RNA (rRNA)

(2014) Satoshi Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells

(2014) D. Larrieu et al.   SCIENCE

Stem Cell Therapy for Osteoporosis

(2014) Ben Antebi et al.   Current Osteoporosis Reports

Conformational Preferences of Modified Nucleoside N(4)-Acetylcytidine, ac4C Occur at “Wobble” 34th Position in the Anticodon Loop of tRNA

(2013) Bajarang V. Kumbhar et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

(2013) Lionel Tafforeau et al.   MOLECULAR CELL

Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts

(2013) Maya Fakhry   World Journal of Stem Cells

Oleanolic acid exerts an osteoprotective effect in ovariectomy-induced osteoporotic rats and stimulates the osteoblastic differentiation of bone mesenchymal stem cells in vitro

(2011) Qin Bian et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Proper Gcn5 histone acetyltransferase expression is required for normal anteroposterior patterning of the mouse skeleton

(2010) Wenchu Lin et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

NAT10, a nucleolar protein, localizes to the midbody and regulates cytokinesis and acetylation of microtubules

(2009) Qi Shen et al.   EXPERIMENTAL CELL RESEARCH

Combination of bone tissue engineering and BMP-2 gene transfection promotes bone healing in osteoporotic rats

(2008) Youchao Tang et al.   CELL BIOLOGY INTERNATIONAL

Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease

(2008) Ann E. Kearns et al.   ENDOCRINE REVIEWS